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Abordagem de Massas Cervicais Pediátricas Dr. Leonardo Guimarães Rangel Cirurgião de Cabeça e Pescoço Staff do HUPE-UERJ Doutorando em Cirurgia

Massa cervical pediatrica

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Page 1: Massa cervical pediatrica

Abordagem de Massas Cervicais Pediátricas

Dr. Leonardo Guimarães Rangel Cirurgião de Cabeça e Pescoço

Staff do HUPE-UERJ Doutorando em Cirurgia

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Aula disponível no

www.slideshare.net/leonardorangel

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Abordagem Inicial

3 Perguntas

Quando ?

Aonde ?

De Onde ? ?

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Abordagem Inicial

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Abordagem Inicial

Quando

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Abordagem Inicial

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Abordagem Inicial

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Abordagem Inicial

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Abordagem Inicial

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Abordagem Inicial

Aonde

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Abordagem Inicial

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tipos de massas cervicais

Congênitas Inflamatórias

Neoplásicas

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tipos de massas cervicais

Congênitas Inflamatórias

Neoplásicas De Onde

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Quando De Onde

Aonde

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Quando De Onde

Aonde

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Quando De Onde

Aonde

DX

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Inflamatórias Linha Média ∆ anterior ∆ posterior

Adenites Adenites Adenites

1ª Viral 2ª Bacteriana

3ª granulomatosa

1ª Viral 2ª Bacteriana

3ª granulomatosa1ª Viral

2ª Bacteriana 3ª granulomatosaSialoadenites

Parotidea Submandibular

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Congênitas

Linha Média ∆ anterior ∆ posterior

Cisto Tireoglosso

Cisto Dermóide

Cistos Branquiais

Laringocele

Cisto Tímico

Linfangioma

Lipoma

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NeoplásicasLinha Média ∆ anterior ∆ posterior

Linfomas

Ca Tireóide

Linfomas

Linfangiomas

Lipomas

Metástases

Trato aerodigestivo

Face

Glomus

Tumor Corpo Carotídeo

Hemangiomas

Neurogênicos

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Anamnese

Infecções Respiratórias

Viagens Recentes

Contato com animais

Tratamentos dentários e saúde bucal

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Exame Físico

Carácterísticas da Lesão

Tamanho

Posição

Consistência

Aderência

Pulsátil

Ulcerada

Dor

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Avaliação Laboratorial

Hemograma Completo

Pesquisa de HIV 1 e 2

VDRL

VHS, PCR-t

LDH

Teste de Mantoux (PPD)

sorologia para CMV

sorologia para EBV

VDRL + FTA-abs

sorologia para Toxoplasmose

sorologia para Tularemia

sorologia para Histoplasmose

sorologia para Bartonela Henselae (arranhadura do Gato)

Dç Lyme ( IGM Borrelia)

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Exames de Imagem

Ultrassom

Custo x Benefício

Sólido x Líquido

Pús

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Exames de ImagemTC

Radiação Ionizante Contraste Iodado Sedação Mais Rápido

RNM

sem Radiação Sedação Mais Demorado

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Cisto Branquial

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Cisto Branquial

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Cisto Branquial

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Cisto Branquial

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Cisto Branquial

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Cisto tireoglosso

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Cisto tireoglosso

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Cisto tireoglosso

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Linfangioma

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Linfangioma

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Linfangioma

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Linfangioma

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Linfangioma

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Linfangioma

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Linfangioma

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Glândulas Salivares Tumores

São Raros

Parótida (+ comum)

65% benignos

hemangioma

linfangioma

35% malignos

ca mucoepidermóide

Page 41: Massa cervical pediatrica

Glândulas Salivares Tumores

São Raros

Parótida (+ comum)

65% benignos

hemangioma

linfangioma

35% malignos

ca mucoepidermóide

Page 42: Massa cervical pediatrica

Glândulas Salivares Tumores

São Raros

Parótida (+ comum)

65% benignos

hemangioma

linfangioma

35% malignos

ca mucoepidermóide

Page 43: Massa cervical pediatrica

Glândulas Salivares Tumores

São Raros

Parótida (+ comum)

65% benignos

hemangioma

linfangioma

35% malignos

ca mucoepidermóide

Page 44: Massa cervical pediatrica

Glândulas Salivares Tumores

São Raros

Parótida (+ comum)

