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Control del Ciclo Estral con ProgesteronaAlberto DickUniversidad Nacional del Centro de la Provincia de Buenos AiresTandilArgentina
Estrategias para Sincronizar y Resincronizar el Celo y la Ovulation en Ganado de LecheAlberto DickDepartamento de Produccin AnimalProduccin Bovinos de Leche y Carne
Facultad de Ciencias VeterinariasTandil, Argentina
Programas de Sincronizacin del CeloFacilita IAReduce tiempo requerido para detectar celoAdelanta la fecha del primer servicio artificialCapaz de ser usado (con mnimas variaciones), en animales cclicos y no cclicosInduce la ciclicidad en vaquillonas prepberes y vacas en anestroEn animales cclicos, logra % similares de concepcin que en vacas no tratadasPerodo de Inseminacin desde 1 a 3 das
Productos Disponibles en la ActualidadProstaglandina F2Lutalyse, Estrumate, y 22 marcas +GnRHCystorelin, FertagylProgestgenosCIDR, DIB, DIA, Cue-Mate, Triu-B (progesterone) y Crestar (Norgestomet)EstrgenosEstradiol (Benzoato, Cipionato y 17)
ProgestgenosDisp. CIDRAgregado en la racin
Vacas en Anestro y Vaquillonas Prepberes
Inicio de la Actividad Cclica en Vacas Posparto y Vaquillonas Prepberes
Efecto de los Progestgenos sobre la Frecuencia Pulsatil de LHAnderson y col., 1996 (Norgestomet); Imwalle y col., 1998 (MGA)
Progestgenos y PGF para Sincronizar Celos
Folculos persistentes021Das del Ciclo EstralCLFD1
10
8
6
4
2
Tamao del Folculo(mm)
DasPERSISTENCIA FOLICULARAmbiente deprogesteronabajaOvocito de baja fertilidad pulso de LH
Patterson y col. (1989)
CONCEPCION (%) y SERVICIO POR PREEZ SEGUIDO A TRATAMIENTOS CON CIDR x10 DAS y PGF AL RETIRO EN VACAS LECHERAS(Dick y Macmillan, 1990)
Grupos
T
C
N=Vacas
200
182
(%) 1 IA
46
62a
(%) 2 IA
57
65
S/P
1.9
1.6a
a=P
CONTROL DE LA ONDA FOLICULAR(1) El control de la onda folicular es una parte esencial para lograr una sincronizacin precisa en combinacin con una buena fertilidad.
(2) Normalmente comprende induccin de la ovulacin, atresia folicular o luteinizacin folicular. Resultando en la emergencia de una nueva onda folicular. (3) La onda ocurre: 1 da luego de usar GnRH, 3 das luego de usar 5 mg de 17- Beta B, 4 das luego de 1mg BE y 5/6 das luego del CPE y del valerato de estradiol.
Duracin del Tratamiento con Progestgeno: Sincronizacin y Fertilidad
Sincrona del CeloMomento de PGF relacionado al retiro progestgeno
Sincronizacin de la onda Folicular
Sincronizacin de la Onda Folicular
Protocolos IA tiempo fijo (IATF)
Protocolos IA a tiempo fijo con CIDR
Cuatro razones tericas de porque CIDR-Ovsynch debe ser mejor que OvsynchCIDR-Ovsynch previene los celos tempranos en el protocolo Ovsynch.CIDR-Ovsynch es un efectivo tratamiento para anestro.CIDR-Ovsynch es un efectivo tratamiento para quistes foliculares (a pesar de su clasificacin).Verdadero folicularLutealCIDR-Ovsynch funciona en vacas normales.
% Preez en 56 d en Vacas LecherasStevenson y col., JDS 89:2567-2578IATF 16 h despus PGF
Chart1
3048
2451
3125
3938
2430
4737
3338
OVS
OVS+CIDR
Sheet1
OVSOVS+CIDRSeries 3
Illinois30482
Kansas24512
Michigan31253
Missouri39385
Ohio2430
Wisconsin4737
All sites3338
MGA-PGF (14-17 d)
MGA-PGF (14-19 d)
1 14 26 33 1 14 2633 Patterson y col. (2002)MGA 14-19 vs. Selectivo MGA
NoRespuesta001224364860728496108120132144Horas despus PGF1020304050Respuesta en CeloTodas las VacasVacas en celo (%)
Perry y col. (2001)
7-11 SincroEsquema de Tratamiento
Que es un CIDR?Liberacin Interna Controlada de drogaUsa para Control del Ciclo Estral
Vacas de leche y carneVaquillonas de leche y carne
Que es un CIDR?El ingrediente activo es la progesteronaForma natural de la hormonaSe libera por 7 das (o + 8 - 12 d.)En la vaca logra concentraciones en sangre levemente menor a lo normal
Concentraciones de Progesterona en Plasma Durante Tratamiento CIDR
Como se utiliza el CIDR?Insertar CIDR en la vagina (da 0)Al 6to da inyectar PGF (da 6)Al 7mo da retirar el CIDR de la vagina (da 7)Insem al Celo, uno a tres das despus
Ensayos en USA con CIDRLucy y col. (2001)En Colaboracin:Harold Hafs (Rutgers)Ron Butler (Cornell)Mike Fields (Florida)Darrel Kesler (Illinois)Jim Kinder (Nebraska)Matt Lucy (Missouri)Bob Short (Montana)Bill Thatcher (Florida)Bob Wettemann (Oklahoma)Joel Yelich (Florida)
Celo y Preez en Vacas de Carne que se les di Progesterona intravaginal851 vacas de carne con cra al pie en seis lugares: Florida, Illinois, Missouri, Montana, Nebraska and Oklahoma.
Tres tratamientos:Control no tratadoPGF (Lutalyse) Tratadas con CIDR por 7 das con PGF al da 6
Porcentage en Celo - das 1 to 7Vacas de Carne
Fig. 1
3.8117.8913
6.6715.652.02
7.627.88.97
1.94.596.73
5.244.133.59
3.335.961.79
6.193.670
Control
PGF
CIDR+PGF
Dias del Periodo de Servicio
Porcentage en Celo
Fig. 2A
111
0.980.880.94
0.950.840.59
0.890.810.55
0.870.770.5
0.830.710.47
0.80.640.46
0.740.60.46
0.720.60.46
0.660.580.46
0.620.560.46
0.590.550.46
0.570.510.46
0.510.50.46
0.50.450.46
0.480.440.46
0.440.440.46
0.440.40.46
0.430.40.46
0.40.390.46
0.390.390.45
0.390.380.44
0.380.380.39
0.380.370.36
0.380.360.36
0.370.360.36
0.370.360.36
0.360.360.35
0.360.340.35
0.360.340.35
0.340.340.35
0.330.320.34
A
2a
2a
Control
PGF
CIDR+PGF
Proportion of Cows Not Observed in Estrus
Anestrous Cows
Fig. 2B
111
0.930.810.85
0.870.60.38
0.810.510.28
0.80.470.22
0.770.470.19
0.750.460.18
0.720.440.18
0.70.430.18
0.660.430.18
0.630.430.18
0.60.40.18
0.570.390.18
0.540.390.18
0.490.390.18
0.470.390.18
0.430.340.18
0.380.290.18
0.360.280.18
0.330.260.18
0.290.220.18
0.280.210.16
0.270.180.14
0.260.170.13
0.250.170.11
0.240.170.1
0.240.140.09
0.240.120.09
0.240.120.09
0.220.120.09
0.20.120.09
0.180.120.09
B
Control
PGF
CIDR+PGF
Day of Breeding Period
Proportion of Cows Not Observed in Estrus
Cyclic Cows
Fig. 3A
111
0.990.920.96
0.970.910.76
0.960.910.74
0.960.880.71
0.920.850.69
0.90.80.69
0.850.770.69
0.840.760.69
0.790.750.69
0.770.730.69
0.750.720.69
0.740.70.69
0.70.690.69
0.70.660.69
0.680.660.69
0.680.660.69
0.670.640.69
0.660.640.69
0.640.630.69
0.640.630.69
0.640.630.66
0.640.610.62
0.640.610.56
0.620.60.56
0.610.590.56
0.610.590.55
0.610.590.54
0.610.560.54
0.610.550.54
0.590.550.54
0.580.530.54
A
2a
2a
Control
PGF
CIDR+PGF
Proportion of Cows Not Pregnant
Anestrous Cows
Fig. 3B
111
0.950.860.92
0.920.720.6
0.890.660.54
0.880.630.49
0.880.630.48
0.860.630.48
0.840.610.48
0.830.610.48
0.80.60.48
0.780.60.48
0.760.590.47
0.740.590.47
0.730.590.47
0.690.590.47
0.690.590.47
0.660.550.47
0.610.510.47
0.60.50.47
0.580.490.47
0.580.470.47
0.550.460.45
0.540.430.43
0.520.40.4
0.50.390.36
0.480.390.32
0.480.370.3
0.480.350.3
0.450.350.29
0.440.350.29
0.440.350.29
0.420.350.29
B
Control
PGF
CIDR+PGF
Day of Breeding Period
Proportion of Cows Not Pregnant
Cyclic Cows
Fig. 4
4.9220.2214.84
5.4611.2452.75
6.014.4910.99
6.565.061.1
4.372.811.1
2.732.810.55
7.12.810.55
2a
2a
Control
PGF
CIDR+PGF
Day of Breeding Period
Percentage in Estrus
Fig. 5A
111
0.990.930.91
0.970.890.58
0.930.890.52
0.880.870.51
0.860.830.5
0.860.790.5
0.790.770.49
0.780.760.49
0.740.750.49
0.730.740.48
0.690.740.48
0.680.730.48
0.670.730.48
0.660.720.47
0.650.720.46
0.640.710.45
0.640.670.44
0.610.650.42
0.610.650.38
0.590.620.35
0.550.620.34
0.530.620.34
0.510.620.31
0.50.60.3
0.50.590.3
0.50.590.3
0.50.590.3
0.490.590.29
0.470.560.29
0.470.550.29
0.460.550.29
A
2a
2a
Control
PGF
CIDR+PGF
Proportion of Heifers Not Observed in Estrus
Prepubertal Heifers
Fig. 5B
111
0.920.790.84
0.870.680.32
0.830.630.2
0.780.580.19
0.740.580.19
0.70.570.18
0.660.550.18
0.650.540.18
0.560.540.17
0.520.540.17
0.50.540.17
0.450.520.17
0.420.480.17
0.40.410.17
0.370.390.17
0.320.350.17
0.280.30.16
0.240.240.16
0.220.210.16
0.190.190.16
0.180.180.11
0.170.170.1
0.170.150.09
0.170.150.09
0.160.140.09
0.150.140.09
0.150.130.08
0.140.130.08
0.130.120.08
0.130.120.08
0.130.120.08
B
Control
PGF
CIDR+PGF
Day of Breeding Period
Proportion of Heifers Not Observed in Estrus
Cyclic Heifers
Fig. 6A
111
10.940.92
0.980.940.73
0.940.940.72
0.940.930.72
0.910.90.7
0.910.870.7
0.880.860.69
0.880.860.69
0.850.850.68
0.850.850.68
0.820.850.68
0.820.840.68
0.810.840.68
0.80.830.68
0.790.830.67
0.790.830.66
0.790.820.66
0.780.820.66
0.780.810.63
0.770.810.61
0.730.810.59
0.720.810.57
0.720.810.54
0.720.780.53
0.720.760.53
0.720.750.53
0.720.750.52
0.710.750.51
0.690.750.5
0.690.750.5
0.690.750.5
A
2a
2a
Control
PGF
CIDR+PGF
Proportion of Heifers Not Pregnant
Prepubertal Heifers
Fig. 6B
111
0.960.860.91
0.920.820.58
0.910.80.51
0.890.790.5
0.870.790.5
0.850.780.49
0.820.770.49
0.810.770.49
0.760.760.48
0.730.750.48
0.730.750.48
0.690.740.48
0.660.730.48
0.620.70.48
0.60.680.47
0.570.680.47
0.520.640.47
0.510.60.47
