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CURRICULUM VITAE

Name: Wanninayake Mudiyanselage Tilakaratne Marital Status: Married

Home address: 132/9 Upper Augustawatta, Uda-Peradeniya, Kandy, Sri Lanka Undergraduate career: First in the batch at the Final BDS examination Present appointment: Dean and Chair Professor of Oral Pathology Faculty of Dental Sciences University of Peradeniya Sri Lanka President: International Association of Oral- - Pathologists: 2016-18 Email - wmtilak@pdn.ac.lk TP - 94 8 2397201 Fax - 94 8 388948

Previous and other Present Appointments:

Adjunct Visiting Professor at Manipal College of Dental Sciences, Manipal University, India, 2016-18

Founder Director, Centre for Research in Oral Cancer, Faculty of Dental Sciences, University of Peradeniya, Sri Lanka 2013-2015

Visiting Professor, Faculty of Dentistry, University of Malaya, Malaysia, 2015/16

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“Sir Thomas Key Sidey visiting Professor” Faculty of Dentistry, University of Otago, New Zealand, 2013.

Professor of Oral Pathology, School of Medicine and Dentistry, Barts and the London, Queen Mary,University of London, UK 2010-11

Professional Fellow to Queen Mary University of London, UK, 2007-2012 Councillor for Asia at the International Association of Oral Pathologists,

2008-2012. Senior Lecturer (Clinical) in Oral Pathology, School of Medicine and

Dentistry Barts and the London Queen Mary, University of London United Kingdom, 2005-07.

Visiting Professor to University of Niigata, Japan, 2005 Lecturer in Oral Pathology and Radiology, Guy's Hospital, London, UK

1996-1999 Lecturer and in Oral Pathology, University of Birmingham, UK, 1999 Proctor, University of Peradeniya, Sri Lanka 2007-2008 Head Department of Oral Pathology, Faculty of Dental Sciences, University of

Peradeniya, Sri Lanka

Qualifications: BDS (SL) MS (Col) PhD (JP) FDSRCS (UK) FRCPath (UK) University Education: University of Peradeniya, Sri Lanka

Professional experience:

Working as a consultant Oral Pathologist for more than 25 years involving a very busy diagnostic service

Teacher in Oral and General Pathology for both undergraduates and postgraduates for 25 years in different countries

Examiner in both undergraduates and postgraduates examinations locally and internationally for more than 25 years

Memberships:

Fellow of the National Academy of Sciences from 2017 Member of the Working Committee on Health Sciences at National Science

Foundation, 2016-19 Chairman of the smokeless tobacco sub-committee in the National Authority

on Tobacco and Alcohol (NATA), Sri Lanka 2015. Member of the Professional conduct committee of the Sri Lanka Medical

Council of Sri Lanka, 2015 to date.

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Member of the Preliminary proceedings committee of Sri Lanka Medical Council, 2015 to date.

International Association of Oral Pathologists (President Elect): 2014-16 Board member of Sri Lanka Medical Council: 2015- to date Member of the Board of Management of Postgraduate Institute of Medicine

Sri Lanka: 2015- to date Member of the Standing Committee for Medicine and Dentistry, University

Grants Commission of Sri Lanka Member of the Council of University of Peradeniya 2014- to date British Society of Oral and Maxillo-facial Pathology College of Pathologists of Sri Lanka Asian Society of Oral Pathologists (Founder committee member) Sri Lanka Dental Association Member of the Committee on undergraduate, postgraduate and continuing

Education. Sri Lanka Society of Allergy and Immunology Member of the Senate, University of Peradeniya: 2000 to date Vice President, Kandy Society of Medicine- 2013 Member of the Board of Study in Dental Surgery (Post-graduate institute of

Medicine Colombo, Sri Lanka) Founder Board member for the Centre for study of Human Rights, University

of Peradeniya, 2003-05 Chairman, Specialty Board in Oral Pathology, Postgraduate Institute of

Medicine Colombo, Sri Lanka:2007 - 2015

Membership in other committees in the University (Present and past):

Board member; International Research Centre, University of Peradeniya 2015 Warden, Senaka Bibile, University of Peradeniya 2001-2004 Chairman- Faculty Higher degrees committee Chairman- Tobacco cessation unit Chairman- computer aided learning unit Chairman- Foreign qualifications committee Chairman- Maintenance committee Chairman - Research in Molecular Biology University sports advisory committee Faculty research and ethical Review committee Faculty corporate plans committee Academic development and planning Committee Faculty co-group committee Faculty clinical audit committee Curriculum reforms committee Equipment procurement committee Review of University reforms and synchronization of academic

programme committee

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Scholarships committee Staff development committee JICA – 3rd country training programme Committee Member of the governing body of the centre for study of human rights Member of the teaching evaluation committee Member of the treatment evaluation committee

Editorial boards/Advisory panel of Journals:

Journal of Investigative and Clinical Dentistry (Associate Editor) International Journal of Genetics and Genomics Journal of Oral and Maxillofacial Surgery Medicine and Pathology Journal of Oral Surgery Oral Medicine Oral Pathology Oral Radiology and

Endodontology ISRN Pathology Microbial Pathophysiology and Pathogenesis Journal of Orofacial Sciences World Journal of Stomatology Sri Lanka Medical Journal Hantana Vision Manipal Journal of Dental Sciences Indian Journal of Oral and Maxillofacial Pathology

Referee for Journals:

Journal of Oral Pathology and Medicine Oral Diseases Oral Oncology Cancer Investigation Journal of Pathology International Journal of Paediatric Dentistry Journal of Clinica Chimica Acta Archives of Oral Biology Mycopathologia World Journal of Surgical Oncology Cancer Letters Journal of Oral Sugery Oral Medicine Oral Pathology Oral Radiology and

Endodontology Journal of Oral BioSciences Indian Journal of Dental Research Journal of Pathology Research and Practice Journal of Investigative and Clinical Dentistry Journal of Oncology International Journal of Dentistry

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Asian Journal of Oral and Maxillofacial Surgery Journal of Oral Med and Pathology ISRN Pathology Journal of Parasitology Research Journal of the European Academy of Dermatology and Venereology Sri Lanka Medical Journal Sri Lanka Dental Journal Journal of Oral and Maxillofacial Pathology BMC Clinical Pathology European Journal of Molecular Biology Cancer Research Journal Indian Journal of Medical Microbiology Annals of Maxillofacial Surgery Journal of Cellular Biochemistry British Journal of Medicine and Medical Research Tumour Biology Head and Neck Pathology Oral Cancer

Contribution for curriculum development:

1. Development of BDS curriculum: Responsible for the development and reforms of the curriculum in various capacities including chairperson.

2. MD Oral Pathology: The key person in developing and implementing MD Oral Pathology Degree programme of the Postgraduate Institute of Medicine University of Colombo. The first chairman of the Specialty Board in Oral Pathology.

3. Contributed to curricula in MD Oral and Maxillofacial Surgery, Restorative Dentistry, Orthodontics and Dental auxiliary programme.

4. Contributed to the development of MD Forensic Odontology curriculum. Examiner in undergraduate and post graduate examinations (National/International)

1. Examiner for FDSRCS in the Royal College, of Surgeons of England -1998

2. External Examiner Penang International Dental College, Malaysia, 2010 and 2011.

3. External Examiner for University Teknology MARA, Malaysia, 2013.

4. External Examiner for University Teknology MARA, Malaysia, 2013.

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5. External Examiner for Postgraduate Examination in Oral Pathology and Oral

Medicine at University of Malaya, Malaysia.

6. Examiner for BDS examination, University of Peradeniya Sri Lanka.

7. Examiner in Pathology for students at Faculty of Allied Health Sciences, Unversity of Perdeniya, Sri Lanka.

8. Examiner for BDS students at King’s College, London, UK.

9. Examiner for BDS examination at Queen Mary, University of London.

10. Examiner for MSc in Experimental Oral Pathology, Diploma in Clinical Oral Sciences and MSc in Oral Biology at Queen Mary, University of London, UK.

11. Chief Examiner for MD Oral Pathology at PGIM, University of Colombo, Sri Lanka.

12. Examiner for MD Oral and Maxillofacial Surgery at PGIM, University of Colombo, Sri Lanka.

13. Examiner for MD Restorative Dentistry and MD Orthodontics at PGIM, University of Colombo, Sri Lanka.

14. Examiner for Diploma in Hospital Dental Practice and Diploma in General Dental Practice at PGIM, University of Colombo, Sri Lanka.

Research publications Text Books

1. Comprehensive Tumour Terminology. (UICC). Author for three chapters (Wiley –Liss – 2001)

I. Tumours of Salivary Gland II. Tumours of Oral Cavity, pharynx and tongue III. Tumours of the Jaws and teeth

2. Contributor for the Text Book on Clinical Problems solving in Dentistry.

(Chruchill Livingstone – 2001): Award for the second best medical publication in the UK in 2002

3. Chapter on “Oral cavity and Salivary glands” in the second edition of “The

cancer hand book” Two volume book (John Wiley & Sons, Ltd UK) 2007

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4. Text Book of Oral Medicine and Pathology “A Guide to Diagnosis and Treatment” 2013, JAYPEE Medical Publishers, India

5. Contributor for the text book titled “OSCE for Clinical Dental Sciences” 2014, JAYPEE Medical Publishers, India

6. Co-authored a Chapter tilted Oral Submucous Fibrosis in the book “Contemporary Oral Oncology” by Springer 2017.

7. Co-authored 3 chapters in the WHO Blue book on Classification of Head and Neck tumours-2017.

Manuals

1. Manual of special staining Techniques – Workshop for postgraduate trainees in Histopathology 2000

2. Manual of Immunohistochemistry Techniques – Training programme for neighbouring countries 2002.

3. Manual of histological Techniques – Training programme for neighbouring countries 2002

4. Manual on tobacco cessation Methodologies 2004

5. Manual titled “Guideline for the screening, surveillance, diagnosis and management of oral potentially malignant disorders”. Publication of National Cancer control programme of Sri Lanka, 2013.

Publications

1. Heein Yoon, Junhee Park, Kwang-Kyun Park, Jin Kim, N. Champika Bandara, W.

M. Tilakaratne, Won-Yoon Chung. Methanol extract of Holarrhena antidysenterica bark inhibits the growth of human oral squamous cell carcinoma cells and osteoclastogenesis of bone marrow machrophages. Evidence-Based Complementary and Alternative Medicine 2018 (In Press)

2. RMSHB Medawela, DRDL Ratnayake, DRDL Ratnayake, PR Jayasooriya, BSMS Siriwardena, WM Tilakaratne. Malignant transformation of oral lichen planus; the first two cases reported in Sri Lanka and literature review. Sri Lanka Dental Journal;2017;47(01):29-37.

3. Bazarsad S, Zhang X, Kim KY, Illeperuma R, Jayasinghe RD, Tilakaratne WM, Kim J. Identification of a combined biomarker for malignant transformation in oral submucous fibrosis. J Oral Pathol Med (2017) 46: 431-438.

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4. K. Ekanayake, M. Ekanayake and W.M. Tilakaratne. Metastatic paraganglioma presenting in the oral cavity as the initial manifestation. Oral Surgery; 23 NOV 2016, DOI: 10.1111/ors.12235

5. Fernando CN, Abeyratne WMSD, Tilakaratne WM, Siriwardena BSMS. Investigation on the occurrence of Hairy Polyp and Choristoma in Oral Cavity: A case study. Heighpubs Otolaryngol and Rhinol. 2017; 1: 041-045.

6. Jayasuriya NSS, Siriwardena BSMS, Tilakaratne WM, Parthiepan S. Malignant transformation of a long-standing submental dermoid cyst to a carcinosarcoma: a case report. J Med Case Rep. 2017 Jan 11;11(1):11. doi: 10.1186/s13256-016-1186-y.

7. Rosnah Binti Zain, Thomas George Kallarakkal, Anand Ramanathan, Jin Kim, WM Tilakaratne, Takashi Takata, Saman Warnakulasuriya, Vinay Kumar Hazarey, Alison Rich, Haizal Mohd Hussaini, Ajura Jalil. Exophytic Verrucous Hyperplasia of the Oral Cavity – Application of Standardized Criteria for Diagnosis from a Consensus Report. Asian Pac J Cancer Prev 2016;17 (9), 4491-4501

8. RP Ekanayaka,WM Tilakaratne. Oral submucous fibrosis: Review on mechanisms of malignant transformation. Oral Surg, Oral Med, Oral Pathol, Oral Radiol 2016;122 (2),192–199. doi.org/10.1016//j.oooo.2015.12.018

9. LAH Jayasinghe, P.M. Peiris, W.M. Tilakaratne, A.M. Attygalla, R.D. Jayasinghe, M.A.M. Sitheeque, B.S.M.S. Siriwardena. Clinically malignant exophytic lesions in the background of oral submucous fibrosis: report of 5 cases. 2016;122 (2),210–215. DOI: http://dx.doi.org/10.1016/j.oooo.2016.06.001

10. WM Tilakaratne, Rasika Priyadharshani Ekanayaka, Saman Warnakulasuriya Oral submucous fibrosis: A historical perspective and a review on aetiology and pathogenesis. Oral Surg, Oral Med, Oral Pathol, Oral Radiol August 2016;122, (2),178–191. doi.org/10.1016/j.oooo.2016.04.003.