65% benignos

hemangioma

linfangioma

35% malignos

ca mucoepidermóide

Page 45: Massa cervical pediatrica

Glândulas Salivares Tumores

São Raros

Parótida (+ comum)

65% benignos

hemangioma

linfangioma

35% malignos

ca mucoepidermóide

Page 46: Massa cervical pediatrica

Glândulas Salivares Tumores

São Raros

Parótida (+ comum)

65% benignos

hemangioma

linfangioma

35% malignos

ca mucoepidermóide

Page 47: Massa cervical pediatrica

Glândulas Salivares Tumores

São Raros

Parótida (+ comum)

65% benignos

hemangioma

linfangioma

35% malignos

ca mucoepidermóide

Page 48: Massa cervical pediatrica

Processo inflamatório recorrente das glândulas salivares.

Aumento de volume

Dor

Febre

Mal estar

Saliva mucopurulenta

Fluxo salivar Diminuido

Glândulas Salivares Parotidite Recorente da Infância

Page 49: Massa cervical pediatrica

Processo inflamatório recorrente das glândulas salivares.

Aumento de volume

Dor

Febre

Mal estar

Saliva mucopurulenta

Fluxo salivar Diminuido

Glândulas Salivares Parotidite Recorente da Infância

Unilateral

Page 50: Massa cervical pediatrica

Glândulas Salivares Parotidite Recorente da Infância

Entidade Rara

Início: 8 meses – 16 anos

♂ > ♀

Episódios ao ano : 2-10

Evolução : remissão após adolescência

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Hemangiomas

Capilares

Mistos

Cavernoso

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Hemangiomas

Capilares

Mistos

Cavernoso

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Hemangiomas

Capilares

Mistos

Cavernoso

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Hemangiomas

Capilares

Mistos

Cavernoso

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Hemangiomas

Capilares

Mistos

Cavernoso

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Linfonodos !

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http://histology.medicine.umich.edu/resources/lymphatic-system

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Junqueira, 12ªed

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Anatomia Ultrassonográfica

Anatomy 59

Fig. 6.1 Histology of a typical cervical lymph node. The trabeculae extending centrally from the periphery represent the lymph node hilum and contain, among other things, the blood vessels (asterisk). (Reproduced with kind permission of A. Agaimy MD, Institute of Pathology, Erlangen University Hospital, Germany.)

Fig. 6.2a Right side of the neck, transverse, level II. An oval lymph node in acute lymphadenitis colli (RF); the node has a delicate internal echo pattern with well-defined margins and measures 30 mm × 15 mm in both short-axis diameters. A clearly visible incidental finding is the nerve bundle of the vagus nerve seen in cross-section between the internal (ACI) and external (ACE) carotid arteries (asterisk). GSM, submandibular gland.

Homogeneity of the intranodal EchotextureAccording to classical teaching, the lymph node cortex (hypoechoic) and hilum (echogenic) show a homogeneous structure on ultrasound (Fig. 6.18). The presence of a markedly inhomogeneous echotexture is a relevant criterion of malignancy (Figs. 6.19, 6.20, 6.21).

Pearls and PitfallsIt is becoming problematic that the latest ultrasound scanners with higher resolution and improved displays hardly ever show completely homogeneous lymph nodes; rather they nearly always demonstrate some inhomogeneous—but not actually malignant—textural elements.

If the lymph node structure is altered as the result of a malignant trans-formation, the distinction between cortex and hilum is lost (Fig. 6.22). The echotexture is inhomogeneous with anechoic areas indicating necrosis and reduced perfusion of the center of the tumor (Figs. 6.23, 6.24).

On the other hand, a central anechoic area in a reactive cervical lymph node is typical of abscess formation. Liquefaction with a cen-tral anechoic area is seen particularly in mycobacteria infections and actinomycosis (see below). In contrast, echogenic reflections or calci-fication are characteristically seen in tuberculosis and in the case of metastases of papillary carcinoma of the thyroid.

Lymph Node Distribution

Level in the NeckIf there is an inflammatory process, the lymph nodes in the drainage channels of the affected organs show reactive changes. Hugely enlarged cervical lymph nodes in the lower neck are relatively less often affected by inflammation and are therefore detectable more often in the pres-ence of malignancy. The overall clinical situation must also be taken into account to be able to make an appropriate assessment (Fig. 6.25).