0.480.560.47
0.470.540.46
0.450.510.42
0.440.490.4
0.430.480.38
0.420.480.37
0.40.460.35
0.390.450.34
0.380.450.32
0.370.450.32
0.360.440.32
0.360.440.32
0.360.440.32
B
Control
PGF
CIDR+PGF
Day of Breeding Period
Proportion of Heifers Not Pregnant
Cyclic Heifers
Fig. 7
43.0914.78
16.2657.39
4.8817.39
2.444.35
1.630
0.810
0.810
2a
2a
PGF
CIDR+PGF
Day of Breeding Period
Percentage in Estrus
Fig. 8A
11
0.620.86
0.470.32
0.430.16
0.410.11
0.390.11
0.380.11
0.380.11
0.380.11
0.370.1
0.360.1
0.360.1
0.350.1
0.340.1
0.320.1
0.310.1
0.30.1
0.270.1
0.220.1
0.20.09
0.190.09
0.170.07
0.160.07
0.140.07
0.130.07
0.130.07
0.130.07
0.130.07
0.130.06
0.130.06
0.110.06
0.110.06
A
2a
2a
PGF
CIDR+PGF
Proportion of Heifers Not Observed in Estrus
Dairy Heifers
Fig. 8B
11
0.750.94
0.660.64
0.620.55
0.610.53
0.60.53
0.60.53
0.590.53
0.590.53
0.590.53
0.590.53
0.590.52
0.590.52
0.580.52
0.560.52
0.560.52
0.550.52
0.540.52
0.510.52
0.50.5
0.490.48
0.460.47
0.460.45
0.450.44
0.450.42
0.430.42
0.430.42
0.430.42
0.430.41
0.430.41
0.430.41
0.430.41
B
PGF
CIDR+PGF
Day of Breeding Period
Proportion of Heifers Not Pregnant
Dairy Heifers
Int to estrus data
1234567
Control3.816.677.621.95.243.336.19
PGF17.8915.67.84.594.135.963.67
CIDR+PGF1352.028.976.733.591.790
1234567
Control4.925.466.016.564.372.737.1
PGF20.2211.244.495.062.812.812.81
CIDR+PGF14.8452.7510.991.11.10.550.55
1234567
PGF43.0916.264.882.441.630.810.81
CIDR+PGF14.7857.3917.394.35000
Survival Data
Anestrus Cows - IFS
012345678910111213141516171819202122232425262728293031
Control10.980.950.890.870.830.80.740.720.660.620.590.570.510.50.480.440.440.430.40.390.390.380.380.380.370.370.360.360.360.340.33
PGF10.880.840.810.770.710.640.60.60.580.560.550.510.50.450.440.440.40.40.390.390.380.380.370.360.360.360.360.340.340.340.32
CIDR+PGF10.940.590.550.50.470.460.460.460.460.460.460.460.460.460.460.460.460.460.460.450.440.390.360.360.360.360.350.350.350.350.34
Cyclic Cows - IFS
012345678910111213141516171819202122232425262728293031
Control10.930.870.810.80.770.750.720.70.660.630.60.570.540.490.470.430.380.360.330.290.280.270.260.250.240.240.240.240.220.20.18
PGF10.810.60.510.470.470.460.440.430.430.430.40.390.390.390.390.340.290.280.260.220.210.180.170.170.170.140.120.120.120.120.12
CIDR+PGF10.850.380.280.220.190.180.180.180.180.180.180.180.180.180.180.180.180.180.180.180.160.140.130.110.10.090.090.090.090.090.09
Anestrus Cows - Preg
012345678910111213141516171819202122232425262728293031
Control10.990.970.960.960.920.90.850.840.790.770.750.740.70.70.680.680.670.660.640.640.640.640.640.620.610.610.610.610.610.590.58
PGF10.920.910.910.880.850.80.770.760.750.730.720.70.690.660.660.660.640.640.630.630.630.610.610.60.590.590.590.560.550.550.53
CIDR+PGF10.960.760.740.710.690.690.690.690.690.690.690.690.690.690.690.690.690.690.690.690.660.620.560.560.560.550.540.540.540.540.54
Cyclic Cows - Preg
012345678910111213141516171819202122232425262728293031
Control10.950.920.890.880.880.860.840.830.80.780.760.740.730.690.690.660.610.60.580.580.550.540.520.50.480.480.480.450.440.440.42
PGF10.860.720.660.630.630.630.610.610.60.60.590.590.590.590.590.550.510.50.490.470.460.430.40.390.390.370.350.350.350.350.35
CIDR+PGF10.920.60.540.490.480.480.480.480.480.480.470.470.470.470.470.470.470.470.470.470.450.430.40.360.320.30.30.290.290.290.29
Prepubertal heifers - IFS
012345678910111213141516171819202122232425262728293031
Control10.990.970.930.880.860.860.790.780.740.730.690.680.670.660.650.640.640.610.610.590.550.530.510.50.50.50.50.490.470.470.46
PGF10.930.890.890.870.830.790.770.760.750.740.740.730.730.720.720.710.670.650.650.620.620.620.620.60.590.590.590.590.560.550.55
CIDR+PGF10.910.580.520.510.50.50.490.490.490.480.480.480.480.470.460.450.440.420.380.350.340.340.310.30.30.30.30.290.290.290.29
Cyclic heifers - IFS
012345678910111213141516171819202122232425262728293031
Control10.920.870.830.780.740.70.660.650.560.520.50.450.420.40.370.320.280.240.220.190.180.170.170.170.160.150.150.140.130.130.13
PGF10.790.680.630.580.580.570.550.540.540.540.540.520.480.410.390.350.30.240.210.190.180.170.150.150.140.140.130.130.120.120.12
CIDR+PGF10.840.320.20.190.190.180.180.180.170.170.170.170.170.170.170.170.160.160.160.160.110.10.090.090.090.090.080.080.080.080.08
Prepubertal heifers - Preg
012345678910111213141516171819202122232425262728293031
Control110.980.940.940.910.910.880.880.850.850.820.820.810.80.790.790.790.780.780.770.730.720.720.720.720.720.720.710.690.690.69
PGF10.940.940.940.930.90.870.860.860.850.850.850.840.840.830.830.830.820.820.810.810.810.810.810.780.760.750.750.750.750.750.75
CIDR+PGF10.920.730.720.720.70.70.690.690.680.680.680.680.680.680.670.660.660.660.630.610.590.570.540.530.530.530.520.510.50.50.5
Cyclic heifers - Preg
012345678910111213141516171819202122232425262728293031
Control10.960.920.910.890.870.850.820.810.760.730.730.690.660.620.60.570.520.510.480.470.450.440.430.420.40.390.380.370.360.360.36
PGF10.860.820.80.790.790.780.770.770.760.750.750.740.730.70.680.680.640.60.560.540.510.490.480.480.460.450.450.450.440.440.44
CIDR+PGF10.910.580.510.50.50.490.490.490.480.480.480.480.480.480.470.470.470.470.470.460.420.40.380.370.350.340.320.320.320.320.32
Dairy IFS
012345678910111213141516171819202122232425262728293031
PGF10.620.470.430.410.390.380.380.380.370.360.360.350.340.320.310.30.270.220.20.190.170.160.140.130.130.130.130.130.130.110.11
CIDR+PGF10.860.320.160.110.110.110.110.110.10.10.10.10.10.10.10.10.10.10.090.090.070.070.070.070.070.070.070.060.060.060.06
Dairy Preg
012345678910111213141516171819202122232425262728293031
PGF10.750.660.620.610.60.60.590.590.590.590.590.590.580.560.560.550.540.510.50.490.460.460.450.450.430.430.430.430.430.430.43
CIDR+PGF10.940.640.550.530.530.530.530.530.530.530.520.520.520.520.520.520.520.520.50.480.470.450.440.420.420.420.420.410.410.410.41
Sheet3
Intervalo al CeloVacas Anestro
Fig. 1
3.8117.8913
6.6715.652.02
7.627.88.97
1.94.596.73
5.244.133.59
3.335.961.79
6.193.670
2a
2a
Control
PGF
CIDR+PGF
Day of Breeding Period
Percentage in Estrus
Fig. 2A
111
0.980.880.94
0.950.840.59
0.890.810.55
0.870.770.5
0.830.710.47
0.80.640.46
0.740.60.46
0.720.60.46
0.660.580.46
0.620.560.46
0.590.550.46
0.570.510.46
0.510.50.46
0.50.450.46
0.480.440.46
0.440.440.46
0.440.40.46
0.430.40.46
0.40.390.46
0.390.390.45
0.390.380.44
0.380.380.39
0.380.370.36
0.380.360.36
0.370.360.36
0.370.360.36
0.360.360.35
0.360.340.35
0.360.340.35
0.340.340.35
0.330.320.34
Control
PGF
CIDR+PGF
Dias del Periodo de Servicio
Proporcion de Vacas No Observadas en Celo
Fig. 2B
111
0.930.810.85
0.870.60.38
0.810.510.28
0.80.470.22
0.770.470.19
0.750.460.18
0.720.440.18
0.70.430.18
0.660.430.18
0.630.430.18
0.60.40.18
0.570.390.18
0.540.390.18
0.490.390.18
0.470.390.18
0.430.340.18
0.380.290.18
0.360.280.18
0.330.260.18
0.290.220.18
0.280.210.16
0.270.180.14
0.260.170.13
0.250.170.11
0.240.170.1
0.240.140.09
0.240.120.09
0.240.120.09
0.220.120.09
0.20.120.09
0.180.120.09
B
Control
PGF
CIDR+PGF
Day of Breeding Period
Proportion of Cows Not Observed in Estrus
Cyclic Cows
Fig. 3A
111
0.990.920.96
0.970.910.76
0.960.910.74
0.960.880.71
0.920.850.69
0.90.80.69
0.850.770.69
0.840.760.69
0.790.750.69
0.770.730.69
0.750.720.69
0.740.70.69
0.70.690.69
0.70.660.69
0.680.660.69
0.680.660.69
0.670.640.69
0.660.640.69
0.640.630.69
0.640.630.69
0.640.630.66
0.640.610.62
0.640.610.56
0.620.60.56
0.610.590.56
0.610.590.55
0.610.590.54
0.610.560.54
0.610.550.54
0.590.550.54
0.580.530.54
A
2a
2a
Control
PGF
CIDR+PGF
Proportion of Cows Not Pregnant
Anestrous Cows
Fig. 3B
111
0.950.860.92
0.920.720.6
0.890.660.54
0.880.630.49
0.880.630.48
0.860.630.48
0.840.610.48
0.830.610.48
0.80.60.48
0.780.60.48
0.760.590.47
0.740.590.47
0.730.590.47
0.690.590.47
0.690.590.47
0.660.550.47
0.610.510.47
0.60.50.47
0.580.490.47
0.580.470.47
0.550.460.45
0.540.430.43
0.520.40.4
0.50.390.36
0.480.390.32
0.480.370.3
0.480.350.3
0.450.350.29
0.440.350.29
0.440.350.29
0.420.350.29
B
Control
PGF
CIDR+PGF
Day of Breeding Period
Proportion of Cows Not Pregnant
Cyclic Cows
Fig. 4
4.9220.2214.84
5.4611.2452.75
6.014.4910.99
6.565.061.1
4.372.811.1
2.732.810.55
7.12.810.55
2a
2a
Control
PGF
CIDR+PGF
Day of Breeding Period
Percentage in Estrus
Fig. 5A
111
0.990.930.91
0.970.890.58
0.930.890.52
0.880.870.51
0.860.830.5
0.860.790.5
0.790.770.49
0.780.760.49
0.740.750.49
0.730.740.48
0.690.740.48
0.680.730.48
0.670.730.48
0.660.720.47
0.650.720.46
0.640.710.45
0.640.670.44
0.610.650.42
0.610.650.38
0.590.620.35
0.550.620.34
0.530.620.34
0.510.620.31
0.50.60.3
0.50.590.3
0.50.590.3
0.50.590.3
0.490.590.29
0.470.560.29
0.470.550.29
0.460.550.29
A
2a
2a
Control
PGF
CIDR+PGF
