Novos Critérios Les

8/18/2019 Novos Critérios Les

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Arthritis Rheum. Author manuscript; available in PMC Aug 1, 21!.

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Arthritis Rheum. Aug 212; #$%&': 2#(()2#.

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Table 3

Clinical an" /mmunologic Criteria 0se" in the /CC Classification Criteria.

Clinical Criteria

1. Acute cutaneous lupus

inclu"ing lupus malar rash %"o not count if malar "iscoi"'

bullous lupus

toxic epi"ermal necrol+sis variant of

maculopapular lupus rash

photosensitive lupus rash

in the absence of dermatomyositis

or subacute cutaneous lupus

%nonin"urate" psoriaform an"*or annular pol+c+clic lesions that resolve 3ithout scarring, although occasionall+ 3ithpostinflammator+ "+spigmentation or telangiectasias'

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409311/http://dx.doi.org/10.1002%2Fart.34473http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409311/table/T3/http://www.ncbi.nlm.nih.gov/pmc/about/copyright.htmlhttp://dx.doi.org/10.1002%2Fart.34473http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409311/table/T3/http://www.ncbi.nlm.nih.gov/pmc/about/copyright.htmlhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409311/


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Clinical Criteria

2. Chronic cutaneous lupus

inclu"ing classical "iscoi" rash

locali4e" %above the nec5'

generali4e" %above an" belo3 the nec5'

h+pertrophic %verrucous' lupus

lupus panniculitis %profun"us'

mucosal lupus

lupus er+thematosus tumi"us

chillblains lupus

"iscoi" lupus*lichen planus overlap

!. 6ral ulcers: palate

buccal

tongue

or nasal ulcers


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Clinical Criteria

in the absence of other causes, such as vasculitis, Behcets, infection (herpes), inflammatory bowel disease, reactivearthritis, and acidic foods

$. 7onscarring alopecia %"iffuse thinning or hair fragilit+ 3ith visible bro5en hairs'

in the absence of other causes such as alopecia areata, drugs, iron deficiency and androgenic alopecia

8. +novitis involving t3o or more 9oints, characteri4e" b+ s3elling or effusion 6R ten"erness in 2 or more 9oints an" thirt+minutes or more of morning stiffness.

#. erositis

t+pical pleuris+ for more than 1 "a+

or pleural effusions

or pleural rub

t+pical pericar"ial pain %pain 3ith recumbenc+ improve" b+ sitting for3ar"' for more than 1 "a+

or pericar"ial effusion

or pericar"ial rub

or pericar"itis b+


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Clinical Criteria

in the absence of other causes, such as infection, uremia, and Dressler's pericarditis

(. Renal

0rine protein*creatinine %or 2$ hr urine protein' representing 8 mg of protein*2$ hr

or

Re" bloo" cell casts

&. 7eurologic

sei4ures

ps+chosis

mononeuritis multiplex

in the absence of other known causes such as primary vasculitis

m+elitis

peripheral or cranial neuropath+

in the absence of other known causes such as primary vasculitis, infection, and diabetes mellitus

acute confusional state


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Clinical Criteria

in the absence of other causes, including toxic-metabolic, uremia, drugs

$*mm! at least once'

in the absence of other known causes such as elty's, drugs, and portal hypertension

6R

+mphopenia %> 1*mm! at least once'

in the absence of other known causes such as corticosteroids, drugs and infection

11. ?hromboc+topenia %>1,*mm!' at least once

in the absence of other known causes such as drugs, portal hypertension, and !!"

Immunological Criteria

1. A7A above laborator+ reference range

2. Anti@"s7A above laborator+ reference range, except /A: t3ice above laborator+

reference range


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Immunological Criteria

!. Anti@m

$. Antiphospholipi" antibo"+: an+ of the follo3ing

lupus anticoagulant

false@positive RPR

me"ium or high titer anticar"iolipin %/gA, /g or /gM'

anti@B2 gl+coprotein / %/gA, /g or /gM'

8. o3 complement

lo3 C!

lo3 C$

lo3 C=8

#. irect Coombs test in the absence of hemolytic anemia

Criteria are cumulative an" nee" not be present concurrentl+.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409311/table/T3/
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409311/table/T3/http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409311/table/T3/

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