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Os bastidores da Medicina Nuclear – Desafios e Esperanças
1950´s
• Construção do Reator IEA-R1
19561957
1959
19561957
• Criticalidade do Reator IEA-R1
• 131Iodo por técnica de destilação úmida
19561957
1959
Primeira dose de 131 Iodo para a ClínicaVillela Pedras (Clínica de Radioterapia
Medicina Nuclear Costa Júnior – Rio de Janeiro
1960´s
1960´s
32P198Au42K24Na51Cr
1970´s
19741979
Construção do Prédio onde atualmente estão localizados o Controle de Qualidade e Produção de kits de reagentes liofilizados
19741979
BRA6005 Nuclear Medicine 1976
Moléculas marcadas com 131 I Produção de Kits para marcação com 99mTc
1980´s
1980
19811985
1980
1981 1989
99Mo/99mTc Gerador131I MIBGMoléculas marcadas com51Cr 123I 67Ga
BRA6006 - Radiopharmaceuticals 1980RLA - Quality Control of Nuclear Medicine Procedures in Vivo 1980BRA 6008 - Radioisotopes in Clinical Medicine 1981BRA6009 - Radioisotopes in Medicine 1982BRA6010 - Radioisotopes in Medicine 1983RLA - TC on production and control ofradiopharmaceuticals 1983BRA4039 - Production of Molybdenum-99 1989
1990´s
19931995
19971999
201Tl153S-EDTMP18F-FDG131I cápsula
BRA4040 - Radioisotope Production with a Cyclotron 1991RLA - Quality Assurance in Nuclear Medicine 1993RLA - TC on Radiopharmacy 1993BRA6013 - Traceability of Radionuclide Measurements and QA in Medicine 1999
2000´s
2005
20062007
2009
• CRP - Optimization of synthesis and quality control procedures for the preparation of fluorine-18 and iodine -123 labelled peptides2000
• RLA - Preparación, controle de calidad y validación de radiofármacos de 99mTc, basados em anticuerpos monoclorares2004
• CRP - Development of Generator Technologies for Therapeutic Radionuclides (188W-188Re e 90Sr-90Y)” 2004
• CRP - Development of therapeutic radiopharmaceuticals based on 177Lu for radionuclide therapy 2005
• RLA - Strengthening Quality Assurance in Nuclear Medicine 2009
111In-Octreotideo177Lu Dotatato18F-NaF131Iodo técnica de destilação seca
19 Latin Americans training funded by the AIEA
2010´s
68Ga -DOTATATE
18F -Choline
18F FLT
177Lu -PSMA
•CRP – Development of Therapeutic Radiopharmaceuticals Based on 188Re and 90Y for Radionuclide Therapy – 2008
•CRP - Developing Techniques for Small-Scale Indigenous Mo-99 Production using LEU Fission or Neutron Activation 2009
•CRP – Preclinical Evaluation and Formulation of 177Lu and 90Y –Labelled and Monoclonal Antibodies for Cancer Therapy 2010
•CRP - Development of 68Ga based PET radiopharmaceuticals for management of cancer and other chronic diseases - 2013
•RLA - Curso Regional de Capacitación sobre Validación 2016
•BRA - Improving protocols in nuclear medicine services and in the development of new radiopharmaceuticals 2016
•CRP - Copper-64 Radiopharmaceuticals for TheranosticApplication 2017
2012
2017
2019
1999
2005
2006
2007
2009
2012
2017
19931995
1997
19561957
1959
1960´s
19741979
1980
1981
1989
2019
32 radiofármacospara aproximadamente 2.000.000
procedimentos/ano
CINTILOGRAFIA COM IODO-131
continua.....