Proportion of Heifers Not Observed in Estrus
Prepubertal Heifers
Fig. 5B
111
0.920.790.84
0.870.680.32
0.830.630.2
0.780.580.19
0.740.580.19
0.70.570.18
0.660.550.18
0.650.540.18
0.560.540.17
0.520.540.17
0.50.540.17
0.450.520.17
0.420.480.17
0.40.410.17
0.370.390.17
0.320.350.17
0.280.30.16
0.240.240.16
0.220.210.16
0.190.190.16
0.180.180.11
0.170.170.1
0.170.150.09
0.170.150.09
0.160.140.09
0.150.140.09
0.150.130.08
0.140.130.08
0.130.120.08
0.130.120.08
0.130.120.08
B
Control
PGF
CIDR+PGF
Day of Breeding Period
Proportion of Heifers Not Observed in Estrus
Cyclic Heifers
Fig. 6A
111
10.940.92
0.980.940.73
0.940.940.72
0.940.930.72
0.910.90.7
0.910.870.7
0.880.860.69
0.880.860.69
0.850.850.68
0.850.850.68
0.820.850.68
0.820.840.68
0.810.840.68
0.80.830.68
0.790.830.67
0.790.830.66
0.790.820.66
0.780.820.66
0.780.810.63
0.770.810.61
0.730.810.59
0.720.810.57
0.720.810.54
0.720.780.53
0.720.760.53
0.720.750.53
0.720.750.52
0.710.750.51
0.690.750.5
0.690.750.5
0.690.750.5
A
2a
2a
Control
PGF
CIDR+PGF
Proportion of Heifers Not Pregnant
Prepubertal Heifers
Fig. 6B
111
0.960.860.91
0.920.820.58
0.910.80.51
0.890.790.5
0.870.790.5
0.850.780.49
0.820.770.49
0.810.770.49
0.760.760.48
0.730.750.48
0.730.750.48
0.690.740.48
0.660.730.48
0.620.70.48
0.60.680.47
0.570.680.47
0.520.640.47
0.510.60.47
0.480.560.47
0.470.540.46
0.450.510.42
0.440.490.4
0.430.480.38
0.420.480.37
0.40.460.35
0.390.450.34
0.380.450.32
0.370.450.32
0.360.440.32
0.360.440.32
0.360.440.32
B
Control
PGF
CIDR+PGF
Day of Breeding Period
Proportion of Heifers Not Pregnant
Cyclic Heifers
Fig. 7
43.0914.78
16.2657.39
4.8817.39
2.444.35
1.630
0.810
0.810
2a
2a
PGF
CIDR+PGF
Day of Breeding Period
Percentage in Estrus
Fig. 8A
11
0.620.86
0.470.32
0.430.16
0.410.11
0.390.11
0.380.11
0.380.11
0.380.11
0.370.1
0.360.1
0.360.1
0.350.1
0.340.1
0.320.1
0.310.1
0.30.1
0.270.1
0.220.1
0.20.09
0.190.09
0.170.07
0.160.07
0.140.07
0.130.07
0.130.07
0.130.07
0.130.07
0.130.06
0.130.06
0.110.06
0.110.06
A
2a
2a
PGF
CIDR+PGF
Proportion of Heifers Not Observed in Estrus
Dairy Heifers
Fig. 8B
11
0.750.94
0.660.64
0.620.55
0.610.53
0.60.53
0.60.53
0.590.53
0.590.53
0.590.53
0.590.53
0.590.52
0.590.52
0.580.52
0.560.52
0.560.52
0.550.52
0.540.52
0.510.52
0.50.5
0.490.48
0.460.47
0.460.45
0.450.44
0.450.42
0.430.42
0.430.42
0.430.42
0.430.41
0.430.41
0.430.41
0.430.41
B
PGF
CIDR+PGF
Day of Breeding Period
Proportion of Heifers Not Pregnant
Dairy Heifers
Int to estrus data
1234567
Control3.816.677.621.95.243.336.19
PGF17.8915.67.84.594.135.963.67
CIDR+PGF1352.028.976.733.591.790
1234567
Control4.925.466.016.564.372.737.1
PGF20.2211.244.495.062.812.812.81
CIDR+PGF14.8452.7510.991.11.10.550.55
1234567
PGF43.0916.264.882.441.630.810.81
CIDR+PGF14.7857.3917.394.35000
Survival Data
Anestrus Cows - IFS
012345678910111213141516171819202122232425262728293031
Control10.980.950.890.870.830.80.740.720.660.620.590.570.510.50.480.440.440.430.40.390.390.380.380.380.370.370.360.360.360.340.33
PGF10.880.840.810.770.710.640.60.60.580.560.550.510.50.450.440.440.40.40.390.390.380.380.370.360.360.360.360.340.340.340.32
CIDR+PGF10.940.590.550.50.470.460.460.460.460.460.460.460.460.460.460.460.460.460.460.450.440.390.360.360.360.360.350.350.350.350.34
Cyclic Cows - IFS
012345678910111213141516171819202122232425262728293031
Control10.930.870.810.80.770.750.720.70.660.630.60.570.540.490.470.430.380.360.330.290.280.270.260.250.240.240.240.240.220.20.18
PGF10.810.60.510.470.470.460.440.430.430.430.40.390.390.390.390.340.290.280.260.220.210.180.170.170.170.140.120.120.120.120.12
CIDR+PGF10.850.380.280.220.190.180.180.180.180.180.180.180.180.180.180.180.180.180.180.180.160.140.130.110.10.090.090.090.090.090.09
Anestrus Cows - Preg
012345678910111213141516171819202122232425262728293031
Control10.990.970.960.960.920.90.850.840.790.770.750.740.70.70.680.680.670.660.640.640.640.640.640.620.610.610.610.610.610.590.58
PGF10.920.910.910.880.850.80.770.760.750.730.720.70.690.660.660.660.640.640.630.630.630.610.610.60.590.590.590.560.550.550.53
CIDR+PGF10.960.760.740.710.690.690.690.690.690.690.690.690.690.690.690.690.690.690.690.690.660.620.560.560.560.550.540.540.540.540.54
Cyclic Cows - Preg
012345678910111213141516171819202122232425262728293031
Control10.950.920.890.880.880.860.840.830.80.780.760.740.730.690.690.660.610.60.580.580.550.540.520.50.480.480.480.450.440.440.42
PGF10.860.720.660.630.630.630.610.610.60.60.590.590.590.590.590.550.510.50.490.470.460.430.40.390.390.370.350.350.350.350.35
CIDR+PGF10.920.60.540.490.480.480.480.480.480.480.470.470.470.470.470.470.470.470.470.470.450.430.40.360.320.30.30.290.290.290.29
Prepubertal heifers - IFS
012345678910111213141516171819202122232425262728293031
Control10.990.970.930.880.860.860.790.780.740.730.690.680.670.660.650.640.640.610.610.590.550.530.510.50.50.50.50.490.470.470.46
PGF10.930.890.890.870.830.790.770.760.750.740.740.730.730.720.720.710.670.650.650.620.620.620.620.60.590.590.590.590.560.550.55
CIDR+PGF10.910.580.520.510.50.50.490.490.490.480.480.480.480.470.460.450.440.420.380.350.340.340.310.30.30.30.30.290.290.290.29
Cyclic heifers - IFS
012345678910111213141516171819202122232425262728293031
Control10.920.870.830.780.740.70.660.650.560.520.50.450.420.40.370.320.280.240.220.190.180.170.170.170.160.150.150.140.130.130.13
PGF10.790.680.630.580.580.570.550.540.540.540.540.520.480.410.390.350.30.240.210.190.180.170.150.150.140.140.130.130.120.120.12
CIDR+PGF10.840.320.20.190.190.180.180.180.170.170.170.170.170.170.170.170.160.160.160.160.110.10.090.090.090.090.080.080.080.080.08
Prepubertal heifers - Preg
012345678910111213141516171819202122232425262728293031
Control110.980.940.940.910.910.880.880.850.850.820.820.810.80.790.790.790.780.780.770.730.720.720.720.720.720.720.710.690.690.69
PGF10.940.940.940.930.90.870.860.860.850.850.850.840.840.830.830.830.820.820.810.810.810.810.810.780.760.750.750.750.750.750.75
CIDR+PGF10.920.730.720.720.70.70.690.690.680.680.680.680.680.680.670.660.660.660.630.610.590.570.540.530.530.530.520.510.50.50.5
Cyclic heifers - Preg
012345678910111213141516171819202122232425262728293031
Control10.960.920.910.890.870.850.820.810.760.730.730.690.660.620.60.570.520.510.480.470.450.440.430.420.40.390.380.370.360.360.36
PGF10.860.820.80.790.790.780.770.770.760.750.750.740.730.70.680.680.640.60.560.540.510.490.480.480.460.450.450.450.440.440.44
CIDR+PGF10.910.580.510.50.50.490.490.490.480.480.480.480.480.480.470.470.470.470.470.460.420.40.380.370.350.340.320.320.320.320.32
Dairy IFS
012345678910111213141516171819202122232425262728293031
PGF10.620.470.430.410.390.380.380.380.370.360.360.350.340.320.310.30.270.220.20.190.170.160.140.130.130.130.130.130.130.110.11
CIDR+PGF10.860.320.160.110.110.110.110.110.10.10.10.10.10.10.10.10.10.10.090.090.070.070.070.070.070.070.070.060.060.060.06
Dairy Preg
012345678910111213141516171819202122232425262728293031
PGF10.750.660.620.610.60.60.590.590.590.590.590.590.580.560.560.550.540.510.50.490.460.460.450.450.430.430.430.430.430.430.43
CIDR+PGF10.940.640.550.530.530.530.530.530.530.530.520.520.520.520.520.520.520.520.50.480.470.450.440.420.420.420.420.410.410.410.41
Sheet3
Intervalo al CeloVacas Cclicas
Fig. 1
3.8117.8913
6.6715.652.02
7.627.88.97
1.94.596.73
5.244.133.59
3.335.961.79
6.193.670
2a
2a
Control
PGF
CIDR+PGF
Day of Breeding Period
Percentage in Estrus
Fig. 2A
111
0.930.810.85
0.870.60.38
0.810.510.28
0.80.470.22
0.770.470.19
0.750.460.18
0.720.440.18
0.70.430.18
0.660.430.18
0.630.430.18
0.60.40.18
0.570.390.18
0.540.390.18
0.490.390.18
0.470.390.18
0.430.340.18
0.380.290.18
0.360.280.18
0.330.260.18
0.290.220.18
0.280.210.16
0.270.180.14
0.260.170.13
0.250.170.11
0.240.170.1
0.240.140.09
0.240.120.09
0.240.120.09
0.220.120.09
0.20.120.09
0.180.120.09
Control
PGF
CIDR+PGF
Dias del Periodo de Servicio
Proporcion de Vacas No Observadas en Celo
Fig. 2B
111
0.930.810.85
0.870.60.38
0.810.510.28
0.80.470.22
0.770.470.19
0.750.460.18
0.720.440.18
0.70.430.18
0.660.430.18
0.630.430.18
0.60.40.18
0.570.390.18
0.540.390.18
0.490.390.18
0.470.390.18
0.430.340.18
0.380.290.18
0.360.280.18
0.330.260.18
0.290.220.18
0.280.210.16
0.270.180.14
0.260.170.13
0.250.170.11
0.240.170.1
0.240.140.09
0.240.120.09
0.240.120.09
0.220.120.09
0.20.120.09
0.180.120.09
B
Control
PGF
CIDR+PGF
Day of Breeding Period
Proportion of Cows Not Observed in Estrus
Cyclic Cows
Fig. 3A
111
0.990.920.96
0.970.910.76
0.960.910.74
0.960.880.71
0.920.850.69
0.90.80.69
0.850.770.69
0.840.760.69
0.790.750.69
0.770.730.69
0.750.720.69
0.740.70.69
0.70.690.69
0.70.660.69
0.680.660.69
0.680.660.69
0.670.640.69
0.660.640.69
0.640.630.69
0.640.630.69
0.640.630.66
0.640.610.62