11. PGCL Nanayakkara, WL Dissanayaka, BG Nanayakkara, EAPD Amaratunga, WM Tilakaratne. Comparison of spatula and cytobrush cytological techniques in early detection of oral malignant and premalignant lesions: a prospective and blinded study. 2016 Apr;45(4):268-74. doi: 10.1111/jop.12357

12. RP Ekanayaka, MPB Herath, RD Jayasinghe, MAM Sitheeque, H Amarasinghe, WM Tilakaratne. Intralesional corticosteroids as a treatment for restricted mouth opening in oral submucous fibrosis. Oral Surg, Oral Med, Oral Pathol, Oral Radiol 2016;122, (2) 224–231. doi.org/10.1016/j.oooo.2015.11.023

13. Siriwardena BSMS, Jayathilake DSY, Pitakotuwage TN, Illeperuma RP, Kumarasiri PVR3, Attygalla AM, Peiris HRD, Tilakaratne WM. Demographic and Histopathological Differences of Oral Squamous Cell Carcinoma; Analysis of 4394 Cases from Sri Lanka. J Clin Exp Oncol 2015; 4:4

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14. Siriwardena BSMS, Jayasinghe RD, Tilakaratne WM. Plasma Cell Mucositis Affecting Oral Mucosa: Report of 11 Cases and Review of Literature, J Otol Rhinol 2015, 4:6, http://dx.doi.org/10.4172/2324-8785.1000259

15. Illeperuma RP, Kim DK, Park YJ, Son HK, Kim JY, Kim J, Lee DY, Kim KY,

Jung DW, Tilakaratne WM, Kim J. Areca nut exposure increases secretion of tumor-promoting cytokines in gingival fibroblasts that trigger DNA damage in oral keratinocytes. Int J Cancer. 2015;1;137(11):2545-57. doi: 10.1002/ijc.29636

16. Rajapakshe RMAR, Pallegama RW, Jayasooriya PR, Siriwardena BSMS,

Attygalla AM, Hewapathirana S, Werasinghe JU, Dias DK, Tilakaratne WM. A retrospective analysis to determine factors contributing to the survival of patients with oral squamous cell carcinoma. J of Cancer Epidemiol, 2015 Jun;39(3):360-6.

17. Perera JDR, Sivakanesan R, Jayasinghe RD, Bandara BMR and Tilakaratne WM.

Role of Antioxidants in Disease Progression and Malignant Transformation of Oral Submucous Fibrosis. Sri Lanka Dental Journal, 2014;44 (1-3):15-25.

18. BSMS Siriwardena, S Shunmuganathan, WM Tilakaratne. A case of benign

chondroblastoma in the anterior mandible and review of literature: a very rare presentation. Case Reports in Clinical Medicine, 2015, 4, 102-106.

19. BSMS Siriwardena RMSGK Rasnayaka Yaghma Masood Mohd Masood PVR

Kumarasiri WM Tilakaratne. A Predictive Model of Oral Cancer Metastasis for Different Cancer Sites and Age Groups. Journal of Investigative and Clinical Dentistry (2015), 6, 1–5.

20. BSMS Siriwardena, A. Tilakaratne, WM Tilakaratne A comparative study of oral

squamous cell carcinoma in the young and the old in Sri Lanka. Sri Lanka Dental Journal, 45 (2) 2015, 59-61.

21. RLPR Liyanage, NS Wadusinghearachchi, BSMS Siriwardena, PR Jayasooriya, WM Tilakaratne. Pigmented mucoepidermoid carcinoma with spindle cell differentiation. Oral surgery, oral medicine, oral pathology and oral radiology. 117 (6) e449-e451.2014.

22. Vartoukian SR, Tilakaratne WM, Seoudi N, Bombardieri M, Bergmeier L, Tappuni AR, Fortune F. Dysregulation of the SOCS3-STAT3 pathway in the aetio-pathogenesis of Sjögren's syndrome. Clin Exp Immunol. 2014 Sep;177(3):618-29.

23. Jayasinghe RD, Jayashankar S and Tilakaratne WM. Clinical and Radiological features of Cemento Ossifying Fibromas of the jaws: analysis of 27 cases. Sri Lanka Journal of Medicine 2013: 22 (2); 08-14.

24. Primali Rukmal Jayasooriya, Wanninayaka Mudiyanselage Tilakaratne, Balapuwaduge Ranjit Rigorbert Nihal Mendis, Tommaso Lombardi. A literature review on oral basaloid squamous cell carcinomas, with special emphasis on etiology. Annals of Diagnostic Pathology 2013 Dec;17(6):547-51.

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25. Rasika Priyadharshani Ekanayaka and Wanninayake Mudiyanselage Tilakaratne. Oral submucous fibrosis : Review on mechanisms of pathogenesis and malignant transformation. Journal of Carcinogenesis and Mutagenesis 2013 http://dx.doi.org/4172/2157-2518.S5-002.

26. KSND Gunawardhana , PR Jayasooriya, WM Tilakaratne. Diagnostic dilemma of unicystic ameloblastoma: Novel combination of histopathological features to differentiate unicystic ameloblastoma from common odontogenic cysts. Journal of Investigative and Clinical Dentistry 2013; 4;1–6.

27. RB Zain, Tilakaratne WM et al. A consensus report from the first Asian international regional meeting on the terminology and criteria for verruco-papillary lesions of the oral cavity. ADUM;2013;20 (02);1-3.

28. Siriwardena BSMS, Jayasinghe RD, Ratnatunge N, Tilakaratne WM. Solitary mastocytoma a rare presentation on the buccal mucosa. Case Reports in Clinical Medicine (CRCM) 2013;2(3):174-175.

29. Siriwardena BSMS, Jayasooriya PR, Palitha Ratnayake, Tilakaratne WM. Metastatic tumours of the oral and maxillofacial region: A retrospective analysis of 18 cases. Merit Research Journal of Biochemistry and Bioinformatics (MRJBB) 2013;1(1):1-4.

30. Tilakaratne WM. Oral Cancer and Precancer; Novel markers in malignant transformation and prognosis. Sri Lanka Journal of Medicine 2012;21 (2);12-21.

31. Siriwardena, BSMS, Tennakoon TMPB, Tilakaratne WM. Relative frequency of odontogenic tumours in Sri Lanka: analysis of 1677 cases. Journal of Pathology Practice and Research 2012 Apr 15;208(4):225-30.

32. GN Pitiyage, KP Lim, E Gemenitzidis, MT Teh, A Waseem, SS Prime, WM Tilakaratne F Fortune, EK Parkinson. Increased secretion of tissue inhibitors of metalloproteinases 1 and 2 (TIMPs -1 and -2) in fibroblasts are early indictors of oral sub-mucous fibrosis and ageing. J Oral Pathol Med 2012 Jul;41(6):454-62.

33. NS Wadusinghearachchi, RLPL Liyanage, BSMS Siriwardena, PR Jayasooriya, RMAS Ratnayake, WM Tilakaratne. Primary Squamous cell carcinoma of the parotid gland with prominent intra neural invasion. Sri Lanka Dental Journal 2012;42 (01-02):36-37.

34. Dissanayaka WL, Pitiyage G, Kumarasiri PVR, Liyange RLPR, Dias DK, Tilakaratne WM. Clinical and Histopathological parameters in Survival of oral squamous cell carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol 2012 Apr;113(4):518-25.

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35. Tilakaratne WM, EH Nissanka Jayasooriya. Vaule of HIF-1alpha as an independent prognostic marker in oral squamous cell carcinoma. Expert Rev Mol Diagn (2011);11(2):145-147.

36. Lingen MW, Pinto A, Mendes RA, Franchini R, Czerninski R, Tilakaratne WM, Partridge M, Peterson DE, Woo SB. Genetics/epigenetics of oral premalignancy: current status and future research. Oral Dis. 2011; 17 Suppl 1:7-22.

37. Tilakaratne WM, Morgan PR, Sheriff M, EW Odell. Grading oral epithelial dysplasia: analysis of individual features. J Oral Pathol Med 2011;40(7):533-40.

38. Dissanayake WL, Tilakaratne WM. A histopathologic comparison between synchronous and single primary oral squamous cell carcinomas. In Reply. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011 ;111(1):9-10.

39. Dissanayake R, Jayasooriya PR, Tilakaratne WM. Review on Metastasizing (malignant) Ameloblastoma (METAM): Pattern of Metastasis and treatment. Surg Oral Med Oral Pathol Oral Radiol Endod 2011;111(6):734-41.

40. Mendis BRRN, Lombardi T, Tilakaratne WM. Melanotic neuroectodermal tumour of infancy; histopathological and immunohistochemical study. Journal of Investigative and Clinical Dentistry 2011;2;1-4.

41. KGD Manoja, BSMS Siriwardena, PR Jayasooriya, DJL Siriwardane, WM Tilakaratne. A rare clinical presentation of intra-oral Darier’s disease. Case Reports in Pathology (Hindawi Publishing Corporation) Volume2011, Article ID 181728, 3 pages doi:10.1155/2011/181728.

42. Pitiyage GN, Tilakaratne WM, Parkinson EK et al. "Senescent Mesenchymal Cells Accumulate in Human Fibrosis by a Telomere-Independent Mechanism and Ameliorate Fibrosis through Matrix Metalloproteinases" J of Pathol 2011;223(5):604-17.

43. Jayasooriya PR, Jayasinghe KAN, Tilakaratne WM. Relationship between thickness of fibrosis and epithelial dysplasia in oral submucous fibrosis. Journal of Investigative and Clinical Dentistry (2011), 2, 171–175.

44. Karwan A Moutasim, Veronika Jenei, Karen Sapienza, Daniel Marsh, Paul HWeinreb, Shelia M Violette, Mark P Lewis, John F Marshall, Farida Fortune, Waninayaka Tilakaratne, Ian R Hart & Gareth J Thomas. Alkaloid-dependent integrin upregulation modulates keratinocyte TGF-beta1 activation and promotes oral submucous fibrosis. J Pathol. 2011;223(3):366-77.

45. Rasika Pawiththra Illeperuma, Mi Heon Ryu, Ki Yeol Kim, WM Tilakaratne, Jin Kim. Relationship of fibrosis and the expression of TGF-β1, MMP-1, and TIMP-1 with epithelial dysplasia in oral submucous fibrosis. Oral Med Pathol (2010) 15: 25-32.

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46. Nandasena TL, Jayawardena CK, Tilakaratne WM, Nanayakkara CD. Distribution pattern of cholinesterase enzymes in human tooth germs. Arch Oral Biol. 2010 Aug;55(8):561-9.

47. Mohaideen Sitheeque, Anura Ariyawardana, Ruwan Jayasinghe, Wanninayake Tilakaratne. Depigmentation of oral mucosa as the earliest possible manifestation of oral submucous fibrosis in Sri Lankan preschool children. Journal of Investigative and Clinical Dentistry (2010), 1, 156–159.

48. Gunawardhana KSND, Jayasooriya PR, Rambukewela IK, Tilakaratne WM. A Clinico-pathological comparision between mandibular and maxillary ameloblastomas in Sri Lanka. J Oral Pathol Med. 2010 Mar;39(3):236-41.

49. Dissanayaka WL, Jayasooriya PR, Kumarasiri PV, Tilakaratne WM. A histopathologic comparison between synchronous and single primary oral squamous cell carcinomas. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010 May;109(5):732-8.

50. Dissanayake WL, Jayasooriya PR, Wickramasuriya G, Dias DK, Tilakaratne WM. Oral juvenile xanthogranuloma: report of two cases and review of literature. J Oral Surgery. 2010 (3) 22–25.

51. Siriwardena BSMS, Kudo Y, I Ogawa, Tilakaratne WM, Takata T. Aberrant beta-catenin expression and adenomatous polyposis coli gene mutation in ameloblastoma and odontogenic carcinoma. Oral Oncol. 2009 Feb;45(2):103-8.