Noting the distribution of lymphadenopathy helps in narrowing down the differential diagnosis (Figs. 6.26, 6.27). Lymph node metas-tases from solid tumors are usually found initially in groups sited in the relevant lymphatic drainage channels. Particularly in cervical cases, the manifestation of many types of malignant lymphoma tends to appear in a conglomerate pattern.

*

*

Pearls and PitfallsThe ultrasound criteria for assessing whether or not a cervical lymph node is malignant are:

1. Size and three-dimensional proportions2. Detectability of a lymph node hilus, perfusion pattern3. Lymph node shape4. Border of the lymph node5. Homogeneity of the intranodal structure6. Distribution of the lymph nodes

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Características Ultrassonográficas

Tamanho

referência : menor eixo

Níveis IB e II =8mm , IA, III, IV e V = 5mm

limite da detecção de metástases 3mm - para qualquer método

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Características Ultrassonográficas

Formato

Solbati Index : maior/menor eixo

normal (1,5-2,0)

LFN inflamados aumentam mas mantém a forma

linfonodos metastáticos são redondos

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Características Ultrassonográficas

Sinal Do Hilo

Benignidade

60 6 Neck Lymph Nodes

II So

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c An

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d Pa

thol

ogy

Fig. 6.4 Left side of the neck, transverse, CCDS. A round, clearly defined lymph node lateral to the common carotid artery (ACC), with a classical “hilar sign” and hilar perfusion seen on CCDS. The afferent and efferent hilar vessels can also be identified at the right border of the node. In this case, the massive enlargement of the node with maintenance of the normal vascular and hilar structures was due to non-Hodgkin lymphoma. A cystic mass in the lower neck area may also be found with metastases of papillary thyroid carcinomas.

Fig. 6.2b Right side of the neck, longitudinal, level II. The oval lymph node seen in acute lymphadenitis colli measures 32 mm on its long axis.

Fig. 6.3 Left side of the neck, transverse, level V. This lymph node shows a characteristic pattern of inflammation (kidney shape, hilar sign, homo-geneous texture). MSCM, stemocleidomastoid muscle, VJI, internal jugular vein, WS, vertebral spine.

60 6 Neck Lymph Nodes

II So

nogr

aphi

c An

atom

y an

d Pa

thol

ogy

Fig. 6.4 Left side of the neck, transverse, CCDS. A round, clearly defined lymph node lateral to the common carotid artery (ACC), with a classical “hilar sign” and hilar perfusion seen on CCDS. The afferent and efferent hilar vessels can also be identified at the right border of the node. In this case, the massive enlargement of the node with maintenance of the normal vascular and hilar structures was due to non-Hodgkin lymphoma. A cystic mass in the lower neck area may also be found with metastases of papillary thyroid carcinomas.

Fig. 6.2b Right side of the neck, longitudinal, level II. The oval lymph node seen in acute lymphadenitis colli measures 32 mm on its long axis.

Fig. 6.3 Left side of the neck, transverse, level V. This lymph node shows a characteristic pattern of inflammation (kidney shape, hilar sign, homo-geneous texture). MSCM, stemocleidomastoid muscle, VJI, internal jugular vein, WS, vertebral spine.

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Características Ultrassonográficas

Bordas

Bem demarcadas

Movimento livre

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Características Ultrassonográficas

Homogeniedade

Hilo hiperecóico

cortex Hipoecóico

Anatomy 67

Fig. 6.23 Left side of the neck, longitudinal, level III. A round lymph node metastasis with irregular borders has an anechoic center, which is indicative of necrosis caused by the metastatic transformation. VJI, internal jugular vein; MSCM, sternocleidomastoid muscle.

Fig. 6.24 Left side of the neck, level II. Medial to the internal and external carotid arteries, the round metastasis has an anechoic center consistent with central necrosis; this is considered to be a sign of malignancy. To the left, medial in the image, is an ill-defined hypoechoic primary tumor (TU) of the left side of the oropharynx. The internal jugular vein (VJI) is compromised and can be seen between the anterior border of the sternocleidomastoid muscle (MSCM) and the internal carotid artery (ACI). The vein can be demonstrated better with a Valsalva maneuver. ACE, external carotid artery.