0.640.610.56
0.620.60.56
0.610.590.56
0.610.590.55
0.610.590.54
0.610.560.54
0.610.550.54
0.590.550.54
0.580.530.54
A
2a
2a
Control
PGF
CIDR+PGF
Proportion of Cows Not Pregnant
Anestrous Cows
Fig. 3B
111
0.950.860.92
0.920.720.6
0.890.660.54
0.880.630.49
0.880.630.48
0.860.630.48
0.840.610.48
0.830.610.48
0.80.60.48
0.780.60.48
0.760.590.47
0.740.590.47
0.730.590.47
0.690.590.47
0.690.590.47
0.660.550.47
0.610.510.47
0.60.50.47
0.580.490.47
0.580.470.47
0.550.460.45
0.540.430.43
0.520.40.4
0.50.390.36
0.480.390.32
0.480.370.3
0.480.350.3
0.450.350.29
0.440.350.29
0.440.350.29
0.420.350.29
B
Control
PGF
CIDR+PGF
Day of Breeding Period
Proportion of Cows Not Pregnant
Cyclic Cows
Fig. 4
4.9220.2214.84
5.4611.2452.75
6.014.4910.99
6.565.061.1
4.372.811.1
2.732.810.55
7.12.810.55
2a
2a
Control
PGF
CIDR+PGF
Day of Breeding Period
Percentage in Estrus
Fig. 5A
111
0.990.930.91
0.970.890.58
0.930.890.52
0.880.870.51
0.860.830.5
0.860.790.5
0.790.770.49
0.780.760.49
0.740.750.49
0.730.740.48
0.690.740.48
0.680.730.48
0.670.730.48
0.660.720.47
0.650.720.46
0.640.710.45
0.640.670.44
0.610.650.42
0.610.650.38
0.590.620.35
0.550.620.34
0.530.620.34
0.510.620.31
0.50.60.3
0.50.590.3
0.50.590.3
0.50.590.3
0.490.590.29
0.470.560.29
0.470.550.29
0.460.550.29
A
2a
2a
Control
PGF
CIDR+PGF
Proportion of Heifers Not Observed in Estrus
Prepubertal Heifers
Fig. 5B
111
0.920.790.84
0.870.680.32
0.830.630.2
0.780.580.19
0.740.580.19
0.70.570.18
0.660.550.18
0.650.540.18
0.560.540.17
0.520.540.17
0.50.540.17
0.450.520.17
0.420.480.17
0.40.410.17
0.370.390.17
0.320.350.17
0.280.30.16
0.240.240.16
0.220.210.16
0.190.190.16
0.180.180.11
0.170.170.1
0.170.150.09
0.170.150.09
0.160.140.09
0.150.140.09
0.150.130.08
0.140.130.08
0.130.120.08
0.130.120.08
0.130.120.08
B
Control
PGF
CIDR+PGF
Day of Breeding Period
Proportion of Heifers Not Observed in Estrus
Cyclic Heifers
Fig. 6A
111
10.940.92
0.980.940.73
0.940.940.72
0.940.930.72
0.910.90.7
0.910.870.7
0.880.860.69
0.880.860.69
0.850.850.68
0.850.850.68
0.820.850.68
0.820.840.68
0.810.840.68
0.80.830.68
0.790.830.67
0.790.830.66
0.790.820.66
0.780.820.66
0.780.810.63
0.770.810.61
0.730.810.59
0.720.810.57
0.720.810.54
0.720.780.53
0.720.760.53
0.720.750.53
0.720.750.52
0.710.750.51
0.690.750.5
0.690.750.5
0.690.750.5
A
2a
2a
Control
PGF
CIDR+PGF
Proportion of Heifers Not Pregnant
Prepubertal Heifers
Fig. 6B
111
0.960.860.91
0.920.820.58
0.910.80.51
0.890.790.5
0.870.790.5
0.850.780.49
0.820.770.49
0.810.770.49
0.760.760.48
0.730.750.48
0.730.750.48
0.690.740.48
0.660.730.48
0.620.70.48
0.60.680.47
0.570.680.47
0.520.640.47
0.510.60.47
0.480.560.47
0.470.540.46
0.450.510.42
0.440.490.4
0.430.480.38
0.420.480.37
0.40.460.35
0.390.450.34
0.380.450.32
0.370.450.32
0.360.440.32
0.360.440.32
0.360.440.32
B
Control
PGF
CIDR+PGF
Day of Breeding Period
Proportion of Heifers Not Pregnant
Cyclic Heifers
Fig. 7
43.0914.78
16.2657.39
4.8817.39
2.444.35
1.630
0.810
0.810
2a
2a
PGF
CIDR+PGF
Day of Breeding Period
Percentage in Estrus
Fig. 8A
11
0.620.86
0.470.32
0.430.16
0.410.11
0.390.11
0.380.11
0.380.11
0.380.11
0.370.1
0.360.1
0.360.1
0.350.1
0.340.1
0.320.1
0.310.1
0.30.1
0.270.1
0.220.1
0.20.09
0.190.09
0.170.07
0.160.07
0.140.07
0.130.07
0.130.07
0.130.07
0.130.07
0.130.06
0.130.06
0.110.06
0.110.06
A
2a
2a
PGF
CIDR+PGF
Proportion of Heifers Not Observed in Estrus
Dairy Heifers
Fig. 8B
11
0.750.94
0.660.64
0.620.55
0.610.53
0.60.53
0.60.53
0.590.53
0.590.53
0.590.53
0.590.53
0.590.52
0.590.52
0.580.52
0.560.52
0.560.52
0.550.52
0.540.52
0.510.52
0.50.5
0.490.48
0.460.47
0.460.45
0.450.44
0.450.42
0.430.42
0.430.42
0.430.42
0.430.41
0.430.41
0.430.41
0.430.41
B
PGF
CIDR+PGF
Day of Breeding Period
Proportion of Heifers Not Pregnant
Dairy Heifers
Int to estrus data
1234567
Control3.816.677.621.95.243.336.19
PGF17.8915.67.84.594.135.963.67
CIDR+PGF1352.028.976.733.591.790
1234567
Control4.925.466.016.564.372.737.1
PGF20.2211.244.495.062.812.812.81
CIDR+PGF14.8452.7510.991.11.10.550.55
1234567
PGF43.0916.264.882.441.630.810.81
CIDR+PGF14.7857.3917.394.35000
Survival Data
Anestrus Cows - IFS
012345678910111213141516171819202122232425262728293031
Control10.980.950.890.870.830.80.740.720.660.620.590.570.510.50.480.440.440.430.40.390.390.380.380.380.370.370.360.360.360.340.33
PGF10.880.840.810.770.710.640.60.60.580.560.550.510.50.450.440.440.40.40.390.390.380.380.370.360.360.360.360.340.340.340.32
CIDR+PGF10.940.590.550.50.470.460.460.460.460.460.460.460.460.460.460.460.460.460.460.450.440.390.360.360.360.360.350.350.350.350.34
Cyclic Cows - IFS
012345678910111213141516171819202122232425262728293031
Control10.930.870.810.80.770.750.720.70.660.630.60.570.540.490.470.430.380.360.330.290.280.270.260.250.240.240.240.240.220.20.18
PGF10.810.60.510.470.470.460.440.430.430.430.40.390.390.390.390.340.290.280.260.220.210.180.170.170.170.140.120.120.120.120.12
CIDR+PGF10.850.380.280.220.190.180.180.180.180.180.180.180.180.180.180.180.180.180.180.180.160.140.130.110.10.090.090.090.090.090.09
Anestrus Cows - Preg
012345678910111213141516171819202122232425262728293031
Control10.990.970.960.960.920.90.850.840.790.770.750.740.70.70.680.680.670.660.640.640.640.640.640.620.610.610.610.610.610.590.58
PGF10.920.910.910.880.850.80.770.760.750.730.720.70.690.660.660.660.640.640.630.630.630.610.610.60.590.590.590.560.550.550.53
CIDR+PGF10.960.760.740.710.690.690.690.690.690.690.690.690.690.690.690.690.690.690.690.690.660.620.560.560.560.550.540.540.540.540.54
Cyclic Cows - Preg
012345678910111213141516171819202122232425262728293031
Control10.950.920.890.880.880.860.840.830.80.780.760.740.730.690.690.660.610.60.580.580.550.540.520.50.480.480.480.450.440.440.42
PGF10.860.720.660.630.630.630.610.610.60.60.590.590.590.590.590.550.510.50.490.470.460.430.40.390.390.370.350.350.350.350.35
CIDR+PGF10.920.60.540.490.480.480.480.480.480.480.470.470.470.470.470.470.470.470.470.470.450.430.40.360.320.30.30.290.290.290.29
Prepubertal heifers - IFS
012345678910111213141516171819202122232425262728293031
Control10.990.970.930.880.860.860.790.780.740.730.690.680.670.660.650.640.640.610.610.590.550.530.510.50.50.50.50.490.470.470.46
PGF10.930.890.890.870.830.790.770.760.750.740.740.730.730.720.720.710.670.650.650.620.620.620.620.60.590.590.590.590.560.550.55
CIDR+PGF10.910.580.520.510.50.50.490.490.490.480.480.480.480.470.460.450.440.420.380.350.340.340.310.30.30.30.30.290.290.290.29
Cyclic heifers - IFS
012345678910111213141516171819202122232425262728293031
Control10.920.870.830.780.740.70.660.650.560.520.50.450.420.40.370.320.280.240.220.190.180.170.170.170.160.150.150.140.130.130.13
PGF10.790.680.630.580.580.570.550.540.540.540.540.520.480.410.390.350.30.240.210.190.180.170.150.150.140.140.130.130.120.120.12
CIDR+PGF10.840.320.20.190.190.180.180.180.170.170.170.170.170.170.170.170.160.160.160.160.110.10.090.090.090.090.080.080.080.080.08
Prepubertal heifers - Preg
012345678910111213141516171819202122232425262728293031
Control110.980.940.940.910.910.880.880.850.850.820.820.810.80.790.790.790.780.780.770.730.720.720.720.720.720.720.710.690.690.69
PGF10.940.940.940.930.90.870.860.860.850.850.850.840.840.830.830.830.820.820.810.810.810.810.810.780.760.750.750.750.750.750.75
CIDR+PGF10.920.730.720.720.70.70.690.690.680.680.680.680.680.680.670.660.660.660.630.610.590.570.540.530.530.530.520.510.50.50.5
Cyclic heifers - Preg
012345678910111213141516171819202122232425262728293031
Control10.960.920.910.890.870.850.820.810.760.730.730.690.660.620.60.570.520.510.480.470.450.440.430.420.40.390.380.370.360.360.36
PGF10.860.820.80.790.790.780.770.770.760.750.750.740.730.70.680.680.640.60.560.540.510.490.480.480.460.450.450.450.440.440.44
CIDR+PGF10.910.580.510.50.50.490.490.490.480.480.480.480.480.480.470.470.470.470.470.460.420.40.380.370.350.340.320.320.320.320.32
Dairy IFS
012345678910111213141516171819202122232425262728293031
PGF10.620.470.430.410.390.380.380.380.370.360.360.350.340.320.310.30.270.220.20.190.170.160.140.130.130.130.130.130.130.110.11
CIDR+PGF10.860.320.160.110.110.110.110.110.10.10.10.10.10.10.10.10.10.10.090.090.070.070.070.070.070.070.070.060.060.060.06
Dairy Preg
012345678910111213141516171819202122232425262728293031
PGF10.750.660.620.610.60.60.590.590.590.590.590.590.580.560.560.550.540.510.50.490.460.460.450.450.430.430.430.430.430.430.43
CIDR+PGF10.940.640.550.530.530.530.530.530.530.530.520.520.520.520.520.520.520.520.50.480.470.450.440.420.420.420.420.410.410.410.41
Sheet3
% Concepcin Primer ServicioVacas Carne
Celo y Preez en Vaq de Carne que se les di Progesterona intravaginal724 Vaq. de carne peripuberales en 5 lugares: Florida, Illinois, Missouri, Montana, and Nebraska.