52. Pitiyage GN, Tilakaratne WM, Thavasoli M and Warnakulasuriya S. Molecular markers in oral epithelial dysplasia; review". J Oral Pathol Med 2009; 38:737-752.

53. Tilakaratne WM, Jayasuriya PR, Tennkoon TMPB and Saku T. Epithelial salivary gland tumours in Sri Lanka- Retrospective study of 713 cases. Oral Surg Oral Med Oral Pathol Oral Radio Endodontology 2009; 108:90-98

54. Nupehewa D, Jayasooriya PR, Attygalla AM, Tilakaratne WM. Synchronus occurance of oral squamous cell carcinoma and Warthin tumour. Oral Med Pathol 2009; 13:115-117.

55. Jayatilake JA, Tilakaratne WM, Panagoda GJ. Candidal onychomycosis: A Mini-Review. Mycopathologia 2009;108 (4):165-173.

56. Tilakaratne WM, Saku T et al. Matrix metalloproteinase 7 in oral epithelial dysplasia and carcinoma in situ: an aid for histopathologic recognition of their cell proliferation centres. J Oral Pathol Med 2009; 38:348-55.

57. Tilakaratne WM, Teh MT, Pitiyage GN, Ariyawardana A et al. Upregulation of HIF-1alpha in malignant transformation of oral submucous fibrosis. J Oral Pathol Med 2008;37(6):372-7.

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58. Teh MT, Tilakaratne WM et al. Fingerprinting genomic instability in oral submucous fibrosis. J Oral Pathol Med. 2008 Aug;37(7):430-6.

59. Anand Lalli, Wanninayake M Tilakaratne, Caroline Fitchett, Irene M Leigh, Eleni Hagi-Pavli, Alan Cruchley, E. Kenneth Parkinson, Muy-Teck Teh, Farida Fortune and Ahmad Waseem. An altered keratinocyte phenotype in Oral submucous fibrosis: correlation of keratin 17 expression with disease severity. J Oral Pathol Med 2008;37(4):211-20.

60. Siriwardena BSMS, Kudo Y, I Ogawa, Tilakaratne WM, Takata T. VEGF-C is associated with lymphatic status and invasion in Oral cancer. J Clin Pathol. 2008 Jan;61(1):103-8.

61. Tilakaratne WM, Freysdottir J, Fortunre F. Orofacial grnulomatosis; review on aetiology and pathogenesis. J Oral Pathol Med 2008; 37:191-195.

62. Siriwardena BSMS, Tilakaratne WM. Malignant melanoma of the oral mucosa; clinicopathological analysis. Sri Lanka Dental Journal 2008; 38:77-82.

63. Tilakaratne WM, Navaratne G. Microcystic adnexal carcinoma – under diagnosed entity? Sri Lanka Medical Journal 2008;17(2):44-47.

64. Jayasuriya PR, Saku T, Tilakaratne WM. Bcl2 and Bax protein expression in basaloid squamous cell carcinoma of the oral cavity. Sri Lanka Dental Journal Sri lanka Dental Journal 2008;38(01):30-37.

65. Ariyawardana A, MAM Sitheeque, Ranasinghe AW, Perera I, Tilakaratne WM, Amaratunga EAPD, Yi-Hsin Yang, Warnakulasuriya S. Prevalence of oral cancer and precancer and associated risk factors among tea estate workers in the central Sri Lanka. J Oral Pathol Med. 2007 Nov;36(10):581-7.

66. Siriwardena BSMS, Tilakaratne A, Amaratunga EAPD, Udagama MNGPK, Ikuko Ogawa, Kudo Y, Takata T, Tilakaratne WM. Analysis of histological and immunohistochemical differences of oral squamous cell carcinoma in the young and old in Sri Lanka. J Oral Pathol Med. 2007; 36:357-362.

67. Nissanka EH, Amaratunge EAPD and Tilakaratne WM. Clinico-pathological analysis of osteosarcoma of jaw bones. Oral Diseases. 2007; 13:82-87

68. Summers S, Tilakaratne WM, Fortunre F. Renal disease and the mouth. Am J Med. 2007 Jul;120(7):568-73.

69. Okada H, Yamamoto H, Tilakaratne WM. Odontogenic tumours in Sri Lanka; Analysis of 226 cases. J Oral Maxillofac Surg 2007 ;65(5):875-82.

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70. A. Ariyawardena, GJ Panagoda, HN Fernando, ANB Ellepola, WM Tilakaratne, LP Samaranayake. Oral sumucous fibrosis and oral yeast carriage: case control study in Sri Lankan patients. Mycoses 2007 Mar;50(2):116-20.

71. Jona Freysdottir, Sha Zhang, Tilakaratne WM, Farida Fortune. Oral biopsies from patients with orofacial granoulomatosis, with histology resembling Crohn’s disease, have a prominent Th1 environment. Inflamm Bowel Dis 2007 Apr;13(4):439-45.

72. Jayasooriya PR, Illeperuma E, Tilakaratne WM. Undiagnosed tuberculous lymphadenitis in oral squamous cell carcinoma patients. Sri Lanka Dental Journal 2007; 37:99-105.

73. Jayasinghe N, Hewapathirana S, Tilakaratne WM. Cystic metastasis of squamous cell carcinoma. General Dental Parctitioner 2007; 24:41-45.

74. Tilakaratne WM, Klinikowski MF, Takashi Saku, Peters TJ and Saman Warnakulasuriya. Oral submucous fibrosis: Review on aetiology and pathogenesis. Oral Oncology 2006; 42:561-568.

75. Siriwardena BSMS, Kudo Y, Ogawa I, Kitagawa M, Tilakaratne WM, Takata T. Periostin is frequently overexpressed and enhances invasion and angiogenesis in oral cancer. British Journal of Cancer 2006; 95:1396-1403.

76. Siriwardena BSMS, Tilakaratne A, Amaratunge EAPD and Tilakaratne WM. Demographic, aetiological and survival differences of squamous cell in the young and the old in Sri Lanka. Oral Oncology 2006; 42:831-836.

77. Amarapala H, Tilakaratne WM. Leiomyosarcoma of the oral cavity: report of seven cases and review of literature. Oral Oncology (Extra) 2006; 42:14-17.

78. Tilakaratne WM. Synovial sarcoma of the mandible. J Oral Pathol Med 2006; 35:61-63.

79. Jayasuriya NS, Tilakaratne WM, Amaratunge EAPD, Ekanayake MKB. An unusual presentation of rhinofacial zygomycosis due to Cunninghamella sp in an immunocompetent patient: a case report and review of literature. Oral Diseases 2006; 12:67-69.

80. Tilakaratne WM, Sosai CPS. Histopathological review of orofacial angiolymphoid hyperplasia with eosinophilia and Kimura’s disease. Sri Lanka Journal of Medicine 2006; 15:15-20.

81. Tilakaratne WM. Oral Cancer. Journal of Al Reef International Hospital. 2006;4; 6-7.

82. H Utsonomiya, WM Tilakaratne and T Saku. Extracellular matrix remodeling in oral submucous fibrosis: its stage-specific modes revealed by

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immunohistochemistry and in-situ hybridization. J Oral Pathol Med 2005; 34:498-507.

83. Tilakaratne WM and Dissanayake M. Paraneoplastic pemphigus: a case report and review of literature. Oral Diseases 2005; 11:326-329.

84. Tilakaratne WM. Recent advances in autoimmune blisters in the oral mucosa: review. Sri Lanka Dental Journal 2005;35(01)17-22.

85. Jayasinghe N, Tilakaratne WM. A case of Sialo-odontogenic cyst with hyaline bodies and review of literature. Sri Lanka Dental Journal 2005;35(01)28-32.

86. Ariyawardena SPAG, Tilakaratne WM, Dissanayake M. Vithanaachchi N, Basnayake LK, Sitheeque and Ranasinghe MAM. Oral pemphigus vulgais in children and adolescents: review of literature and a case report. Int J of Paediatric Dentistry 2005; 15:287-293.

87. Siriwardena BSMS, Tilakaratne WM, Rajapaksa RMSK. Metastatic transitional cell carcinoma of the urinary bladder to the mandible- a case report. Oral Oncology Extra. 2005;41(2):22-24.

88. Nissanka E.H. Tilakaratne WM Recurrent sebaceous adenoma of parotid gland. Sri Lanka Dental Journal 2004;34(2):92-95.

89. Siriwardena BSMS, Tilakaratne WM and Amaratunge EAPD. A case report of Rosai Dorfman disease of the parotid gland. Sri Lanka Journal of Medicine 2004; 13:41-43.

90. Jayasooriya PR, Saku T, Cheng J and Tilakaratne WM. Cat scratch disease: detection of Bartonella henselae using PCR. Sri Lanka Journal of Medicine 2004; 13:7-11.

91. Dissanayake M, Tilakaratne WM. Clinicopathological analysis of blistering disorders; experience in the Central Province of Sri Lanka. Sri Lanka Journal of Dermatology 2004;8;13-16.

92. Tilakaratne WM, Jayasinghe RD. Pattern of recurrence of Ameloblastoma. Sri Lanka Dental Journal 2004;(1) 20-28.

93. De Silva M.N. Tilakaratne W.M. De Silva Harsha Lal. Bilateral tuberculous ulcers in maxillary tuberosities. Sri Lanka Dental Journal 2004; 34(1): 34-39.

94. Odell EW, Aldred M, Tilakaratne WM et al. Clinico-Pathological conference. Ann Acad Med Singapore 2004; 33: 53-58

95. Jayasooriya PR, Gunarathna I.AN.S. Attygalla A.M., Tilakaratne W.M. Metastatic renal cell carcioma presenting as a clear cell tumour in the head and neck region. Oral Oncology EXTRA (2004) 40 50 – 53.

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96. De Silva MN, Tilakaratne WM, Kosgoda KMS and P Murugadas Giant Plemorphic Adenoma of the Parotid gland. Oral Oncology EXTRA (2004) 40 43-45.

97. Ariyawardena A., Tilakaratne W.M., Ranasinghe A.W., Dissanayake M. Oral psoriasis in an 11-year-old child. Int J Paediatr Dent. 2004 Mar: 14(2): 141-5.

98. Jayasooriya PR, Tilakaratne WM, Abeyratne S, Ranasinghe AW. Focal Epithelial Hyperplasia (Hecks disease) Oral Diseases; 2004 10: 1-4.

99. Siriwardena BSMS, Tilakaratne WM and Rajapaksha RMSK Clear cell odontogenic carcinoma – A case report and review of literature Int J Oral Maxillofac. Surg 2004 Jul; 33 (5): 512-4.

100. Siriwardena BSMS and Tilakaratne WM Oral intravascular papillary endothelial hyperplasia (Masson’s tumour) Clinico pathological analysis. Sri Lanka Dental Journal 2004;34(1): 29-33.

101. Tilakaratne W.M, Siriwardena B.S.M.S., Eosinophilic Ulcer: Clinico-pathological analysis. Sri Lanka Journal of Medicine 2003; 12(1): 11- 15.

102. Siriwardena BSMS, Tilakaratne WM, Rajapaksha RMSK. A case of sebaceous carcinoma of the parotid gland. J Oral Pathol Med, 32(2) 121-123,2003.

103. Tilakaratne WM, Pitakotuwage N. Intra-oral dirofilaria Infection-Report of seven cases. J Oral Pathol Med 2003; 32:502-5.

104. Jayasooriya P.R., Kurose K, Tera M, Sivagnanum K, Siriwardana S, Tilakaratne W.M., Tagami J and Takagi M. Human papillomavirus in Oral Cancer from Sri Lanka: prevalence and relationship with clinico-pathological parameters. Japanese Oral and Med Pathol 2003; 8: 45-50.

105. Gurusinghe SKB, Tilakaratne WM, Rajapakse RMSK and Silva SPI Castleman’s disease of hyaline vascular type: Report of two cases. Sri Lanka Dental Journal 32 (01): 25-27: 2003.

106. Illeperuma E, Tilakaratne WM. Dias DK. Ectomesenchymal chondromyxoid tumour of the anterior tongue. Sri Lanka Dental Journal, 32 (02) 2003: 65-67.

107. Hiroyuki Okada, W.M.Tilakaratne, Hirotsugu Yamamoto. Rhinosporidiosis Occurring in the Soft Palate. Nihon Univ. J. Oral Sci. 28: 290-293,2002.

108. Tilakaratne WM, Pathiraja RM, Jayasinghe RM. Biological behaviour of Pleomorphic adenomas in Sri Lanka– A retrospective study. Sri Lanka Dental J. 31(2) 57-61,2002.

