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 Arthritis Rheum. Author manuscript; available in PMC Aug 1, 21!.

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Table 3

Clinical an" /mmunologic Criteria 0se" in the /CC Classification Criteria.

Clinical Criteria

1. Acute cutaneous lupus

  inclu"ing lupus malar rash %"o not count if malar "iscoi"'

  bullous lupus

  toxic epi"ermal necrol+sis variant of

  maculopapular lupus rash

  photosensitive lupus rash

  in the absence of dermatomyositis 

or subacute cutaneous lupus

  %nonin"urate" psoriaform an"*or annular pol+c+clic lesions that resolve 3ithout scarring, although occasionall+ 3ithpostinflammator+ "+spigmentation or telangiectasias'

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409311/http://dx.doi.org/10.1002%2Fart.34473http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409311/table/T3/http://www.ncbi.nlm.nih.gov/pmc/about/copyright.htmlhttp://dx.doi.org/10.1002%2Fart.34473http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409311/table/T3/http://www.ncbi.nlm.nih.gov/pmc/about/copyright.htmlhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409311/

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Clinical Criteria

2. Chronic cutaneous lupus

inclu"ing classical "iscoi" rash

  locali4e" %above the nec5'

  generali4e" %above an" belo3 the nec5'

  h+pertrophic %verrucous' lupus

  lupus panniculitis %profun"us'

  mucosal lupus

  lupus er+thematosus tumi"us

  chillblains lupus

  "iscoi" lupus*lichen planus overlap

!. 6ral ulcers: palate

  buccal

  tongue

  or nasal ulcers

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Clinical Criteria

  in the absence of other causes, such as vasculitis, Behcets, infection (herpes), inflammatory bowel disease, reactivearthritis, and acidic foods 

$. 7onscarring alopecia %"iffuse thinning or hair fragilit+ 3ith visible bro5en hairs'

  in the absence of other causes such as alopecia areata, drugs, iron deficiency and androgenic alopecia 

8. +novitis involving t3o or more 9oints, characteri4e" b+ s3elling or effusion 6R ten"erness in 2 or more 9oints an" thirt+minutes or more of morning stiffness.

#. erositis

  t+pical pleuris+ for more than 1 "a+

  or pleural effusions

  or pleural rub

  t+pical pericar"ial pain %pain 3ith recumbenc+ improve" b+ sitting for3ar"' for more than 1 "a+

  or pericar"ial effusion

  or pericar"ial rub

  or pericar"itis b+

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Clinical Criteria

  in the absence of other causes, such as infection, uremia, and Dressler's pericarditis 

(. Renal

  0rine protein*creatinine %or 2$ hr urine protein' representing 8 mg of protein*2$ hr 

  or 

  Re" bloo" cell casts

&. 7eurologic

  sei4ures

  ps+chosis

  mononeuritis multiplex

  in the absence of other known causes such as primary vasculitis 

m+elitis

  peripheral or cranial neuropath+

  in the absence of other known causes such as primary vasculitis, infection, and diabetes mellitus 

acute confusional state

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Clinical Criteria

  in the absence of other causes, including toxic-metabolic, uremia, drugs 

$*mm! at least once'

  in the absence of other known causes such as elty's, drugs, and portal hypertension 

6R

  +mphopenia %> 1*mm! at least once'

  in the absence of other known causes such as corticosteroids, drugs and infection 

11. ?hromboc+topenia %>1,*mm!' at least once

  in the absence of other known causes such as drugs, portal hypertension, and !!"  

Immunological Criteria

1. A7A above laborator+ reference range

2. Anti@"s7A above laborator+ reference range, except /A: t3ice above laborator+

  reference range

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Immunological Criteria

!. Anti@m

$. Antiphospholipi" antibo"+: an+ of the follo3ing

  lupus anticoagulant

  false@positive RPR

  me"ium or high titer anticar"iolipin %/gA, /g or /gM'

  anti@B2 gl+coprotein / %/gA, /g or /gM'

8. o3 complement

  lo3 C!

  lo3 C$

  lo3 C=8

#. irect Coombs test in the absence of hemolytic anemia

Criteria are cumulative an" nee" not be present concurrentl+.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409311/table/T3/

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409311/table/T3/http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409311/table/T3/