Tres tratamientos:Control no tradadoPGF (Lutalyse) Tratadas con CIDR por 7 das con PGF al da 6
Porcentage en Celo en das 1 al 7 Vaquillonas Carne
Fig. 1
4.9220.2214.84
5.4611.2452.75
6.014.4910.99
6.565.061.1
4.372.811.1
2.732.810.55
7.12.810.55
Control
PGF
CIDR+PGF
Dias del Periodo de Servicio
Porcentage en Celo
Fig. 2A
111
0.980.880.94
0.950.840.59
0.890.810.55
0.870.770.5
0.830.710.47
0.80.640.46
0.740.60.46
0.720.60.46
0.660.580.46
0.620.560.46
0.590.550.46
0.570.510.46
0.510.50.46
0.50.450.46
0.480.440.46
0.440.440.46
0.440.40.46
0.430.40.46
0.40.390.46
0.390.390.45
0.390.380.44
0.380.380.39
0.380.370.36
0.380.360.36
0.370.360.36
0.370.360.36
0.360.360.35
0.360.340.35
0.360.340.35
0.340.340.35
0.330.320.34
A
2a
2a
Control
PGF
CIDR+PGF
Proportion of Cows Not Observed in Estrus
Anestrous Cows
Fig. 2B
111
0.930.810.85
0.870.60.38
0.810.510.28
0.80.470.22
0.770.470.19
0.750.460.18
0.720.440.18
0.70.430.18
0.660.430.18
0.630.430.18
0.60.40.18
0.570.390.18
0.540.390.18
0.490.390.18
0.470.390.18
0.430.340.18
0.380.290.18
0.360.280.18
0.330.260.18
0.290.220.18
0.280.210.16
0.270.180.14
0.260.170.13
0.250.170.11
0.240.170.1
0.240.140.09
0.240.120.09
0.240.120.09
0.220.120.09
0.20.120.09
0.180.120.09
B
Control
PGF
CIDR+PGF
Day of Breeding Period
Proportion of Cows Not Observed in Estrus
Cyclic Cows
Fig. 3A
111
0.990.920.96
0.970.910.76
0.960.910.74
0.960.880.71
0.920.850.69
0.90.80.69
0.850.770.69
0.840.760.69
0.790.750.69
0.770.730.69
0.750.720.69
0.740.70.69
0.70.690.69
0.70.660.69
0.680.660.69
0.680.660.69
0.670.640.69
0.660.640.69
0.640.630.69
0.640.630.69
0.640.630.66
0.640.610.62
0.640.610.56
0.620.60.56
0.610.590.56
0.610.590.55
0.610.590.54
0.610.560.54
0.610.550.54
0.590.550.54
0.580.530.54
A
2a
2a
Control
PGF
CIDR+PGF
Proportion of Cows Not Pregnant
Anestrous Cows
Fig. 3B
111
0.950.860.92
0.920.720.6
0.890.660.54
0.880.630.49
0.880.630.48
0.860.630.48
0.840.610.48
0.830.610.48
0.80.60.48
0.780.60.48
0.760.590.47
0.740.590.47
0.730.590.47
0.690.590.47
0.690.590.47
0.660.550.47
0.610.510.47
0.60.50.47
0.580.490.47
0.580.470.47
0.550.460.45
0.540.430.43
0.520.40.4
0.50.390.36
0.480.390.32
0.480.370.3
0.480.350.3
0.450.350.29
0.440.350.29
0.440.350.29
0.420.350.29
B
Control
PGF
CIDR+PGF
Day of Breeding Period
Proportion of Cows Not Pregnant
Cyclic Cows
Fig. 4
4.9220.2214.84
5.4611.2452.75
6.014.4910.99
6.565.061.1
4.372.811.1
2.732.810.55
7.12.810.55
2a
2a
Control
PGF
CIDR+PGF
Day of Breeding Period
Percentage in Estrus
Fig. 5A
111
0.990.930.91
0.970.890.58
0.930.890.52
0.880.870.51
0.860.830.5
0.860.790.5
0.790.770.49
0.780.760.49
0.740.750.49
0.730.740.48
0.690.740.48
0.680.730.48
0.670.730.48
0.660.720.47
0.650.720.46
0.640.710.45
0.640.670.44
0.610.650.42
0.610.650.38
0.590.620.35
0.550.620.34
0.530.620.34
0.510.620.31
0.50.60.3
0.50.590.3
0.50.590.3
0.50.590.3
0.490.590.29
0.470.560.29
0.470.550.29
0.460.550.29
A
2a
2a
Control
PGF
CIDR+PGF
Proportion of Heifers Not Observed in Estrus
Prepubertal Heifers
Fig. 5B
111
0.920.790.84
0.870.680.32
0.830.630.2
0.780.580.19
0.740.580.19
0.70.570.18
0.660.550.18
0.650.540.18
0.560.540.17
0.520.540.17
0.50.540.17
0.450.520.17
0.420.480.17
0.40.410.17
0.370.390.17
0.320.350.17
0.280.30.16
0.240.240.16
0.220.210.16
0.190.190.16
0.180.180.11
0.170.170.1
0.170.150.09
0.170.150.09
0.160.140.09
0.150.140.09
0.150.130.08
0.140.130.08
0.130.120.08
0.130.120.08
0.130.120.08
B
Control
PGF
CIDR+PGF
Day of Breeding Period
Proportion of Heifers Not Observed in Estrus
Cyclic Heifers
Fig. 6A
111
10.940.92
0.980.940.73
0.940.940.72
0.940.930.72
0.910.90.7
0.910.870.7
0.880.860.69
0.880.860.69
0.850.850.68
0.850.850.68
0.820.850.68
0.820.840.68
0.810.840.68
0.80.830.68
0.790.830.67
0.790.830.66
0.790.820.66
0.780.820.66
0.780.810.63
0.770.810.61
0.730.810.59
0.720.810.57
0.720.810.54
0.720.780.53
0.720.760.53
0.720.750.53
0.720.750.52
0.710.750.51
0.690.750.5
0.690.750.5
0.690.750.5
A
2a
2a
Control
PGF
CIDR+PGF
Proportion of Heifers Not Pregnant
Prepubertal Heifers
Fig. 6B
111
0.960.860.91
0.920.820.58
0.910.80.51
0.890.790.5
0.870.790.5
0.850.780.49
0.820.770.49
0.810.770.49
0.760.760.48
0.730.750.48
0.730.750.48
0.690.740.48
0.660.730.48
0.620.70.48
0.60.680.47
0.570.680.47
0.520.640.47
0.510.60.47
0.480.560.47
0.470.540.46
0.450.510.42
0.440.490.4
0.430.480.38
0.420.480.37
0.40.460.35
0.390.450.34
0.380.450.32
0.370.450.32
0.360.440.32
0.360.440.32
0.360.440.32
B
Control
PGF
CIDR+PGF
Day of Breeding Period
Proportion of Heifers Not Pregnant
Cyclic Heifers
Fig. 7
43.0914.78
16.2657.39
4.8817.39
2.444.35
1.630
0.810
0.810
2a
2a
PGF
CIDR+PGF
Day of Breeding Period
Percentage in Estrus
Fig. 8A
11
0.620.86
0.470.32
0.430.16
0.410.11
0.390.11
0.380.11
0.380.11
0.380.11
0.370.1
0.360.1
0.360.1
0.350.1
0.340.1
0.320.1
0.310.1
0.30.1
0.270.1
0.220.1
0.20.09
0.190.09
0.170.07
0.160.07
0.140.07
0.130.07
0.130.07
0.130.07
0.130.07
0.130.06
0.130.06
0.110.06
0.110.06
A
2a
2a
PGF
CIDR+PGF
Proportion of Heifers Not Observed in Estrus
Dairy Heifers
Fig. 8B
11
0.750.94
0.660.64
0.620.55
0.610.53
0.60.53
0.60.53
0.590.53
0.590.53
0.590.53
0.590.53
0.590.52
0.590.52
0.580.52
0.560.52
0.560.52
0.550.52
0.540.52
0.510.52
0.50.5
0.490.48
0.460.47
0.460.45
0.450.44
0.450.42
0.430.42
0.430.42
0.430.42
0.430.41
0.430.41
0.430.41
0.430.41
B
PGF
CIDR+PGF
Day of Breeding Period
Proportion of Heifers Not Pregnant
Dairy Heifers
Int to estrus data
1234567
Control3.816.677.621.95.243.336.19
PGF17.8915.67.84.594.135.963.67
CIDR+PGF1352.028.976.733.591.790
1234567
Control4.925.466.016.564.372.737.1
PGF20.2211.244.495.062.812.812.81
CIDR+PGF14.8452.7510.991.11.10.550.55
1234567
PGF43.0916.264.882.441.630.810.81
CIDR+PGF14.7857.3917.394.35000
Survival Data
Anestrus Cows - IFS
012345678910111213141516171819202122232425262728293031
Control10.980.950.890.870.830.80.740.720.660.620.590.570.510.50.480.440.440.430.40.390.390.380.380.380.370.370.360.360.360.340.33
PGF10.880.840.810.770.710.640.60.60.580.560.550.510.50.450.440.440.40.40.390.390.380.380.370.360.360.360.360.340.340.340.32
CIDR+PGF10.940.590.550.50.470.460.460.460.460.460.460.460.460.460.460.460.460.460.460.450.440.390.360.360.360.360.350.350.350.350.34
Cyclic Cows - IFS
012345678910111213141516171819202122232425262728293031
Control10.930.870.810.80.770.750.720.70.660.630.60.570.540.490.470.430.380.360.330.290.280.270.260.250.240.240.240.240.220.20.18
PGF10.810.60.510.470.470.460.440.430.430.430.40.390.390.390.390.340.290.280.260.220.210.180.170.170.170.140.120.120.120.120.12
CIDR+PGF10.850.380.280.220.190.180.180.180.180.180.180.180.180.180.180.180.180.180.180.180.160.140.130.110.10.090.090.090.090.090.09
Anestrus Cows - Preg
012345678910111213141516171819202122232425262728293031
Control10.990.970.960.960.920.90.850.840.790.770.750.740.70.70.680.680.670.660.640.640.640.640.640.620.610.610.610.610.610.590.58
PGF10.920.910.910.880.850.80.770.760.750.730.720.70.690.660.660.660.640.640.630.630.630.610.610.60.590.590.590.560.550.550.53
CIDR+PGF10.960.760.740.710.690.690.690.690.690.690.690.690.690.690.690.690.690.690.690.690.660.620.560.560.560.550.540.540.540.540.54
Cyclic Cows - Preg
012345678910111213141516171819202122232425262728293031
Control10.950.920.890.880.880.860.840.830.80.780.760.740.730.690.690.660.610.60.580.580.550.540.520.50.480.480.480.450.440.440.42
PGF10.860.720.660.630.630.630.610.610.60.60.590.590.590.590.590.550.510.50.490.470.460.430.40.390.390.370.350.350.350.350.35
CIDR+PGF10.920.60.540.490.480.480.480.480.480.480.470.470.470.470.470.470.470.470.470.470.450.430.40.360.320.30.30.290.290.290.29
Prepubertal heifers - IFS
012345678910111213141516171819202122232425262728293031
Control10.990.970.930.880.860.860.790.780.740.730.690.680.670.660.650.640.640.610.610.590.550.530.510.50.50.50.50.490.470.470.46
PGF10.930.890.890.870.830.790.770.760.750.740.740.730.730.720.720.710.670.650.650.620.620.620.620.60.590.590.590.590.560.550.55
CIDR+PGF10.910.580.520.510.50.50.490.490.490.480.480.480.480.470.460.450.440.420.380.350.340.340.310.30.30.30.30.290.290.290.29
Cyclic heifers - IFS
012345678910111213141516171819202122232425262728293031
Control10.920.870.830.780.740.70.660.650.560.520.50.450.420.40.370.320.280.240.220.190.180.170.170.170.160.150.150.140.130.130.13
PGF10.790.680.630.580.580.570.550.540.540.540.540.520.480.410.390.350.30.240.210.190.180.170.150.150.140.140.130.130.120.120.12
CIDR+PGF10.840.320.20.190.190.180.180.180.170.170.170.170.170.170.170.170.160.160.160.160.110.10.090.090.090.090.080.080.080.080.08
Prepubertal heifers - Preg
012345678910111213141516171819202122232425262728293031
Control110.980.940.940.910.910.880.880.850.850.820.820.810.80.790.790.790.780.780.770.730.720.720.720.720.720.720.710.690.690.69