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109. Siriwardena BSMS, Karunatilaka AHTS and Tilakaratne WM. An ameloblastoma developing in a dentigerous cyst. Sri Lanka Dental J 2002: 31(2) 77-78.

110. Siriwardena BSMS, Tilakaratne WM. and Amaratunga EAPD. Histopathological review of two cases of white sponge naevus. Sri Lanka Journal of Medicine 2002; 11(2): 52-54.

111. Dissanayake M. and Tilakaratne WM. A clinico-pathological analysis of pemphigus from Teaching Hospital Kandy. The Sri Lanka Journal of Dermatology, 2001, Volume 5, 26-28.

112. Dissanayake M, Tilakaratne WM, Vitharana KK and Lokunarangoda. Vogt-Koyanagi-Harada Syndrome” Sri Lanka Journal of Dermatology, 2001, 5, 31-32.

113. Jayasekera Sharmini, Arsecularatne SN, Attapattu DN, Kumarasiri R. and Tilakaratne WM Cell mediated immune responses (CMIR) to Rhinosporidium seeberi in mice. Mycopathologia 152: 69-79. 2001.

114. Bandara KMTN, Tilakaratne WM. Relational database management system for reporting histopathological data. Sri Lanka Dental J. 30(2) 37-43, 2001.

115. Tilakaratne WM, Jayasinghe R.D. Comparison of the expression of proliferating cell nuclear antigen (PCNA) in recurrent & non-recurrent ameloblastomas in Sri Lanka. Sri Lanka Journal of Medicine.10 (2): 46-50,2001.

116. Tilakaratne WM. and Dias DK. Xeroderma Pigmentosum (XP): A pre-cancerous condition. Journal of the College of Dentistry and Stomatology, 1999: 8: 01: 1-6.

117. Tilakaratne WM, Odell E. Lock C, Morgan P. Cell proliferation in odontogenic tumours. J of Oral Surgery, Oral Medicine & Oral Pathology 1999; 88: 2: 210.

118. Tilakaratne WM, Odell EW, sherrif M and Morgan PR (1998). Site specificity of histological features of Oral epithelial dysplasia. Journal of Oral Path & Med. August 1998: 27:7; 342-366.

119. Odell EW, Tilakaratne WM, Sherrif M and Morgan P.R (1998). Grading of oral epithelial dysplasia. Selection of definable characteristics. Journal of Oral Path & Med. August 1998: 27:7, 342-366.

120. DW Goodison, RGDM Burr, WM Tilakaratne et al. A case of Benign metastasising pleomorphic adenoma. Journal of Oral Path & Med. 1998; 27: 7: 336-341.

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Research communications/presentations 1. D Jayawardane, NH Senarath, BSMS Siriwardena, WM Tilakaratne. Clinical and

histopathological analysis of concomitant Oral Submucous Fibrosis in oral squamous cell carcinoma presented to the Departmet of Oral Pathology, Faculty of Dental Sciences, University of Peradeniya. National Health Research Symposium 2017, BMICH, Colombo.

2. WAMUL Abeyasinghe, RK De Silva, BSMS Siriwardena, A Samaranayaka, WM Tilakaratne. Depth of invasion as a predictive factor for cervical lymph node metastasis in oral squamous cell carcinoma. National Health Research Symposium 2017, BMICH, Colombo.

3. AK Baddevithana, WMKM Bandara, RD Jayasinghe, BSMS Siriwardena, WM Tilakaratne, RP Illeperuma. Human papilloma virus infection and its correlation with expression of p16 gene in oral potentially malignant disorders and oral cancer. IPURSE, 2017, Peradeniya, Sri Lanka

4. WAMUL Abeyasinghe, PR Jayasooriya, WM Tilakaratne. Natuaral history of oral submucous fibrosis; a clinicopatholgical study. IPURSE, 2017, Peradeniya, Sri Lanka

5. AK Baddevithana, WMKM Bandara, RD Jayasinghe, BSMS Siriwardena, WM Tilakaratne, RP Illeperuma. Expression of p16 gene and HPV oncogene in oral potentially malignant disorders and oral cancer. 8th ASOMP meeting, Vijayawada, India, August 2017

6. HDNU Karunatilaka, BSMS Siriwardena, WM Tilakaratne. Histological parameters and expression of EGFR and β-catenine in oral squamous cell carcinoma: a preliminary study. IPURSE, 2016, Peradeniya, Sri Lanka.

7. AK Baddevithana, RP illeperuma, RD Jayasinghe, BSMS Siriwardena, WM Tilakaratne. Expression of p16 gene in oral potentially malignant disorders and oral cancer: a preliminary study. IPURSE, 2016, Peradeniya, Sri Lanka.

8. WMKM Bandara, RP Illeperuma, KD Kyeong, BSMS Siriwardena, RD Jayasinghe, WM Tilakaratne, K Jin. Expression of γ-h2ax and p53 in oral cancer and oral potentially malignant diseases with areca nut history. IPURSE, 2016, Peradeniya, Sri Lanka.

9. WMKM Bandara, WM Tilakaratne et al. Arecanut induced DNA damage can be reversed by Shumacheria Castaneifolia. World congress on Oral pathology and Medicine, International Association of Oral Pathologists, Chennai, India Sep 2016.

10. WMKM Bandara, RP Illeperuma, WM Tilakaratne et al. Analysis of DNA double

strand damage during oral carcinogenesis in arecanut chewers. International symposium on oral cancer and cancer prevention. Seoul Korea 2015.

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11. WMKM Bandara, RP Illeperuma, WM Tilakaratne et al. Testing efficacy of antioxidant rich herbal extracts in reducing arecanut induced carcinogenesis. Sri Lanka Medical association 129th anniversary international Medical congress, 2016 Colombo.

12. WMAUL Abeysinghe, WM Tilakaratne et al. A case of deep fungal infection presenting as necrotising stomatitis in an immunocompromised patient. Annual Scientific sessions of Sri Lanka Dental Association 2016.

13. HGRN Weerasinghe, BSMS Siriwardena, RD Jayasinghe, WM Tilakaratne. Plasma cell mucositis affecting oral mucosa; report of 11 cases. IPURSE, 2015, Perdeniya, Sri Lanka.

14. RK De Silva, BSMS Siriwardena, WM Tilakaratne. The usefulness of tumour thickness in predicting nodal metastasis of oral squamous cell carcinoma. IPURSE, 2015, Perdeniya, Sri Lanka.

15. HDNU Karunathilaka, BSMS Siriwardena, WM Tilakaratne.Analysis of the

significance of pattern of invasion in relation to oral squamous cell carcinoma. IPURSE, 2015, Perdeniya, Sri Lanka.

16. JDR Perera, RD Jayasinghe, R Sivakanesan, BMR Bandara, WM Tilakaratne. Antioxidant levels in relation to malignant transformation of oral submucous fibrosis; a preliminary study. IPURSE, 2014, Perdeniya, Sri Lanka.

17. RP Illeperuma, YJ Park, WM Tilakaratne, JY Kim, J Kim. Elucidating mechanisms inducing oxidative stress by areca nut in oral mucosa. IPURSE, 2014, Perdeniya, Sri Lanka.

18. BSMS Siriwardena, RP Illeperuma, DSY Jayathilake, TN Pitakotuwage, PVR Kumarasiri, AM Attygala, RD Peiris, A. Tilakaratne, WM Tilakaratne. Anlysis of oral cancer cases of Sri Lanka for 13 years. 17th International Congress on Oral pathology and Medicine, Istanbul, Turkey May 2014.

19. Retrospective analysis of oral cancer cases for 13 years. BSMS Siriwardena, RP Illeperuma, DSY Jayathilake, TN Pitakotuwage, PVR Kumarasiri, AM Attygala, RD Peiris, WM Tilakaratne. ASOMP 2014, Hyderabad, India.

20. RMAR Rajapakshe, RW Pallegama, PR Jayasooriya, BSMS Siriwardena, DK Dias, AM Attygalla, S Hewapathirana, MKB Ekanayake, JU Weerasinghe, WM Tilakaratne. A retrospective analysis to determine factors contributing to the survival of patients with oral squamous cell carcinoma. SLAOMS sessions 2013. Page 28.

21. B.S.M.S. Siriwardena, I.K. Rambukewela, TN Pitakotuwage, MNGPK Udagama,

PVR Kumarasiri, W.M. Tilakaratne Pattern of nodal metastasis of oral squamous cell carcinoma. SLAOMS sessions 2013. Page 29-30.

22. BSMS Siriwardena, RP Illeperuma, DSY Jayathilake, TN Pitakotuwage, PVR

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Kumarasiri, AM Attygala, RD Peiris, WM Tilakaratne. Analysis of demographic data of 4394 cases of oral squamous cell carcinoma. SLAOMS sessions 2013. Page 31

23. RMSGK Rasnayake, BSMS Siriwardena, RLPR Liyanage, PVR Kumarasiri,

WM Tilakaratne. Relationship between age, site and metastasis of oral squamous cell carcinoma. SLAOMS sessions 2013. Page 32

24. WKL Perera, T Jayawardena, NS Wadusinghearachchi, BSMS Siriwardena, AM

Attygala, DK Dias, WM Tilakaratne. Significance of status of excision margins on survival of oral squamous cell carcinoma. SLAOMS sessions 2013. Page 33

25. RP Illeperuma, YJ Park, WM Tilakaratne, J Kim. Fibroblasts are implicated in Arecanut induced carcinogenesis via oxidative DNA damage and aneuploidy. FDI/CDA/SLDA International Dental Congress, 2013.

26. R Ekanayaka, RD Jayasinghe, MAM Sitheeque, H Amarasinghe, WM Tilakaratne. Intralesional corticosteroids as a treatment for restricted mouth opening in oral submucous fibrosis. FDI/CDA/SLDA International Dental Congress, 2013.

27. P. Lankathilake, M. Al Sayooni, W. Tilakaratne, And A.R. Tappuni, Evaluation of Oral Submucous Fibrosis in East London. Annual Sessions IADR 2012, Brazil.

28. RP Illeperuma, YJ Park, WM Tilakaratne, J Kim. A novel approach to understand carcinogenesis in oral submucous fibrosis. 125th Anniversary International Medical Congress of Sri lanka Medical Association, 2012.

29. S.R. Vartoukian, WM. Tilakaratne, M. Bombardieri, N. Seoudi, N. Sutcliffe, K.M. Piper, F. Fortune, and A.R. Tappuni. SOCS3 Dysregulation in Primary Sjogren’s Syndrome. Annual Sessions IADR 2012, Brazil.

30. Rasika P Illeperuma, Young Jin Park, Hwa K Son, Jin M Kim, Da-Woon Jung, WM Tilakaratne, Jin Kim. Implications of cytokines released from gingival fibroblasts exposed by areca nut extract in carcinogenesis. American Academy of Cancer Research 2012.

31. Rasika P Illeperuma, Young Jin Park, Hwa K Son, Jin M Kim, Da-Woon Jung, WM Tilakaratne, Jin Kim. Utilization of hTERT immortalised gingival fibroblasts in an in vitro model to elucidate cytokine secretion of submucosal fibroblasts in oral submucous fibrosis. The Korean J of Oral and Maxillofacial Pathology. 2011;35 (2).

32. Rasika P Illeperuma, Young Jin Park, Hwa K Son, Jin M Kim, Da-Woon Jung, WM Tilakaratne, Jin Kim. Investigating the carcinogenesis of oral submucous

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fibrosis with special reference to the role of cytokines released from submucosal fibroblasts. Australian and New Zealand Association of Oral and Maxillofacial Surgeons conference 2011, Melbourne, Australia.

33. Rasika P Illeperuma, Young Jin Park, Hwa K Son, Jin M Kim, Da-Woon Jung,

WM Tilakaratne, Jin Kim. Implications of cytokines released from gingival fibroblasts exposed by areca nut extract in carcinogenesis. International cancer meeting, Yonsei Unversity, School of Dentistry, Seoul, Korea 2011.

34. BSMS Siriwardena, TMPB. Tennakoon, RLPR Liyanage, NS Wadusinghearachchi WM Tilakaratne. Analysis of 1674 cases of odontogenic tumours in Sri Lanka; Changes in relative frequency according to 2005 WHO classification. National conference of Indian Association of Oral Pathologists, Hyderabad, India, November 2011.

35. BSMS Siriwardena, IK Rambukewela, WM Tilakaratne Analysis of the relationship between status of nodal metastasis, clinical stage and histological parameters of oral squamous cell carcinoma. Annual Scientific Sessions, University of Peradeniya 2011.