Fig. 6.25 Split screen, right side of the floor of the mouth. The two round paramedian lymph nodes with inhomogeneous internal echoes lie on the right in level IA. If there were an acute dental infection, these two lymph nodes (RF1 and RF2), both showing a weak “hilar sign” and clearly defined margins, would be consistent with reactive enlargement; however, both lymph nodes can definitely be considered possible metastases when there is clinical suspicion of cancer of the floor of the mouth, tongue, or sinonasal area. MD, digastric muscle; MGH, geniohyoid muscle; MM, mylohyoid muscle. Histological diagnosis: Lymph node metastasis.

Page 65: Massa cervical pediatrica

Características Ultrassonográficas

Homogeniedade

Hilo hiperecóico

cortex Hipoecóico

Anatomy 67

Fig. 6.23 Left side of the neck, longitudinal, level III. A round lymph node metastasis with irregular borders has an anechoic center, which is indicative of necrosis caused by the metastatic transformation. VJI, internal jugular vein; MSCM, sternocleidomastoid muscle.

Fig. 6.24 Left side of the neck, level II. Medial to the internal and external carotid arteries, the round metastasis has an anechoic center consistent with central necrosis; this is considered to be a sign of malignancy. To the left, medial in the image, is an ill-defined hypoechoic primary tumor (TU) of the left side of the oropharynx. The internal jugular vein (VJI) is compromised and can be seen between the anterior border of the sternocleidomastoid muscle (MSCM) and the internal carotid artery (ACI). The vein can be demonstrated better with a Valsalva maneuver. ACE, external carotid artery.

Fig. 6.25 Split screen, right side of the floor of the mouth. The two round paramedian lymph nodes with inhomogeneous internal echoes lie on the right in level IA. If there were an acute dental infection, these two lymph nodes (RF1 and RF2), both showing a weak “hilar sign” and clearly defined margins, would be consistent with reactive enlargement; however, both lymph nodes can definitely be considered possible metastases when there is clinical suspicion of cancer of the floor of the mouth, tongue, or sinonasal area. MD, digastric muscle; MGH, geniohyoid muscle; MM, mylohyoid muscle. Histological diagnosis: Lymph node metastasis.

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Características Ultrassonográficas

Distribuição

número

distruição de acordo com a queixas

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Características Ultrassonográficas

Distribuição

número

distruição de acordo com a queixas

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Características Ultrassonográficas

Distribuição

número

distruição de acordo com a queixas

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Características Ultrassonográficas

66 6 Neck Lymph Nodes

II So

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Fig. 6.21 Split screen, right side of the neck, level III. A lymph node (RF) in a patient being followed up for malignant disease; the caudal margins show marked extension. Compared with the normal architecture, there is marked inhomogeneity. ACC, common carotid artery; VJI, internal jugular vein; MSCM, sternocleidomastoid muscle. Diagnosis: Lymph node metastasis recurrence, 6 months after initial multimodal treatment.

Fig. 6.22 A schematic representation of morphological changes in metastases. These morphological transfornations within a lymph node illustrate sonographic findings of malignancy.

Fig. 6.20 Split screen, right side of the neck, level IV, CCDS. The space-occupying lesion (RF) with an inhomogeneous echo pattern is sited laterally to the common carotid artery (ACC) and the internal jugular vein (VJI). The perfusion is peripheral and decentralized: in addition, irregular echogenic internal echoes are consistent with metastasis. MSCM, sternocleidomastoid muscle. Diagnosis: Lymph node metastasis.

Lymph nodeand its capsule

Fatty hilum composed offatty tissues surroundingthe hilum and medullaof a lymph node

Metastatic focus

Necrotic area withinthe metastatic focus

No changes in the size or formof the lymph node are evident.

Thickness is first affected(6 mm or greater in thickness).

The capsule also becomes thicker.

Although the entire lymphnode becomes enlarged,the capsule is retained.

A metastatic focus occupiesalmost the entire lymph node.

A border is clearly observed(10–20 mm in thickness;

can be identified even by CT).

The metastatic focusextends beyond the capsule

of the lymph node intosurrounding tissues. The border

becomes poorly demarcated.

1 2 3

7 6 5

4

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Características Ultrassonográficas

Lembrar

Tamanho e proporções

Hilo

formato

Borda

Homogeniedade

Distribuição

Page 71: Massa cervical pediatrica

Conclusão

Diversas etiologias

Avaliar melhor momento para abordagem

Evitar procedimentos desnecessários