PGF10.940.940.940.930.90.870.860.860.850.850.850.840.840.830.830.830.820.820.810.810.810.810.810.780.760.750.750.750.750.750.75
CIDR+PGF10.920.730.720.720.70.70.690.690.680.680.680.680.680.680.670.660.660.660.630.610.590.570.540.530.530.530.520.510.50.50.5
Cyclic heifers - Preg
012345678910111213141516171819202122232425262728293031
Control10.960.920.910.890.870.850.820.810.760.730.730.690.660.620.60.570.520.510.480.470.450.440.430.420.40.390.380.370.360.360.36
PGF10.860.820.80.790.790.780.770.770.760.750.750.740.730.70.680.680.640.60.560.540.510.490.480.480.460.450.450.450.440.440.44
CIDR+PGF10.910.580.510.50.50.490.490.490.480.480.480.480.480.480.470.470.470.470.470.460.420.40.380.370.350.340.320.320.320.320.32
Dairy IFS
012345678910111213141516171819202122232425262728293031
PGF10.620.470.430.410.390.380.380.380.370.360.360.350.340.320.310.30.270.220.20.190.170.160.140.130.130.130.130.130.130.110.11
CIDR+PGF10.860.320.160.110.110.110.110.110.10.10.10.10.10.10.10.10.10.10.090.090.070.070.070.070.070.070.070.060.060.060.06
Dairy Preg
012345678910111213141516171819202122232425262728293031
PGF10.750.660.620.610.60.60.590.590.590.590.590.590.580.560.560.550.540.510.50.490.460.460.450.450.430.430.430.430.430.430.43
CIDR+PGF10.940.640.550.530.530.530.530.530.530.530.520.520.520.520.520.520.520.520.50.480.470.450.440.420.420.420.420.410.410.410.41
Sheet3
Intervalo al CeloVaquillonas Prepuberales
Fig. 1
3.8117.8913
6.6715.652.02
7.627.88.97
1.94.596.73
5.244.133.59
3.335.961.79
6.193.670
2a
2a
Control
PGF
CIDR+PGF
Day of Breeding Period
Percentage in Estrus
Fig. 2A
111
0.990.930.91
0.970.890.58
0.930.890.52
0.880.870.51
0.860.830.5
0.860.790.5
0.790.770.49
0.780.760.49
0.740.750.49
0.730.740.48
0.690.740.48
0.680.730.48
0.670.730.48
0.660.720.47
0.650.720.46
0.640.710.45
0.640.670.44
0.610.650.42
0.610.650.38
0.590.620.35
0.550.620.34
0.530.620.34
0.510.620.31
0.50.60.3
0.50.590.3
0.50.590.3
0.50.590.3
0.490.590.29
0.470.560.29
0.470.550.29
0.460.550.29
Control
PGF
CIDR+PGF
Dias del Periodo de Servicio
Proporcion de Vaquillonas No Observadas en Celo
Fig. 2B
111
0.930.810.85
0.870.60.38
0.810.510.28
0.80.470.22
0.770.470.19
0.750.460.18
0.720.440.18
0.70.430.18
0.660.430.18
0.630.430.18
0.60.40.18
0.570.390.18
0.540.390.18
0.490.390.18
0.470.390.18
0.430.340.18
0.380.290.18
0.360.280.18
0.330.260.18
0.290.220.18
0.280.210.16
0.270.180.14
0.260.170.13
0.250.170.11
0.240.170.1
0.240.140.09
0.240.120.09
0.240.120.09
0.220.120.09
0.20.120.09
0.180.120.09
B
Control
PGF
CIDR+PGF
Day of Breeding Period
Proportion of Cows Not Observed in Estrus
Cyclic Cows
Fig. 3A
111
0.990.920.96
0.970.910.76
0.960.910.74
0.960.880.71
0.920.850.69
0.90.80.69
0.850.770.69
0.840.760.69
0.790.750.69
0.770.730.69
0.750.720.69
0.740.70.69
0.70.690.69
0.70.660.69
0.680.660.69
0.680.660.69
0.670.640.69
0.660.640.69
0.640.630.69
0.640.630.69
0.640.630.66
0.640.610.62
0.640.610.56
0.620.60.56
0.610.590.56
0.610.590.55
0.610.590.54
0.610.560.54
0.610.550.54
0.590.550.54
0.580.530.54
A
2a
2a
Control
PGF
CIDR+PGF
Proportion of Cows Not Pregnant
Anestrous Cows
Fig. 3B
111
0.950.860.92
0.920.720.6
0.890.660.54
0.880.630.49
0.880.630.48
0.860.630.48
0.840.610.48
0.830.610.48
0.80.60.48
0.780.60.48
0.760.590.47
0.740.590.47
0.730.590.47
0.690.590.47
0.690.590.47
0.660.550.47
0.610.510.47
0.60.50.47
0.580.490.47
0.580.470.47
0.550.460.45
0.540.430.43
0.520.40.4
0.50.390.36
0.480.390.32
0.480.370.3
0.480.350.3
0.450.350.29
0.440.350.29
0.440.350.29
0.420.350.29
B
Control
PGF
CIDR+PGF
Day of Breeding Period
Proportion of Cows Not Pregnant
Cyclic Cows
Fig. 4
4.9220.2214.84
5.4611.2452.75
6.014.4910.99
6.565.061.1
4.372.811.1
2.732.810.55
7.12.810.55
2a
2a
Control
PGF
CIDR+PGF
Day of Breeding Period
Percentage in Estrus
Fig. 5A
111
0.990.930.91
0.970.890.58
0.930.890.52
0.880.870.51
0.860.830.5
0.860.790.5
0.790.770.49
0.780.760.49
0.740.750.49
0.730.740.48
0.690.740.48
0.680.730.48
0.670.730.48
0.660.720.47
0.650.720.46
0.640.710.45
0.640.670.44
0.610.650.42
0.610.650.38
0.590.620.35
0.550.620.34
0.530.620.34
0.510.620.31
0.50.60.3
0.50.590.3
0.50.590.3
0.50.590.3
0.490.590.29
0.470.560.29
0.470.550.29
0.460.550.29
A
2a
2a
Control
PGF
CIDR+PGF
Proportion of Heifers Not Observed in Estrus
Prepubertal Heifers
Fig. 5B
111
0.920.790.84
0.870.680.32
0.830.630.2
0.780.580.19
0.740.580.19
0.70.570.18
0.660.550.18
0.650.540.18
0.560.540.17
0.520.540.17
0.50.540.17
0.450.520.17
0.420.480.17
0.40.410.17
0.370.390.17
0.320.350.17
0.280.30.16
0.240.240.16
0.220.210.16
0.190.190.16
0.180.180.11
0.170.170.1
0.170.150.09
0.170.150.09
0.160.140.09
0.150.140.09
0.150.130.08
0.140.130.08
0.130.120.08
0.130.120.08
0.130.120.08
B
Control
PGF
CIDR+PGF
Day of Breeding Period
Proportion of Heifers Not Observed in Estrus
Cyclic Heifers
Fig. 6A
111
10.940.92
0.980.940.73
0.940.940.72
0.940.930.72
0.910.90.7
0.910.870.7
0.880.860.69
0.880.860.69
0.850.850.68
0.850.850.68
0.820.850.68
0.820.840.68
0.810.840.68
0.80.830.68
0.790.830.67
0.790.830.66
0.790.820.66
0.780.820.66
0.780.810.63
0.770.810.61
0.730.810.59
0.720.810.57
0.720.810.54
0.720.780.53
0.720.760.53
0.720.750.53
0.720.750.52
0.710.750.51
0.690.750.5
0.690.750.5
0.690.750.5
A
2a
2a
Control
PGF
CIDR+PGF
Proportion of Heifers Not Pregnant
Prepubertal Heifers
Fig. 6B
111
0.960.860.91
0.920.820.58
0.910.80.51
0.890.790.5
0.870.790.5
0.850.780.49
0.820.770.49
0.810.770.49
0.760.760.48
0.730.750.48
0.730.750.48
0.690.740.48
0.660.730.48
0.620.70.48
0.60.680.47
0.570.680.47
0.520.640.47
0.510.60.47
0.480.560.47
0.470.540.46
0.450.510.42
0.440.490.4
0.430.480.38
0.420.480.37
0.40.460.35
0.390.450.34
0.380.450.32
0.370.450.32
0.360.440.32
0.360.440.32
0.360.440.32
B
Control
PGF
CIDR+PGF
Day of Breeding Period
Proportion of Heifers Not Pregnant
Cyclic Heifers
Fig. 7
43.0914.78
16.2657.39
4.8817.39
2.444.35
1.630
0.810
0.810
2a
2a
PGF
CIDR+PGF
Day of Breeding Period
Percentage in Estrus
Fig. 8A
11
0.620.86
0.470.32
0.430.16
0.410.11
0.390.11
0.380.11
0.380.11
0.380.11
0.370.1
0.360.1
0.360.1
0.350.1
0.340.1
0.320.1
0.310.1
0.30.1
0.270.1
0.220.1
0.20.09
0.190.09
0.170.07
0.160.07
0.140.07
0.130.07
0.130.07
0.130.07
0.130.07
0.130.06
0.130.06
0.110.06
0.110.06
A
2a
2a
PGF
CIDR+PGF
Proportion of Heifers Not Observed in Estrus
Dairy Heifers
Fig. 8B
11
0.750.94
0.660.64
0.620.55
0.610.53
0.60.53
0.60.53
0.590.53
0.590.53
0.590.53
0.590.53
0.590.52
0.590.52
0.580.52
0.560.52
0.560.52
0.550.52
0.540.52
0.510.52
0.50.5
0.490.48
0.460.47
0.460.45
0.450.44
0.450.42
0.430.42
0.430.42
0.430.42
0.430.41
0.430.41
0.430.41
0.430.41
B
PGF
CIDR+PGF
Day of Breeding Period
Proportion of Heifers Not Pregnant
Dairy Heifers
Int to estrus data
1234567
Control3.816.677.621.95.243.336.19
PGF17.8915.67.84.594.135.963.67
CIDR+PGF1352.028.976.733.591.790
1234567
Control4.925.466.016.564.372.737.1
PGF20.2211.244.495.062.812.812.81
CIDR+PGF14.8452.7510.991.11.10.550.55
1234567
PGF43.0916.264.882.441.630.810.81
CIDR+PGF14.7857.3917.394.35000
Survival Data
Anestrus Cows - IFS
012345678910111213141516171819202122232425262728293031
Control10.980.950.890.870.830.80.740.720.660.620.590.570.510.50.480.440.440.430.40.390.390.380.380.380.370.370.360.360.360.340.33
PGF10.880.840.810.770.710.640.60.60.580.560.550.510.50.450.440.440.40.40.390.390.380.380.370.360.360.360.360.340.340.340.32
CIDR+PGF10.940.590.550.50.470.460.460.460.460.460.460.460.460.460.460.460.460.460.460.450.440.390.360.360.360.360.350.350.350.350.34
Cyclic Cows - IFS
012345678910111213141516171819202122232425262728293031
Control10.930.870.810.80.770.750.720.70.660.630.60.570.540.490.470.430.380.360.330.290.280.270.260.250.240.240.240.240.220.20.18
PGF10.810.60.510.470.470.460.440.430.430.430.40.390.390.390.390.340.290.280.260.220.210.180.170.170.170.140.120.120.120.120.12
CIDR+PGF10.850.380.280.220.190.180.180.180.180.180.180.180.180.180.180.180.180.180.180.180.160.140.130.110.10.090.090.090.090.090.09
Anestrus Cows - Preg
012345678910111213141516171819202122232425262728293031
Control10.990.970.960.960.920.90.850.840.790.770.750.740.70.70.680.680.670.660.640.640.640.640.640.620.610.610.610.610.610.590.58
PGF10.920.910.910.880.850.80.770.760.750.730.720.70.690.660.660.660.640.640.630.630.630.610.610.60.590.590.590.560.550.550.53
CIDR+PGF10.960.760.740.710.690.690.690.690.690.690.690.690.690.690.690.690.690.690.690.690.660.620.560.560.560.550.540.540.540.540.54
Cyclic Cows - Preg
012345678910111213141516171819202122232425262728293031
Control10.950.920.890.880.880.860.840.830.80.780.760.740.730.690.690.660.610.60.580.580.550.540.520.50.480.480.480.450.440.440.42
PGF10.860.720.660.630.630.630.610.610.60.60.590.590.590.590.590.550.510.50.490.470.460.430.40.390.390.370.350.350.350.350.35
CIDR+PGF10.920.60.540.490.480.480.480.480.480.480.470.470.470.470.470.470.470.470.470.470.450.430.40.360.320.30.30.290.290.290.29