36. BSMS Siriwardena, TMPB Tennakoon, WM Tilakaratne. Relative frequency of odontogenic tumours in Sri Lanka: analysis of 1674 cases. Annual Scientific Sessions, University of Peradeniya 2011.

37. BMHSK Banneheka, MSM Kularatne, WM Tilakaratne. A survey on tobacco

use and awareness on tobacco related health hazards among teenage students. Annual Scientific Sessions, University of Peradeniya 2011.

38. Jayasinghe RD, Jayashankar S and Tilakaratne WM. Clinical and Radiological features of ossifying fibromas of jaws; analysis of 27 cases. Annual Scientific Sessions of Sri Lanka Dental Association Kandy branch, October 2011.

39. Farook FF, Perera WKL, Dassanayake BK, Tilakaratne WM, Tilakaratne A. Comparison of the periodontal status and periodontal treatment response among smokers and non- smokers. Annual Scientific Sessions of Association of Specialists in Restorative Dentistry, 2011.

40. RMAR Rajapakshe, BSMS Siriwardena, WM Tilakaratne et al. A retrospective

analysis to determine factors influencing the management of patients with oral squamous cell carcinoma. Asia Pacific dental congress, Colombo 2010.

41. BSMS Sirirwardena, MPB Herath, DSY Jayathilake, WM Tilakaratne et al.

Demographic and histological variations of oral squamous cell carcinoma in Sri Lanka. Asia Pacific dental congress, Colombo 2010.

42. BSMS Sirirwardena, EM Deraz, T Takata, WM TIlakaratne, Y Kudo.

Stromalysin-2 promotes invasion in oral squamous cell carcinoma. Annual Scientific sessions, University of Peradeniya 2010.

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43. Rasika P Illeperuma, Young Jin Park, Jinmi Kim, Da-Woon Jung, WM Tilakaratne, Jin Kim. Cytokine expression by the treatment of areca nut extract in cultured fibroblasts: comparision between normal oral fibroblasts and hTERT transfected fibroblasts. 15th International Congress on Oral Pathology and Medicine, Seoul, Korea August 2010.

44. Rasika P Illeperuma, Young Jin Park, Hwa K Son, Jin M Kim, Da-Woon Jung,

WM Tilakaratne, Jin Kim. Cytokines might play a key role in carcinogenesis of oral submucous fibrosis. International cancer meeting, Yonsei Unversity, School of Dentistry, Seoul, Korea 2010.

45. K. Moutasim, V. Jenei, K. Sapienza, D. Marsh, J. Marshall, F. Fortune, W.M. Tilakaratne, I. Hart, and G. Thomas. The Role of αvβ6 Integrin in Oral Submucous Fibrosis. International Association for Dental Research 2010, Barcelona, Spain.

46. G. Pitiyage, S. Prime, W. Tilakaratne, F. Fortune, and E.K. Parkinson. Increased senescence and altered collagen metabolism in oral submucous fibrosis. International Association for Dental Research 2010, Barcelona, Spain.

47. I Prathapasinghe, Attygalla AM and Tilakaratne WM. A case of Foregut cyst of the oral cavity. Annual scientific sessions of Association of Oral and Maxillofacal Surgeons of Sri Lanka 2009

48. Illeperuma R, Ryu MH, Tilakaratne WM, Kim J. Evaluation of PCNA index and

expressions of TGF-Beta-1, MMP1 and TIMP1 in oral submucous fibrosis. Meeting of the Korean Association of Oral Pathologists, 2009

49. Illeperuma R, Ryu MH, Kim KY, Tilakaratne WM, Kim J. Effects of fibrosis and

extracellular matrix remodelling in oral submucous fibrosis on its malignant transformation of the epithelium: Immunohistochemical evaluation by testing expressions of TGF-beta 1, MMP 1, TIMP 1 and PCNA index. The Korean J of Oral and Maxillofacial Pathology 2009; 33:120

50. Illeperuma R, Ryu MH, Kim KY, Tilakaratne WM, Kim J. Influence of fibrosis

and extracellular matrix remodelling in oral submucous fibrosis on carcinogenesis: Immunohistochemical evaluation using Sri Lankan biopsy tissue. Asian Society of Oral Pathology, Beijing, China, November 2009.

51. Siriwardena BSMS, Kudo Y, Takata T, Tilakaratne WM. Periostin promotes

metastasis by enhancing angiogenesis and lymphangiogenesisis in oral squamous cell carcinoma. Annual Scientific sessions, University of Peradeniya 2009.

52. Jayasooriya PR, Jayasinghe KAN, Tilakaratne WM. Relationship between

thickness of fibrosis and epithelial dysplasia in oral submucous fibrosis. Annual Scientific sessions, University of Peradeniya 2009.

53. Gunawardhana KSND, Jayasooriya PR, Rambukewela IK, Tilakaratne WM. A

retrospective analysis of mandibilular and maxillary ameloblastomas: A

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comparative study. squamous cell carcinoma. Annual Scientific sessions, University of Peradeniya 2009.

54. Dissanayaka WL, Jayasooriya PR, Kumarasiri PVR, Tilakaratne WM.

Comparison of histopathological features of synchronous and single primary oral Squamous cell carcinomas. squamous cell carcinoma. Annual Scientific sessions, University of Peradeniya 2009.

55. Rasika P Illeperuma, Mi Heon Ryu, Ki Yeol Kim, Jin Kim, W.M. Tilakaratne

Role of TGF Beta-1, MMP-1, TIMP-1 and PCNA in Pathogenesis and Malignant Transformation of Oral Submucous Fibrosis. Annual Scientific Sessions, University of Peradeniya 2009.

56. G. Pitiyage, K.P. Lim, S. Prime, W. Tilakaratne, F. Fortune, and E.K. Parkinson.

Senescent mesenchymal cells accumulate in tumour susceptible oral fibrosis. British Society of Dental Research metting, 2009, Glasgow, UK.

57. G. Pitiyage, E. Hagi-Pavli, F. Fortune, W. Tilakaratne, and E. Parkinson. Oral

Submucous Fibrosis-Events in The Extracellular Matrix. The Pan European Federation of the International Association for Dental Research (September 10-12, 2008), London, UK.

58. K.A. Moutasim, D. Mirza, D. Marsh, V. Jenei, S. Dickinson, W. Tilakaratne, G.J

Thomas. 0816 Integrin αvβ6 promotes TGF-β1-dependent myofibroblastic transdifferentiation in oral submucous fibrosis. The Pan European Federation of the International Association for Dental Research (September 10-12, 2008), London, UK.

59. Farook F, Jayasinghe RD, Tilakaratne A, Tilakratne WM. Clinicopathological

analysis of Odontogenic Keratocyst. Annual academic sessions of SLDA Kandy Branch 2008.

60. Rasika Illeperuma, Mi-Heon Ryu, WM Tilakaratne, Jin Kim. Evaluation of

PCNA index and expressions of TGF-1, MMP-1 and TIMP-1 in oral submucous fibrosis. The Korean J of Oral and Maxillofacial Pathology. 2008;32 (4).

61. Pitiyage G, Dias DK, Kumarasiri R, Ariyawardana A, Tilakaratne WM.

Significance of clinical and histological parameters on survival of oral squamous cell carcinoma. 14thInternational congress, International Association of Oral Pathologists, San Francisco, USA, June 2008.

62. Tilakaratne WM, Jayasuriya PR, Tennkoon TMPB and Saku T. Epithelial

salivary gland tumours in Sri Lanka- Retrospective study of 713 cases. Annual scientific sessions of University of Peradeniya, 2008.

63. E. Hagi-Pavli, A. Cruchley, L. Brown, W. Tilakaratne, A. Ariyawardena, M.-T.

Teh, A Waseem, K. Parkinson, and F. Fortune.. Effects of areca extract, arecaidine and lime on oral mucosa. The Joint Scientific Meeting of BDSR and NOF (3rd - 5th April 2007), Durham, England.

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64. Tilakaratne WM, Ariyawardana A, Teck The, Pitiyage G, Parkinson EK, Fortune

F et al. Up regulation of HIF1 alpha in the progression and malignant transformation of oral submucous fibrosis. First world congress on Oral Oncology, Amsterdam, Netherlands- May 2007.

65. Pitiyage G, E.Hagi-Pavli, F.Fortune, W.M. Tilakaratne and E.K.Parkinson.

Fibroblasts from oral submucous fibrosis patients show alteration in TGF-β release and collage metabolism. British Society of Oral Pathology and Medicine, London, May 2007.

66. Amarapala H, Tilakaratne WM, Amaratunga EAPD. Malignant connective tissue

neoplasms in the craniofacial region. Annual academic sessions of SLDA 2006

67. Pitiyage G, Dias DK, Kumarasiri R, Ariyawardana A, Tilakaratne WM. Oral squamous cell carcinoma: The significance of excision margins in the recurrence and survival. Asia Pacific Oral cancer congress- Malaysia-Feb, 2006.

68. Tilakaratne WM, Siriwardena BSMS, Yasusei Kudo, Ikuko Ogawa, Takashi

Takata. VEGF-C expression, Intratumoral and peritumoral lymphangiogenesis in oral squamous cell carcinoma. IADR, Dublin, 2006

69. Siriwardena BSMS, Tilakaratne WM, Tilakaratne A, Amaratunge EAPD.

Demographic, aetiological, histopathological and survival differences in the younger and older oral squamous cell carcinoma patients in Sri Lanka. Scientific Sessions of Asian Society of Oral and maxillo-facial Pathology, Seoul, Korea. May 2005.

70. Jayasooriya PR, Suraweera AK, Saku T, Tilakaratne WM. Immunohistochemical

expression of BCL-2 and BAX proteins in basaloid squamous cell carcinoma. Annual Scientific Sessions of Sri Lanaka Dental Association-2005.

71. Tilakaratne WM, Ida H, Cheng J, Maruyama S, Saku T. Differential expression

modes of matrix metalloproteinases (MMPs) in oral borderline malignancies: an aid for histopathological recognition of dysplastic cell zones. 16th annual meeting of the Japanese society of Oral pathology, Morioka Japan 2005; page 48.

72. Jayasooriya PR, Suraweera AK, Saku R, Tilakaratne WM.

Immunohistochemical expressions of BCL2 and BAX proteins in basaloid squamous cell carcinoma. SLDA 2005: p32.

73. Siriwardena BSMS, Tilakaratne WM, Saito A, Kitagawa M, Ogawa I, Takata T.

A case of palatal tumour. 6th salivary conference, Tokyo, Japan, 2004.

74. Nissanka EH, Tilakaratne WM. Histopathological and radiological comparison of unicystic ameloblastoma. SLDA annual sessions 2004.

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75. Illeperuma E, Tilakaratne WM. Undiagnosed tuberculous lympherdenitis in cervical block dissection. SLDA annual sessions 2004.

76. Jayasooriya PR, Suraweera AK, Tilakaratne WM. Cytokeratin 19 expression as a

new histodiagnostic marker to differentiate unicystic ameloblastoma from dentigerous cyst. SLDA annual sessions 2004.

77. Nandasena BGTL, Jayawardena JACK, Suraweera AK, Tilakaratne WM,

Nanayakkara CD. Localization of cholinesterase enzyme and its putative role in human tooth morphogenesis. SLDA annual sessions 2004.

78. Siriwardena BSMS, Tlakaratne WM, Tilakaratne A, Amaratunga EAPD. A

comparative study of oral squamous cell carcinoma in the young and the old - Histopathological analysis. SLDA annual sessions 2004.

79. De Silva MN, Tilakaratne WM, Edirisinghe JS, Jayasinghe SK. A case of

cysticercosis the oral cavity. SLDA annual sessions 2004.

80. Nandasena BGTL, Jayawardena JACK, Suraweera AK, Tilakaratne WM and Nanayakkara CD. Localization of non neuronal contribution of cholinesterase enzyme in human tooth morphogenesis. Peradeniya University Research Sessions 2004.

81. Jayasooriya PR, Saku T and Tilakaratne WM. Detection of Bartonella henselae

DNA by PCR to confirm the histopathological diagnosis of cat scratch disease. Peradeniya University Research Sessions 2004.

82. Ariyawardana A, Vithanaarachchi N, Panagoda G, Tilakaratne WM, Fernando HN

and Samaranayake LP (2004). Oral candidal carriage in oral submucous fibrosis (OSMF) – a case control study. Peradeniya University Research Sessions 2004.