Prepubertal heifers - IFS
012345678910111213141516171819202122232425262728293031
Control10.990.970.930.880.860.860.790.780.740.730.690.680.670.660.650.640.640.610.610.590.550.530.510.50.50.50.50.490.470.470.46
PGF10.930.890.890.870.830.790.770.760.750.740.740.730.730.720.720.710.670.650.650.620.620.620.620.60.590.590.590.590.560.550.55
CIDR+PGF10.910.580.520.510.50.50.490.490.490.480.480.480.480.470.460.450.440.420.380.350.340.340.310.30.30.30.30.290.290.290.29
Cyclic heifers - IFS
012345678910111213141516171819202122232425262728293031
Control10.920.870.830.780.740.70.660.650.560.520.50.450.420.40.370.320.280.240.220.190.180.170.170.170.160.150.150.140.130.130.13
PGF10.790.680.630.580.580.570.550.540.540.540.540.520.480.410.390.350.30.240.210.190.180.170.150.150.140.140.130.130.120.120.12
CIDR+PGF10.840.320.20.190.190.180.180.180.170.170.170.170.170.170.170.170.160.160.160.160.110.10.090.090.090.090.080.080.080.080.08
Prepubertal heifers - Preg
012345678910111213141516171819202122232425262728293031
Control110.980.940.940.910.910.880.880.850.850.820.820.810.80.790.790.790.780.780.770.730.720.720.720.720.720.720.710.690.690.69
PGF10.940.940.940.930.90.870.860.860.850.850.850.840.840.830.830.830.820.820.810.810.810.810.810.780.760.750.750.750.750.750.75
CIDR+PGF10.920.730.720.720.70.70.690.690.680.680.680.680.680.680.670.660.660.660.630.610.590.570.540.530.530.530.520.510.50.50.5
Cyclic heifers - Preg
012345678910111213141516171819202122232425262728293031
Control10.960.920.910.890.870.850.820.810.760.730.730.690.660.620.60.570.520.510.480.470.450.440.430.420.40.390.380.370.360.360.36
PGF10.860.820.80.790.790.780.770.770.760.750.750.740.730.70.680.680.640.60.560.540.510.490.480.480.460.450.450.450.440.440.44
CIDR+PGF10.910.580.510.50.50.490.490.490.480.480.480.480.480.480.470.470.470.470.470.460.420.40.380.370.350.340.320.320.320.320.32
Dairy IFS
012345678910111213141516171819202122232425262728293031
PGF10.620.470.430.410.390.380.380.380.370.360.360.350.340.320.310.30.270.220.20.190.170.160.140.130.130.130.130.130.130.110.11
CIDR+PGF10.860.320.160.110.110.110.110.110.10.10.10.10.10.10.10.10.10.10.090.090.070.070.070.070.070.070.070.060.060.060.06
Dairy Preg
012345678910111213141516171819202122232425262728293031
PGF10.750.660.620.610.60.60.590.590.590.590.590.590.580.560.560.550.540.510.50.490.460.460.450.450.430.430.430.430.430.430.43
CIDR+PGF10.940.640.550.530.530.530.530.530.530.530.520.520.520.520.520.520.520.520.50.480.470.450.440.420.420.420.420.410.410.410.41
Sheet3
Intervalo al CeloVaquillonas Cclicas
Fig. 1
3.8117.8913
6.6715.652.02
7.627.88.97
1.94.596.73
5.244.133.59
3.335.961.79
6.193.670
2a
2a
Control
PGF
CIDR+PGF
Day of Breeding Period
Percentage in Estrus
Fig. 2A
111
0.920.790.84
0.870.680.32
0.830.630.2
0.780.580.19
0.740.580.19
0.70.570.18
0.660.550.18
0.650.540.18
0.560.540.17
0.520.540.17
0.50.540.17
0.450.520.17
0.420.480.17
0.40.410.17
0.370.390.17
0.320.350.17
0.280.30.16
0.240.240.16
0.220.210.16
0.190.190.16
0.180.180.11
0.170.170.1
0.170.150.09
0.170.150.09
0.160.140.09
0.150.140.09
0.150.130.08
0.140.130.08
0.130.120.08
0.130.120.08
0.130.120.08
Control
PGF
CIDR+PGF
Dias del Periodo de Servicio
Proporcion de VaquillonasNo Observadas en Celo
Fig. 2B
111
0.930.810.85
0.870.60.38
0.810.510.28
0.80.470.22
0.770.470.19
0.750.460.18
0.720.440.18
0.70.430.18
0.660.430.18
0.630.430.18
0.60.40.18
0.570.390.18
0.540.390.18
0.490.390.18
0.470.390.18
0.430.340.18
0.380.290.18
0.360.280.18
0.330.260.18
0.290.220.18
0.280.210.16
0.270.180.14
0.260.170.13
0.250.170.11
0.240.170.1
0.240.140.09
0.240.120.09
0.240.120.09
0.220.120.09
0.20.120.09
0.180.120.09
B
Control
PGF
CIDR+PGF
Day of Breeding Period
Proportion of Cows Not Observed in Estrus
Cyclic Cows
Fig. 3A
111
0.990.920.96
0.970.910.76
0.960.910.74
0.960.880.71
0.920.850.69
0.90.80.69
0.850.770.69
0.840.760.69
0.790.750.69
0.770.730.69
0.750.720.69
0.740.70.69
0.70.690.69
0.70.660.69
0.680.660.69
0.680.660.69
0.670.640.69
0.660.640.69
0.640.630.69
0.640.630.69
0.640.630.66
0.640.610.62
0.640.610.56
0.620.60.56
0.610.590.56
0.610.590.55
0.610.590.54
0.610.560.54
0.610.550.54
0.590.550.54
0.580.530.54
A
2a
2a
Control
PGF
CIDR+PGF
Proportion of Cows Not Pregnant
Anestrous Cows
Fig. 3B
111
0.950.860.92
0.920.720.6
0.890.660.54
0.880.630.49
0.880.630.48
0.860.630.48
0.840.610.48
0.830.610.48
0.80.60.48
0.780.60.48
0.760.590.47
0.740.590.47
0.730.590.47
0.690.590.47
0.690.590.47
0.660.550.47
0.610.510.47
0.60.50.47
0.580.490.47
0.580.470.47
0.550.460.45
0.540.430.43
0.520.40.4
0.50.390.36
0.480.390.32
0.480.370.3
0.480.350.3
0.450.350.29
0.440.350.29
0.440.350.29
0.420.350.29
B
Control
PGF
CIDR+PGF
Day of Breeding Period
Proportion of Cows Not Pregnant
Cyclic Cows
Fig. 4
4.9220.2214.84
5.4611.2452.75
6.014.4910.99
6.565.061.1
4.372.811.1
2.732.810.55
7.12.810.55
2a
2a
Control
PGF
CIDR+PGF
Day of Breeding Period
Percentage in Estrus
Fig. 5A
111
0.990.930.91
0.970.890.58
0.930.890.52
0.880.870.51
0.860.830.5
0.860.790.5
0.790.770.49
0.780.760.49
0.740.750.49
0.730.740.48
0.690.740.48
0.680.730.48
0.670.730.48
0.660.720.47
0.650.720.46
0.640.710.45
0.640.670.44
0.610.650.42
0.610.650.38
0.590.620.35
0.550.620.34
0.530.620.34
0.510.620.31
0.50.60.3
0.50.590.3
0.50.590.3
0.50.590.3
0.490.590.29
0.470.560.29
0.470.550.29
0.460.550.29
A
2a
2a
Control
PGF
CIDR+PGF
Proportion of Heifers Not Observed in Estrus
Prepubertal Heifers
Fig. 5B
111
0.920.790.84
0.870.680.32
0.830.630.2
0.780.580.19
0.740.580.19
0.70.570.18
0.660.550.18
0.650.540.18
0.560.540.17
0.520.540.17
0.50.540.17
0.450.520.17
0.420.480.17
0.40.410.17
0.370.390.17
0.320.350.17
0.280.30.16
0.240.240.16
0.220.210.16
0.190.190.16
0.180.180.11
0.170.170.1
0.170.150.09
0.170.150.09
0.160.140.09
0.150.140.09
0.150.130.08
0.140.130.08
0.130.120.08
0.130.120.08
0.130.120.08
B
Control
PGF
CIDR+PGF
Day of Breeding Period
Proportion of Heifers Not Observed in Estrus
Cyclic Heifers
Fig. 6A
111
10.940.92
0.980.940.73
0.940.940.72
0.940.930.72
0.910.90.7
0.910.870.7
0.880.860.69
0.880.860.69
0.850.850.68
0.850.850.68
0.820.850.68
0.820.840.68
0.810.840.68
0.80.830.68
0.790.830.67
0.790.830.66
0.790.820.66
0.780.820.66
0.780.810.63
0.770.810.61
0.730.810.59
0.720.810.57
0.720.810.54
0.720.780.53
0.720.760.53
0.720.750.53
0.720.750.52
0.710.750.51
0.690.750.5
0.690.750.5
0.690.750.5
A
2a
2a
Control
PGF
CIDR+PGF
Proportion of Heifers Not Pregnant
Prepubertal Heifers
Fig. 6B
111
0.960.860.91
0.920.820.58
0.910.80.51
0.890.790.5
0.870.790.5
0.850.780.49
0.820.770.49
0.810.770.49
0.760.760.48
0.730.750.48
0.730.750.48
0.690.740.48
0.660.730.48
0.620.70.48
0.60.680.47
0.570.680.47
0.520.640.47
0.510.60.47
0.480.560.47
0.470.540.46
0.450.510.42
0.440.490.4
0.430.480.38
0.420.480.37
0.40.460.35
0.390.450.34
0.380.450.32
0.370.450.32
0.360.440.32
0.360.440.32
0.360.440.32
B
Control
PGF
CIDR+PGF
Day of Breeding Period
Proportion of Heifers Not Pregnant
Cyclic Heifers
Fig. 7
43.0914.78
16.2657.39
4.8817.39
2.444.35
1.630
0.810
0.810
2a
2a
PGF
CIDR+PGF
Day of Breeding Period
Percentage in Estrus
Fig. 8A
11
0.620.86
0.470.32
0.430.16
0.410.11
0.390.11
0.380.11
0.380.11
0.380.11
0.370.1
0.360.1
0.360.1
0.350.1
0.340.1
0.320.1
0.310.1
0.30.1
0.270.1
0.220.1
0.20.09
0.190.09
0.170.07
0.160.07
0.140.07
0.130.07
0.130.07
0.130.07
0.130.07
0.130.06
0.130.06
0.110.06
0.110.06
A
2a
2a
PGF
CIDR+PGF
Proportion of Heifers Not Observed in Estrus
Dairy Heifers
Fig. 8B
11
0.750.94
0.660.64
0.620.55
0.610.53
0.60.53
0.60.53
0.590.53
0.590.53
0.590.53
0.590.53
0.590.52
0.590.52
0.580.52
0.560.52
0.560.52
0.550.52
0.540.52
0.510.52
0.50.5
0.490.48
0.460.47
0.460.45
0.450.44
0.450.42
0.430.42
0.430.42
0.430.42
0.430.41
0.430.41
0.430.41
0.430.41
B
PGF
CIDR+PGF
Day of Breeding Period
Proportion of Heifers Not Pregnant
Dairy Heifers
Int to estrus data
1234567
Control3.816.677.621.95.243.336.19
PGF17.8915.67.84.594.135.963.67
CIDR+PGF1352.028.976.733.591.790
1234567
Control4.925.466.016.564.372.737.1
PGF20.2211.244.495.062.812.812.81
CIDR+PGF14.8452.7510.991.11.10.550.55
1234567
PGF43.0916.264.882.441.630.810.81
CIDR+PGF14.7857.3917.394.35000
Survival Data
Anestrus Cows - IFS
012345678910111213141516171819202122232425262728293031
Control10.980.950.890.870.830.80.740.720.660.620.590.570.510.50.480.440.440.430.40.390.390.380.380.380.370.370.360.360.360.340.33
PGF10.880.840.810.770.710.640.60.60.580.560.550.510.50.450.440.440.40.40.390.390.380.380.370.360.360.360.360.340.340.340.32
CIDR+PGF10.940.590.550.50.470.460.460.460.460.460.460.460.460.460.460.460.460.460.460.450.440.390.360.360.360.360.350.350.350.350.34
Cyclic Cows - IFS
012345678910111213141516171819202122232425262728293031
Control10.930.870.810.80.770.750.720.70.660.630.60.570.540.490.470.430.380.360.330.290.280.270.260.250.240.240.240.240.220.20.18