83. H Utsunomiya, H Ida, Tilakaratne WM, Cheng J and Saku T. (2004) Extracellular

matrix remolding in oral submucous fibrosis progression: a structural background for oral carcinogenesis due to chewing habits. 15th Annual Meeting of the Japanese Society for Oral Pathology.

84. Nissanka E.H., Tilakaratne WM, Amaratunga E.A.P.D. Histopathological analysis

of osteosarcoma of jaw bones. Annual Scientific Sessions of Sri Lanka Dental Association June 2003.

85. De Silva M.N., Tilakaratne W.M., Amaratunga E.A.P.D. Analysis of six hundred

salivary tumours. Annual Scientific Sessions of Sri Lanka Dental Association June 2003.

86. Jayasooriya N.S.S. Tilakaratne W.M., Amaratunga E.A.P.D. Clinico-pathological

analysis of five cases of zygomycosis. Annual Scientific Sessions of Sri Lanka Dental Association June 2003.

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87. Jayasooriya PR, Rambukewela I.K, Nanayakkara P.G.C.L., Kurose K, Tilakaratne W.M. Detection of human papilloma virus DNA in oral squamous cell carcinoma. Annual Scientific Sessions of Sri Lanka Dental Association June 2003.

88. Jayasooriya PR, Rambukewela IK, Abeyratne S, Tilakaratne WM. Focal Epithelial

Hyperplasia (Heck’s disease), report of a case with detecting HPV using PCR Annual Scientific Sessions of Sri Lanka Dental Association June 2003.

89. Loganathan P, Peiris AM., Tilakaratne W.M. Papillary endothelial hyperplasia

(Masson’s Tumour) Annual Scientific Sessions of Sri Lanka Dental Association June, 2003.

90. Jayasinghe RD, Tilakaratne WM, Pathiraja RM Clinico-pathological analysis of

Odontogenic cysts in Sri Lanka for a period of twelve years. Annual Sessions of the college of Dentistry and stomatology- 2003.

91. Tilakaratne WM, Bandara DMSM, Siriwardena BSMS. The effects of different

types of tobacco habits as aetiological factors in Oral squamous cell carcinoma in Sri Lanka. 12th world congress on tobacco or health, Helsinki, Finland 2003.

92. Ekanayake K, Tilakaratne WM, Ekanayake M. Paraganglioma metstasising in the

mandible-A case report. Annual sessions of the college of Dentistry and stomatology- 2003

93. Dissanayake M, Tilakaratne WM Thamilvannan N. Clinico-Pathological analysis

of autoimmune blistering disorders- Experience in the central province of Sri Lanka. South Asian regional conference of Dermatology, Venereology and Leprosy. Scientific sessions, 2003.

94. Jayasooriya PR, Nanayakkara PGCL, Tilakaratne WM. Human papilloma virus

(HPV) detection rate in betel quid induced leukoplakia and Oral squamous cell carcinoma. University research sessions – Peradeniya, 2003.

95. Siriwardena BSMS, Tilakaratne WM, Amaratunge EAPD and Tilakaratne A. A

comparative study of Oral squamous cell carcinoma in the young and the old. University research sessions – Peradeniya, 2003.

96. Tilakaratne WM, Karunadasa WMUR, Karunatilaka AHTS. A case report-

Kikuchi’s disease (Lymphadenitis showing focal reticulum cell hyperplasia) University research sessions – Peradeniya, 2003.

97. Dissanayake M, Tilakaratne WM. Autoimmune subepidermal blistering disorders

seen at Teaching Hospital, Kandy – A preliminary report. Annual academic sessions & joint meeting with German Dermatological Society held from 14-17th February 2002. Colombo & Kandy.

98. Tilakaratne WM. Pathiraja RM. Immunohistochemical analysis of recurrent and

non-recurrent pleomorphic adenomas in Sri Lanka”. 11th Biennial Congress on Oral Pathology and Medicine, Singapore, 2002.

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99. Pathiraja RM, Tilakaratne WM, Jayasinghe RD and Biological behaviour of

pleomorphic adenomas in Sri Lanka. Annual Scientific Sessions of Sri Lanka Dental Association June 2002.

100. Tilakaratne WM, Amaratunge EAPD, Suraweera AK, Histopathology and

immunohistochemical analysis of Salivary duct carcinoma. The College of Pathologists, Sri Lanka, Annual Academic Sessions 2002.

101. Peiris MKA, Fernando R, Tilakaratne WM, Intra abdominal desmoplastic small

round cell tumour. The College of Pathologists, Sri Lanka, Annual Academic Sessions 2002.

102. Soysa HNS, Nakakuki K, Suraweera AK, Tilakaratne WM, CD44 as a prognostic

marker in oral squamous cell carcinoma. Proceedings of the annual research sessions, University of Peradeniya, Sri Lanka, 2002.

103. Panagoda GJ, Tilakaratne WM, Jayatilake S, Fernando HN, Formalin Associated

candidosis and man. Proceeding of the annual research sessions, University of Peradeniya Sri Lanka 2002.

104. Utsunomiya H, Ida H, Oshhiro K, Tilakaratne WM, Saku T. Remodelling of

extracellular matrix during the progress of oral submucous fibrosis. Jap J of Oral Biology 44 (5) 2002: 167.

105. Tilakaratne WM, Dias DK, Siriwardena BSMS. Candidiasis and Oral epithelial

dyspalsia. Annual research sessions of the University of Peradeniya, 16th November 2001.

106. Jayasinghe RD, Tilakaratne WM, Suraweera AK. Comparison of the expression

of proliferating cell nuclear antigen (PCNA) in recurrent and non-recurrent ameloblastomas: An immunohistochemical study Annual Research Sessions of the University of Peradeniya, 16th November 2001.

107. Soysa HNS, Tilakaratne WM Eosinophilic host response as a prognostic variable

in oral Squamous cell carcinoma Annual Research Sessions of the University of Peradeniya held on 16th November 2001.

108. Tilakaratne WM, Arsecularatne SN Innate immunity to Rhinosporidium seebri in

Guinea Pigs. Annual Research Sessions of the University of Peradeniya, 6th November 2001.

109. Jayasinghe RD, Tilakaratne WM Pattern of recurrence of Ameloblastoma in Sri

Lanka. International Dental Congress 2001, Colombo SriLanka. 110. Siriwardena BSMS, Tilakaratne WM, Nishantha TMRA Histological grading of

mucoepidermoid carcinoma of salivary glands in prognosis and survival. International Dental Congress 2001, Colombo, Sri Lanka.

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111. Attygala AM, Tilakaratne WM Sialo-odontogenic cyst. International Dental Congress, 2001, Colombo, Sri Lanka.

112. Tilakaratne WM, Siriwardena BSMS. Value of individual histological features in

predicting the behaviour of Oral Cancer. International Dental Congress, 2001, Colombo, Sri Lanka.

113. Nakakuki K, Tilakaratne WM. Immediate frozen section is a strong diagnostic

tool to assess the margins in Oral cancer resection. International Dental Congress, 2001, Colombo, Sri Lanka.

114. Shamini Jayasekara, Arsekularatne SN, Atapattu DN, Kumarasiri PVR,

Tilakaratne WM. Cell mediated immune response (CMIR) to Rhinosporidium Seeberi in experimental mice. Annual acedemic sessions KSM February 2001.

115. Deepani MLANR, Tilakaratne WM and Alahakoon J. An oral carcinoma in a

Jaguar – A case Report. Proceedings of the Annual Research Sessions, University of Peradeniya, Vol.6, November 16, 2001.

116. Tilakaratne WM, Siriwardena BSMS. Impact of histological parameters on

prognosis of oral squamous cell carcinoma. Faculty of Dental Sciences, Research sessions 29th October 2000.

117. Siriwardena BSMS, Tilakaratne WM. Is the pattern of invasion a reliable

predictor of metastasis of Oral Cancer? Proceedings of the University of Peradeniya Annual Research Sessions 2000, vol. 5: 87-93

118. Arsecularatne G, Dissanayake M, Tilakaratne WM. Rajapakse RMSK. A

Clinical and immunohistochemical analysis of patients with bullous dermatoses. Annual academic Sessions of Sri Lanka Association of Dermatologists 2000.

119. Tilakaratne WM, Dissanayake M. Aresecularatne G. Immunopathology of

autoimmune dermatoses in Sri Lankan Patients. Annual Sessions of the College of Dermatologists. 2000.

120. Tilakaratne WM. Cell proliferation in odontogenic tumours. Annual Scientific

Sessions. Sri Lanka Dental Association, 1999. 121. Tilakaratne WM, Mendis BRRN and Amaratunga EAPD Assessment of

epithelial dysplasia in oral submucous fibrosis (OSMF) Annual Sessions of the Kandy Society of Medicine February 1995.

122. Tilakaratne WM Malignant melanoma of the oral cavity, Annual scientific

sessions of Sri Lanka Dental Association, Kandy branch- 1995.

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Supervision of Research and Research Grants

1. Supervision of numerous MPhil, MSc and PhD projects both locally and internationally.

2. Strategic investigation into the standardization of oral pathology and the trend toward specialization of Oral Pathologists in Asia by a Grant-in-Aid for Scientific Research from the Japan Society for the Promotion of Science: 13,390,000 JPY. (Collaborative Project with Japanese and Malaysian counterparts)

3. New Asian Oral Health Project - Prevention of Oral Cancer.

(Collaborative Project with Hokkaido, Japan): 100,000,000 JPY from Japan Society for the Promotion of Science.

4. Research grant from Sri Lanka Dental Association for the project titled

“comparative study of oral cancer in the young and old” 5. Research grant from Sri Lanka Dental Association for the project titled

“Antioxidant levels in Oral cancer and Oral submucous fibrosis” 6. Research grant from National Research council of Sri Lanka (Rs 7

Million) for the project titled “Analysis of the significance of invasive front characteristics in relation to prognosis of oral squamous cell carcinoma”

Present research areas and Collaborative Projects

1. Oral submucous fibrosis; Carcinogenesis in OSF 2. Oral squamous cell carcinoma: Prognostic markers 3. Salivary gland tumours 4. Odontogenic tumours

Project on Oral Submucous fibrosis: Yonsei University, Seoul, South Korea. Project on Oral Submucous fibrosis: University of Niigata, Japan. Project on Oral Cancer and Oral Submucous fibrosis: Queen Mary, University

of London, UK. Project on Oral Cancer: University of Southampton, UK. Project on Oral Cancer: University of Hiroshima, Japan. Project on HPV and Oral cancer: University of Kentucky, USA.

Workshops/Consultancies (Contributed as coordinator or as a resource person)

1. Reviewer for the Medical research council of Singapore, 2017-18

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2. Resource person for the workshop on Head and Neck Pathology organised by College of Pathologists of Sri Lanka, October, 2017 at SLMA, Colombo

3. Resource person as a WHO expert on “Inter country meeting on smokeless tobacco policy” Delhi, India, August 2107.

4. Workshop on ethics in conducting and publishing research organised by Faculty of Medicine, University of Peradeniya July 2017. Delivered a lecture titled Ethics in publishing research.

5. Member of the tumour Board on Dysplasia at the 6th World Oral Cancer Congress by International Academy of Oral Oncology (IAOO), May 2017, India.

6. Reviewer for New Zealand Dental Association research fund

7. Consultant for the development of Head and Neck Cancer reporting data set by International Collaboration on cancer reporting 2016.

8. Resource person for the Oral Health promotion session organised by Ministry of Health and National cancer control programme. Nuwaraeliya. Jan, 2015.

9. Resource person for the workshop conducted by College of Stomatology and Dentistry in Sri Lanka. “How to write/publish a research article. Feb, 2015, Colombo.

10. Resource person for the workshop on Ward and peri-operative management in OMF Sirgery conducted by Ministry of Health in Kurunegala. Jan, 2015.

11. Resource person for the workshop on Research proposal writing conducted by Faculty of Medicine, University of Peradeniya, March 2015.

12. Resource person for the “Training course for Master trainees in Breast, cervical, colorectal and oral cancer early detection and control” organised by International Agency for Research on Cancer (IARC) and NCCP Sri Lanka. June, 2015.

13. Resource person for the workshop on “Management of Salivary gland diseases” organised by Sri Lanka Association of Oral and Maxillofacial surgeons. May 2015 Colombo.

14. Expert Group Consultation on Smokeless Tobacco (SLT) use and Public Health in South East Asia Region (SEAR) Countries, WHO, 2015

15. Resource person for Oral and maxillofacial pathology slide seminar, University of Malaya, Kuala Lumpur, Malaysia, August 2015.

16. Chairman of the smokeless tobacco sub-committee in the National Authority on Tobacco and Alcohol (NATA), Sri Lanka 2015.