PGF10.810.60.510.470.470.460.440.430.430.430.40.390.390.390.390.340.290.280.260.220.210.180.170.170.170.140.120.120.120.120.12
CIDR+PGF10.850.380.280.220.190.180.180.180.180.180.180.180.180.180.180.180.180.180.180.180.160.140.130.110.10.090.090.090.090.090.09
Anestrus Cows - Preg
012345678910111213141516171819202122232425262728293031
Control10.990.970.960.960.920.90.850.840.790.770.750.740.70.70.680.680.670.660.640.640.640.640.640.620.610.610.610.610.610.590.58
PGF10.920.910.910.880.850.80.770.760.750.730.720.70.690.660.660.660.640.640.630.630.630.610.610.60.590.590.590.560.550.550.53
CIDR+PGF10.960.760.740.710.690.690.690.690.690.690.690.690.690.690.690.690.690.690.690.690.660.620.560.560.560.550.540.540.540.540.54
Cyclic Cows - Preg
012345678910111213141516171819202122232425262728293031
Control10.950.920.890.880.880.860.840.830.80.780.760.740.730.690.690.660.610.60.580.580.550.540.520.50.480.480.480.450.440.440.42
PGF10.860.720.660.630.630.630.610.610.60.60.590.590.590.590.590.550.510.50.490.470.460.430.40.390.390.370.350.350.350.350.35
CIDR+PGF10.920.60.540.490.480.480.480.480.480.480.470.470.470.470.470.470.470.470.470.470.450.430.40.360.320.30.30.290.290.290.29
Prepubertal heifers - IFS
012345678910111213141516171819202122232425262728293031
Control10.990.970.930.880.860.860.790.780.740.730.690.680.670.660.650.640.640.610.610.590.550.530.510.50.50.50.50.490.470.470.46
PGF10.930.890.890.870.830.790.770.760.750.740.740.730.730.720.720.710.670.650.650.620.620.620.620.60.590.590.590.590.560.550.55
CIDR+PGF10.910.580.520.510.50.50.490.490.490.480.480.480.480.470.460.450.440.420.380.350.340.340.310.30.30.30.30.290.290.290.29
Cyclic heifers - IFS
012345678910111213141516171819202122232425262728293031
Control10.920.870.830.780.740.70.660.650.560.520.50.450.420.40.370.320.280.240.220.190.180.170.170.170.160.150.150.140.130.130.13
PGF10.790.680.630.580.580.570.550.540.540.540.540.520.480.410.390.350.30.240.210.190.180.170.150.150.140.140.130.130.120.120.12
CIDR+PGF10.840.320.20.190.190.180.180.180.170.170.170.170.170.170.170.170.160.160.160.160.110.10.090.090.090.090.080.080.080.080.08
Prepubertal heifers - Preg
012345678910111213141516171819202122232425262728293031
Control110.980.940.940.910.910.880.880.850.850.820.820.810.80.790.790.790.780.780.770.730.720.720.720.720.720.720.710.690.690.69
PGF10.940.940.940.930.90.870.860.860.850.850.850.840.840.830.830.830.820.820.810.810.810.810.810.780.760.750.750.750.750.750.75
CIDR+PGF10.920.730.720.720.70.70.690.690.680.680.680.680.680.680.670.660.660.660.630.610.590.570.540.530.530.530.520.510.50.50.5
Cyclic heifers - Preg
012345678910111213141516171819202122232425262728293031
Control10.960.920.910.890.870.850.820.810.760.730.730.690.660.620.60.570.520.510.480.470.450.440.430.420.40.390.380.370.360.360.36
PGF10.860.820.80.790.790.780.770.770.760.750.750.740.730.70.680.680.640.60.560.540.510.490.480.480.460.450.450.450.440.440.44
CIDR+PGF10.910.580.510.50.50.490.490.490.480.480.480.480.480.480.470.470.470.470.470.460.420.40.380.370.350.340.320.320.320.320.32
Dairy IFS
012345678910111213141516171819202122232425262728293031
PGF10.620.470.430.410.390.380.380.380.370.360.360.350.340.320.310.30.270.220.20.190.170.160.140.130.130.130.130.130.130.110.11
CIDR+PGF10.860.320.160.110.110.110.110.110.10.10.10.10.10.10.10.10.10.10.090.090.070.070.070.070.070.070.070.060.060.060.06
Dairy Preg
012345678910111213141516171819202122232425262728293031
PGF10.750.660.620.610.60.60.590.590.590.590.590.590.580.560.560.550.540.510.50.490.460.460.450.450.430.430.430.430.430.430.43
CIDR+PGF10.940.640.550.530.530.530.530.530.530.530.520.520.520.520.520.520.520.520.50.480.470.450.440.420.420.420.420.410.410.410.41
Sheet3
% Concepcin Primer ServicioVaquillonas Carne
Anestros mayores de 60 dasRodeo Waseca (Universidad de Minnesota)
Bajo Nivel secrecinde LH / FSH Folculos grandesAlta produccinestrgenosPico LHyovulacinNo acumulacinde LH / FSHPermanece en anestroProgesteronamantiene bajosniveles desecrecinde LH / FSH Acumulacinde LH / FSHNivel alto secrecinde LH / FSHCeloAnestroAnestro+ CIDRFolculos pequeosBaja produccinestrgenosNo picoLH Retiro de CIDR
Anestro PospartoTratamientos hormonalesGnRH
eCG
Estradiol
Progesterona / Progestgenos
Tratamientos hormonalesPROGESTERONA SOLA
No siempre estimula el reinicio de actividad cclica.No reduce el intervalo a la ovulacin.SI intervalos entre ovulaciones con normal funcin luteal y tamao de CL
Beneficio: inicia ciclos estrales de duracin normal
Tratamientos hormonalesPROGESTERONA + eCG
Estimular el desarrollo de folculos ovricos y la produccin de estradiolNo fue consistente en aumentar la performance reproductiva
Tratamientos hormonalesPROGESTERONA + BE
Estimular ovulacin y expresin del celo
Respuesta al celo, ovulacin y preez en vacas lecheras en AnestroCIDR - P4 + BECelo = 87% 7d (69/100)1ra IA = 42% (27/62) Rhodes y col., 1998
87% = ovul. 79% (54/95%) Rhodes y col., 2001CIDR - P4
39% ovul 30 dpp Gorgerino, 200740% ovul 50 dpp Wiltbank, 2007
Respuesta al celo y preez en vacas lecheras en AnestroCIDR + BE Vacas LecheCelo = 89.6% 14 d. - 68.4% 4 d.1ra IA = 49.5%Preez = 75.7% (2 IA) - 66.9% total animalesAlem y Dick, 1994
CIDR + BE Vacas LecheCelo = 77.7% 7 d.1ra IA = 35.7%Preez (2 IA) = 78.5%Gasilln y Dick, 1999
Respuesta en preez al momento posparto en vacas lecheras en anestroCIDR + BE Vacas Leche
Tratamiento 38 - 55 dpp1ra IA = 43.5%Preez = 56.5% en 2 IA
Tratamiento 56 - 105 dpp1ra IA = 42.7%Preez = 69.9% en 2 IADick, 1996
Tratamiento temprano v. tarde de CIDRHanlon, Wichtel, Xu & Burton, (2000)
Tem:
FIS -8
Tarde:
FIS +1-6
Sig
P=
% Insem a D21
95.0%
63.1%
0.001
1ra IA
48.9%
59.8%
0.01
Preez a D 21
59.5%
38.8%
0.001
No preadas
7.7%
6.0%
NS
FIS a concepcin
19.7 das
27.2
das
0.001
Resultado: Meta-analisis de ensayo de campo(Rabiee, Lean and Stevenson, 2004)CIDRs en vacas lecheras en anestro (Riesgo Relativo de preez)
1er servicio %: 0.91 (0.68-1.26) x (7 ensayos)controles
% Total preez: 0.97 (0.59-1.60) x (3 ensayos)controles
Vacas en Anestro(%) de vacas McDougall, 2004
% Inseminacin en vacas lecheras en anestroMcDougall, 2004
ndice acumulado de preez Vacas en anestro (AA)
Tratamiento y % de concepcin al 1er servicio en vacas en anestroMcDougall y col. no publicadoNS
% Inseminacin y C.C.
Edad y concepcin al 1er servicio en vacas en anestroMcDougall 2003 NZVJ 51:117-124
Sincronizacin con CIDR en Vacas LecherasRyan y col. ( 2000)
Sincronizacin con CIDR en Vacas LecherasXu y col. (2000)
Sncronizacin de la Onda Folicular y la Ovulation
Protocolo de IATF con CIDR
% Preez en Vacas Lecheras Protocolo Ovsynch + P4Veneranda y col., 2006CIDRGnRH PGF2 GnRH IATF (60h)D 0 D7 D9 D10
NDELLecheLactC. C.Pr%Preez9813825.83.143.084242.889711625.12.152.94344.32
% Preez en Vacas Lecheras Ovsynch- P4 + Retorno d 18-23 Celo Detectado
Veneranda y col., 2006Da 0 Da 7 Da 9 Da 10 Das 38-43GnRH PGF GnRH IATF IACDCIDR
NPreadas IATF%IACD% DCPreadasCD% TotalPreadas%Acum.90730433.536560.512634.543047.4
Presynch-OvsynchPorcentages Preez (Vacas Lecheras)Moreira y col. 2004 (ASAS/ADSA/PSA)37%43%N = 821 Presynch-Ovsynch; N = 817 Presynch-Ovsynch-CIDR; P < 0.05
Presynch-OvsynchPorcentage Preez (Vacas Lecheras)Moreira y col. 2004 (ASAS/ADSA/PSA)304preadas47 vacas preadas adicionales351preadas
Pre-servicio y presynch IATFCIDRIA al celoIA al celoIA al celoIA al celoVacas en anestro
Pre-servicio y presynch IATFMelendez y col. (2006) JDS 89:4567-4572CIDRIA al celoIA al celoPR = 22.7%N = 589 vacasPR = 31.2%N = 586 vacas
Segunda InseminacinResincroIATF - IACD
RE-SINCRONIZACIN:EL ENFOQUE DE LA RE-SINCRONIZACIN ES PARA:
AUMENTAR % DE INSEMINACIN, ENTRE VACAS QUE NO CONCIBEN A LA 1RA IA y MEJORAR LA DETECCIN DE CELOS
SIMPLIFICA TIEMPOS DE DE INSEMINACION
PERMITE RE-TRATAMIENTO DE LAS VACAS EN ANESTRO
PERMITE UN TEMPRANO DIAGNSTICO DE PREEZ EN ANIMALES NO RETORNADOS A LA 1RA IA
EL XITO DE LA RE-SINCRONIZACIN SE REFLEJA POR SIMILARES % DE NO RETORNO y SU CONCEPCIN
RE-SINCRONIZACIN:
LA PROGESTERONA NO ESTIMULA MUCHO LOS ANIMALES NO CCLICOS PERO CONCENTRA EL RETORNO AL SERVICIO
El ESTRADIOL SE USA PARA ESTIMULAR (TRATAR) LAS VACAS EN ANESTRO
SINCRONIZACIN DEL RETORNODA +18: INSERTAR CIDR Da 18 Ciclo Estral, Celo = 0
DA +23: EXTRAER CIDR Da 23 Ciclo Estral
DA +24: INSEMINACIN AL CELO DETECTADO
DA +25: INSEMINACIN AL CELO DETECTADO
DA +26: INSEMINACIN AL CELO DETECTADO
SINCRONIZACIN DEL RETORNODA +13: INSERTAR CIDR + BE Da 13 Celo = 0
DA +21: EXTRAER CIDR Da 21DA +22: INYECTAR BE
DA +23: INSEMINACIN AL CELO DETECTADO
DA +24: INSEMINACIN AL CELO DETECTADO
DA +25: INSEMINACIN AL CELO DETECTADO
SINCRONIZACIN DEL RETORNO AL SERVICIO CON O SIN BE DESPUS DEL RETIRO DEL CIDR
DAS DE 2DA INSEM
BE -
BE +
DA 23
44%
71%
DA 24
42%
23%
DA 2