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17. Member of the Professional conduct committee of the Sri Lanka Medical

Council of Sri Lanka, 2015 to date.

18. Member of the Preliminary proceedings committee of Sri Lanka Medical Council, 2015 to date.

19. Co-Editor of the booklet on “Guideline for management of oral potentially malignant disorders 2015

20. Member of the National Committee on Research and Development for the Health sector, 2014.

21. Conducted the Oral Pathology study day for MD Pathology trainees and Consultant Pathologists, Faculty of Dental Sciences, University of Peradeniya, 26th April 2014.

22. Workshop for Postgraduate trainees conducted by College of Dentistry and Stomatology of Sri Lanka. Lecture titled “Research; is it necessary?” September 2014.

23. Consultant for the development of the national research cadre for Sri Lanka; 2013.

24. Tilakaratne WM, Resource person for the Workshop titled “Ward and peri operative management in OMF Surgery, Sri Lanka Association of Oral and Maxillofacial Surgeons and Kurunegala Clinical Society Nov, 2013.

25. Pre-Congress Workshop on “Cancer Genetics – Diagnostics, Prognostication and Pharmacogenomics” Sri Lanka Medical Association 126th Anniversary International Medical Congress. A Lecture titled “The challenges of identifying a molecular biomarker for oral cancer - the current status and future directions”. July, 2013.

26. Consultative workshop for the finalization of National policy and strategic framework on prevention and cancer control in Sri Lanka. 25th September, 2012, Colombo Sri Lanka.

27. Consultant for the development of national guidelines for the management of oral precancer (OPMD) ; 2012-13.

28. Consultant for the development of national guidelines for the management of oral cancer; 2012-13.

29. Multidisciplinary workshop on management of oral cancer organised by Sri Lankan Association of Oral and Maxillofacial Surgeons October 2011.

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30. World works shop (WWOM V) on Oral Medicine: 21st -23rd September 2010 in London, UK in the capacity of a consultant for world reviews on Oral Medicine.

31. Workshop on Salivary gland diseases organised by Badulla Clinical Society, 2010

32. Study day of the College of Pathologists of Sri Lanka. Conducted a workshop on odontogenic tumours and Salivary Tumours-March 2008

33. Diagnostic oral pathology courses for Japanese trainee oral pathologists in Japan. 2005

34. Third country training programme in collaboration with JICA. Course coordinator for the course on diagnostic oral and maxillo-facial pathology-2003.

35. Workshop on tobacco cessation to family health workers, teachers, dental student and dentists. 2003

36. Training programme for neighbouring countries. Course coordinator for the course on diagnostic oral and maxillo-facial pathology-2002

37. Workshop on screening of oral mucosal diseases for Japanese Dental hygienists. 2002

38. Tilakaratne WM conducted the workshop on special techniques to include routine special stains, immunohistochemistry and immunofluorescence. Workshop for MD (Pathology) trainees in collaboration with the Postgraduate Institute of Medicine held on 23rd September 2000.

39. Tilakaratne WM Co-author of the manual for the workshop. Special staining

techniques to include routine Special stains, immunohistochemistry, and immunofluorescence for MD (Pathology) trainees conducted in collaboration with the Postgraduate institute of Medicine held on 23rd September 2000.

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Research /Academic Awards and Orations

1. Presidential Research Award from the President of Sri Lanka in 2015.

2. CVCD Excellence Award for the Most Outstanding Senior Researcher in Health Sciences including medical, Dental Sciences, Veterinary Sciences and Allied Health Sciences in Sri Lanka, 2014.

3. Guest of honour and key note speaker titled “Beyond mechanical dentistry” SLDA, annual regional scientific sessions, Galle, Sri Lanka August 2014.

4. Award for the best research paper at the annual scientific sessions of Sri Lanka Association of Oral and Maxillofacial Surgeons of Sri Lanka, 2013.

5. National Research Council Merit Award for Scientific publication 2013.

6. Guest of honour at the 6th Annual Scientific Sessions of Galoya Nimna Clinical Society. Oct, 2013.

7. Oration of the College of Dentistry and Stomatology of Sri Lanka “Oral cancer in Sri Lanka; future and beyond for better cure” 2013.

8. Awarded “Sir Thomas Key Sidey visiting Professor” Faculty of Dentistry, University of Otago, New Zealand, 2013.

9. Daphne Attygalle Prize for the best research paper in Cancer at the Sri Lanka Medical Association 125th Anniversary International Medical Congress, Colombo, Sri Lanka, 2013.

10. Delivered the Keynote address titled “Why cancer research? Sri Lankan perspective” at the first National Symposium on cancer in Sri Lanka organised by National Cancer Control programme 2013.

11. Presidential Research Award from the President of Sri Lanka in 2012.

12. Recipient of the KSM Life Time Health Research Award and Oration at the Foundation sessions of KSM, Kandy, Sri Lanka 2012.

13. Professor Bambaradeniya Memorial Oration 2012. Sri Lanka Dental Association, Kandy branch titled “Oral potentially malignant disorders; an attempt to understand and combat the enemy”

14. Oration of the Kandy Society of Medicine (KSM Oration-2012) on “Oral cancer and precancer; novel markers in malignant transformation and prognosis.

15. Presidential Research Award from the President of Sri Lanka in 2011.

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16. Inaugural Gold Medal Oration of Chennai Dental Research Foundation on “areca nut products - a less known cause of oral cancer; an emerging problem of the young” 2010, India.

17. Presidential Research Award from the President of Sri Lanka in 2010.

18. Presidential Research Award from the President of Sri Lanka in 2009.

19. Presidential Research Award from the President of Sri Lanka in 2008.

20. Presidential Research Award from the President of Sri Lanka in 2007.

21. Placed second among the Sri Lankan Researchers in the Science citation index published by National Research Council for the year 2006.

22. Presidential Research Award from the President of Sri Lanka in 2006.

23. Presidential Research Award from the President of Sri Lanka in 2005.

24. Presidential Research Award from the President of Sri Lanka in 2004.

25. Two Commendable research papers at the Annual Scientific Sessions, University of Peradeniya- 2003.

26. Presidential Research Award from the President of Sri Lanka in 2003.

27. Presidential Research Award from the President of Sri Lanka in 2001.

28. Best research paper – Annual Research Sessions of Faculty of Dental Sciences, University of Peradeniya, Sri Lanka in 2000.

29. Oration of the Sri Lanka Dental Association for the year 2000. Impact of new diagnostic techniques on clinicians and patients.

Guest Lectures (National and International)

1. Lecture titled “Oral potentially malignant disorders and WHO Classification

of Head and Neck tumours 2017” Kathmandu, Nepal, December 2017.

2. Lecture titled “WHO classification on Head and Neack tumours 2017; Major changes. 3rd Asian Maxillofacial Trainees conference, Colombo, Sri Lanka, November 2017.

3. Lecture titled “Grading of epithelial dysplasia” WHO 2017 for College of Pathologists of Sri Lanka, SLMA, Colombo, October 2017.

4. Lecture titled “Changes to Classification of Salivary tumours; WHO 2017” for College of Pathologists of Sri Lanka, SLMA, Colombo, October 2017.

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5. Lecture titled “Changes to Classification of Odontogenic tumours; WHO 2017

for College of Pathologists of Sri Lanka, SLMA, Colombo, October 2017

6. Guest lecture titled “Diagnosis of rare lesions in the Oral and Maxillofacial region”. 8th ASOMP meeting, Vijayawada, India, August 2017.

7. Guest lecture titled “Scenario of Oral Pathology in Asia”. 8th ASOMP meeting, Vijayawada, India, August 2017.

8. Guest lecture titled “Scope of Dental profession in a global perspective” at the Faculty Open day for Diamond Jubilee celebrations of University of Peradeniya, June 2017.

9. Guest lecture titled Grading oral epithelial dysplasia in potentially malignant disorders; caveats and practical guidelines. 6th World Oral Cancer Congress of International Academy of Oral Oncology (IAOO), May 2017, India.

10. Guest lecture titled Dysplasia at Surgical Margin, 6th World Oral Cancer Congress of International Academy of Oral Oncology (IAOO), May 2017, India.

11. Guest lecture titled  Pathology of Oral Potentially Malignant Disorders 6th World Oral Cancer Congress of International Academy of Oral Oncology (IAOO), May 2017, India

12. Guest lecture titled Concepts of Aetiopathogenesis and Malignant Transformation of Oral Submucous Fibrosis, 6th World Oral Cancer Congress by International Academy of Oral Oncology (IAOO), May 2017, India.

13. Guest lecture titled Global career pathways in Dentistry at the 9th national dental students scientific conference, Penang, Malaysia, May, 2017.

14. Guest lecture titled “Towards a smokeless Tobacco free Sri lanka” Conference organised by National Authority on Tobacco and Alcohol, November 2016.

15. Guest lecture titled “An overview of CROC and use of current understanding of OSF for future. International Conference on oral cancer, smokeless tobacco and arecanut, 2016, Kandy, Sri lanka

16. Guest lecture titled “Role of Pathology in the management of oral cancer and OPMD”. The International Odonto-Stomatology Conference on Science and Education, Hanoi, Vietnam, Oct 2016.

17. Guest lecture titled “Role of Pathology in the management of oral cancer and OPMD”. Inaugural Annual Scentific Sessions, Polonanaruwa Clinical Society Sep 2016.

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18. Keynote speech titled “Tropical Diseases; update” World congress on Oral pathology and Medicine, International Association of Oral Pathologists, Chennai, India Sep 2016.

19. Guest lecture titled “Malignant Transformation of Oral Submucous fibrosis” World congress on Oral pathology and Medicine, International Association of Oral Pathologists, Chennai, India Sep 2016.

20. Keynote speaker on the topic “Collaborations; the pathway to success” at the 4th conference on Japan- Sri Lanka Collaborative Research organised by Sri Lanka Japan study centre. Aug 2016, Kandy, Sri Lanka.

21. Guest lecture titled “Grading Epithelial Dysplasia” at the 27th meeting of Japanese Society of Oral Pathology, Hiroshima, Japan. August 2016.

22. Guest lecture titled “An overview of CROC and use of current understanding of OSF for future interventions” July 2016, University of Peradeniya, Sri Lanka.

23. Panel member on Cancer at the NSF Research Summit 2016.

24. Guest Lecture titled “Aetiology and pathogenesis of Oral submucous fibrosis” at the International Symposium on OSF, Nagpur India, Feb 2016.

25. Invited speaker for the panel discussion on Oral Submucous Fibrosis at the International Symposium on OSF, Nagpur India, Feb 2016.

26. Invited speaker for the panel on “Global Oral Cancer Status; regional disparities” at the 1st Global Oral Cancer Forum, New York, USA March 2016.

27. Invited Lecture at the “World Oral Health Day” and the Chief Guest of the national ceremony 2016.

28. Guest Lecture titled “How to get my paper published” Research Symposium, Faculty of Engineering, University of Peradeniya

29. Guest Lecture titled “How to expand an abstract to a full paper” conducted by Research and Development unit of Faculty of Medicine, University of Peradeniya, Sri Lanka, March 2016.

30. Guest lecture titled “Role of cytopathology in the diagnosis of salivary gland tumours” Oral Disease update meeting, University of Malaya, Kuala Lumpur, Malaysia, August 2015.

31. Guest lecture titled “The importance of clinicopathological correlation in the diagnosis of fibro osseous lesions” Oral Disease update meeting, University of Malaya, Kuala Lumpur, Malaysia, August 2015.

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32. Guest Lecture titled “Why Sri Lanka should panic about smokeless tobacco” at the National summit on Towards Tobacco and Alcohol Free Sri Lanka, Colombo, Sri Lanka, Feb 2015.

33. Guest Lecture titled “How to get my paper published” Kandy Society of Medicine, Oct, 2014.

34. Guest lecture titled “Why research? Sri Lankan perspectives”. Annual Scientific Sessions, College of Dentistry and Stomatology of Sri Lanka, Aug, 2014, Colombo.

35. Guest lecture titled “Current concepts of pathogenesis and malignant transformation of Oral Submucous fibrosis. Master Class series by International Association of General Dentistry, Bangalore, India, March 2014.

36. Guest lecture titled “Rare lesions of the oral and maxillofacial region”. Master Class series by International Association of General Dentistry, Bangalore, India, March 2014.

37. Guest lecture titled “Professional Ethics for Postgraduate trainees in different Dental specialities in the country organised by Ministry of Health. March 2014, Peradeniya.

38. Guest lecture titled “Mechanisms of aetilogy and pathogenesis of Oral Submucous fibrosis” Asian Sopciety of Oral Pathology, Hyderabad, India February 2014.

39. Guest lecture titled “Current criteria/concept for grading dysplasia” at the first Asian Consortium on Verrucopapillary lesions, University of Malaya, Malaysia, December 2013

40. Delivered keynote address as the Guest of Honour at the Galoya Nimna annual Scientific Sessions: November 2013

41. Guest lecture titled “How to get my paper published” Kandy Society of Medicine, October 2013.

42. Guest lecture titled “How to get my paper published” College of Radiologists of Sri Lanka, 2013.

43. Guest lecture titled “Pathological aspects of management of oral cancer” Annual Scientific Sessions of Oral and Maxillofacial Surgeons of Sri Lanka, 2013.

44. Guest lecture titled “Novel markers in the understanding of Oral Cancer and Precancer” at University Teknology MARA, Malaysia. Professorial Lecture series 2013.

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45. Guest lecture at the FDI/CDA/SLDA International Dental Congress, Lecture titled Pathological aspects of Management of Oral Potentially Malignant Disorders. July, 2013.

46. Guest lecture titled “Mechanisms of pathogenesis and malignant transformation of oral potentially malignant disorders” University of Otago, New Zealand, 2013.

47. Guest lecture titled “Prognostic markers of oral squamous cell carcinoma” University of Otago, New Zealand, 2013.

48. Guest lecture titled “Oral submucous fibrosis; Pathogenesis and malignant transformation” at the International conference on Diabetes and Cancer (Dia Can 2012) at Annamalai University, India, December 2012.

49. Guest lecture on” Future of Oral Pathology in the global context” at the 16th Congress of International association of Oral Pathologists, Sao Paulo, Brazil August, 2012.

50. Keynote address on the topic “Recent advances in oral potentially malignant disorders; Sri Lankan experience” at the 25th annual scientific sessions of the College of Dentistry and Stomatology of Sri Lanka. March, 2012 Colombo

51. Guest lecture on “concepts and natural history of oral potentially malignant disorders” at the Post Congress Oral cancer symposium of International Congress of the Asia Pacific Academic Consortium for Public Health, Sri Lanka, October, 2012.

52. Guest lecture on “Oral potentially malignant disorders in general dental practice” SLDA Regional Scientific Sessions 2012, Galle, Sri Lanka.

53. Guest lecture titled “Update on Oral cancer and Precancer” for Dental Surgeons organised by Dental Institute Maharagama. 2012

54. Guest lecture titled “Role of Oral Pathology in the management of Oral cancer. Sri Lanka Association of Maxillofacial Surgeons, Matale, Sri Lanka 2011.

55. Guest lecture titled “Natural history of Oral potentially malignant disorders in South Asia. National conference of Indian Association of Oral Pathologists, 2011, Hyderabad, India.

56. Guest lecture titled “The current situation of Oral Pathology in Sri Lanka” at the School of Dentistry, Achi Gakuin University, Nagoya, Japan, Aug 2011.

57. Guest lecture at the Symposium on Education of Oral Pathology in Asia; towards standardization and accreditation of Oral Pathologists in Asia, Asian Society of Oral Pathologists meeting in Fukuoka, Japan, Aug 2011.

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58. Guest lecture titled “Pathology of Oral Cancer and Precancer. Penang International Dental College, Malaysia, March 2011.

59. Guest speaker at the Asia Pacific Dental Congress in May 2010 in Colombo, Sri Lanka on “Importance of Pathology in the management of Oral cancer and Precancer.

60. Chairman and a Guest speaker in a symposium on Oral submucous fibrosis at the 15th meeting of the International Association of Oral Pathologists (IAOP) 16th -20th August 2010 in Seoul Korea.

61. Guest lecture on Salivary gland diseases organised by Badulla Clinical Society, 2010.

62. Guest lecture on “Pathogenesis of Oral Submucous fibrosis” at the Interantional conference of Indian Association of Oral Pathologists, 2010, Chennai India.

63. Guest lectures on “Views on better care for OPMD and Oral cancer in Sri Lankan context” Annual Scientific sessions of College of Stomatology and Dentistry in Sri Lanka Feb 2009

64. Panellist of the symposium on Tobacco and Oral diseases at the 14th world congress on tobacco or health in Mumbai India March 2009.

65. Guest lecture titled “Oral potentially malignant disorders; an update” Annual Scientific sessions of Sri Lanka Dental association Kandy Branch, 2009.

66. Guest lecture on Oral Submucous Fibrosis at the London Oral Biology group in London, UK, 2007

67. Guest lecture on “Update on Odontogenic tumours” at the Annual Scientific Sessions 2007, Sri Lanka Association of Oral & Maxillofacial Surgeons, Kandy, Sri Lanka

68. Guest lecture on “Current status of oral cancer in Sri Lanka”. International Oral cancer and cancer prevention conference, Seoul, South Korea-November 2006.

69. Update on blistering disorders of the Oral mucosa. Annual Scientific Sessions of Sri Lanka Dental Association June 2003.

70. Treatment of Oral Cancer in Sri Lanka “Pathologist’s view” Indo- Lanka

conference of Oral and Maxillo-facial Surgeons, Colombo, June 2003. 71. Viral infections of the oral mucosa. CME lecture, Sri Lanka Dental

Association Nov 2003.

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72. Guest lecture on “Pattern of recurrence of Ameloblastoma”. Asian Soceity of Oral Pathologists, Awajishima, Japan Aug 2003

73. Immunopathology of autoimmune bullous dermatoses. Guest lecture at the annual academic sessions & Joint Meeting with German Dermatological Society held from 14-17th February 2002. Colombo & Kandy.

74. Is the pattern of invasion a reliable predictor of progress of Oral Squamous

Cell Carcinoma? University of Niigata, Japan. February 2002

75. Classifications and Pathogenesis of Periodontal Disease. SLDA, Colombo. October 2002

76. Update on Precancer. SLDA, Regional sessions, Hambantota, Sri Lanka,

November 2002.

77. Rare Tumours/Pathology Update. Guest Lecture at the Annual Scientific Sessions 2002, Sri Lanka Association of Oral & Maxillofacial Surgeons.10th October 2002.

78. Pathology of Oral Cancer and Pre Cancer Dhaka Dental College, Bangladesh

May 2002

79. Challenges in diagnosing salivary gland tumours. Guest lecture at the annual Academic Sessions of the College of Pathologists of Sri Lanka, 17th and 18th August, 2001, Kandy.

80. Panel Discussion on the topic "Oral Cancer" International Dental Congress.

2001. Colombo, Sri Lanka.

81. Guest lecture titled; "Value of histological parameters of Oral Cancer in Predicting the Prognosis of Oral Cancer". Tokyo, Japan. January 2001.

82. Lecture on the topic "Pathology of oral mucosal lesions", 01st May 2000 for

Dental hygienists from Japan organized by the Dept. of Oral Medicine, Faculty of Dental Sciences, University of Peradeniya in collaboration with the project office JICA Dental education project, Peradeniya.

83. Conducted a Guest lecture on the topic: What is new in salivary gland tumour pathology? Kandy society of Medicine sessions. February 2000.

84. Guest lecture on the topic "What is new in salivary neoplasia?" on 03rd June

1999 organized by the Sri Lanka Dental Association (Kandy branch).

85. Recent advances in salivary neoplasia. Annual Scientific sessions of the College of Dentistry and Stomatology of Sri Lanka 1999.

86. Role of Immunofluorescence in the diagnosis of autoimmune dermatoses.

Joint Scientific Sessions of Sri Lanka Medical Association and Ruhuna Clinical Society - 1999.

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87. Guest lecture on “underlying pathology on the denture base area” College of

Dentistry and stomatology of Sri Lanka 1996.

International conferences/seminars

1. WHO meeting of SEAR on Smokeless tobacco policy, Delhi, India, August 2017.

2. 8th ASOMP meeting, Vijayawada, India, August 2017 3. 6th World Oral Cancer Congress by International Academy of Oral

Oncology (IAOO), May 2017, India 4. 9th national dental students scientific conference, Penang, Malaysia, May,

2017. 5. The International Odonto-Stomatology Conference on Science and

Education, Hanoi, Vietnam, Oct 2016. 6. World congress on Oral pathology and Medicine, International

Association of Oral Pathologists, Chennai, India Sep 2016 7. 27th meeting of Japanese Society of Oral Pathology, Hiroshima, Japan.

August 2016 8. 1st Global Oral Cancer Forum, New York, USA March 2016 9. International Symposium on OSF, Nagpur India, Feb 2016 10. Oral Disease update meeting, University of Malaya, Kuala Lumpur,

Malaysia, August 2015. 11. Chairman of the symposium on Oral cancer in Asia; 6th Hiroshima

conference, Hiroshima Japan October, 2015. 12. International symposium on oral cancer and cancer prevention. Yonsei

University, Seoul Korea, October 2015 13. 17th International Congress on Oral pathology and Medicine, Istanbul,

Turkey, May 2014. 14. 6th Asian Society of Oral Pathology Conference, Hyderabad, India

February 2014 15. International Association of Oral Pathologist: 16th Congress, Brazil, 2012 16. Symposium on Standardization of Oral Pathology in Asia. 5th ASOMP

meeting in Japan Aug 2011. 17. Indian Association of Oral Pathology Conference, Hyderabad, India, 2011 18. Indian Association of Oral Pathology Conference, Chennai, India, 2010 19. World work shop on Oral Medicine, September 2010, London UK 20. International Association of Oral Pathologists meeting (IAOP) in Seoul

South Korea August 2010 21. British Society of Oral and maxillofacial Pathology meeting in London

May 2010 22. 14th World Conference on Tobacco or Health in Mumbai, India. March

2009 as a Guest Speaker 23. 2nd World Congress on Oral Cancer Toronto, Canada, 2009 24. Annual Research sessions of Niigata University School of Medical and

Dental Sciences 2009

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25. Asian Society of Oral Pathology meeting in Beijing, China. November 2009

26. IAOP – 14th International Congress on Oral Pathology and Medicine jointly held with the American Academy of Oral and Maxillofacial Pathology in San Francisco, USA June 2008.

27. First World Congress on Oral Cancer, Amsterdam, Netherlands Aug 2007 28. Joint meeting of British Society of Oral Pathology and Medicine, London,

UK, 2007 29. Guest Lecture on “Current status of oral cancer in Sri Lanka”.

International Oral cancer and cancer prevention conference, Seoul, South Korea-November 2006.

30. British Society of Oral Pathology, Cardiff, Wales, UK 2006 31. Seminar on “Good clinical practice”, Queen Mary University of London,

December 2005. 32. Cancer stem cell symposium, Institute of cell and molecular sciences,

QMUL, London, UK. 33. 16th Annual meeting of the Japanese Society of Oral Pathology (JSOP).

August, 2005, Morioka, Japan 34. Visiting Professor to Niigata University Medical and Dental School, Japan

from August to December 2004 35. Guest lecture on “Pattern of recurrence of Ameloblastoma”. Asian Soceity

of Oral Pathologists, Awajishima, Japan Aug 2003. 36. Research collaboration on Oral submucous fibrosis in Niigata, Japan

August 2003. 37. 12th World Congress on Tobacco or Health in Helsinki, Finland. March

2003 38. 11th Biennial meeting of the International Association of Oral Pathologists

in Singapore (Panelist in a symposium) August 2002 39. Third Country Training Programme and guest lecture on Oral Cancer

Control, Dhaka, Bangladesh. May 2002 40. Research Meeting and guest lecture on Oral Cancer in Niigata, Japan

January 2002. 41. International Dermatopathology conference in New Delhi, India.

November 2001 42. Guest lecture titled; "Value of histological parameters of Oral Cancer in

Predicting the Prognosis of Oral Cancer". Tokyo Medical and Dental University, Japan. January 2001.

43. Research Meeting in Hokkaido, Japan. January/February 2001. 44. International Association of Oral Pathologists meeting, Cape town, South

Africa, 1998 45. International Association for Dental Research meeting, Nice, France, 1997 46. International Association for Dental Research meeting Sussex UK, 1996

43

Referees Prof. PR Morgan

Department of Oral Medicine and Pathology Floor 28 GKT Dental Institute Guy’s Hospital London SE1 9RT Email : peter.r.morgan@kcl.ac.uk Prof T Saku Division of Oral Pathology Graduate School of Medical and Dental sciences University of Niigata Japan Email: tsaku@dent.niigata-u.ac.jp Prof LP Samaranayake Former Dean, Faculty of Dentistry, University of Hong Kong Email: lakshman@hkucc.hku.hk