Tiago Bravo Ferreira, Tos Berendschot, Tiago Bravo ... · Hospital da Luz Methods Main outcome measures Monocular and binocular visual acuities –ETDRS charts under photopic conditions

Tiago Bravo Ferreira, Filomena RibeiroTiago Bravo Ferreira, Tos Berendschot,

Filomena Ribeiro

Tiago Bravo Ferreira, Tos Berendschot,

Filomena Ribeiro

Tiago Bravo Ferreira, Tos Berendschot,

Filomena Ribeiro

PROSPECTIVE COMPARATIVE STUDY OF BILATERALLY IMPLANTED

RAYONE TRIFOCAL VS FINEVISION POD F IN 60 EYES

Hospital da Luz – Lisbon, Portugal

Tiago B Ferreira

Tiago Ferreira’s Financial Disclosure 2018

My “Financial Interest” relevant to this presentation is highlighted in yellow bellow

J&J Vision – C, R

PhysIOL – R

Alcon – R

Ophtec – S

Tiago B Ferreira|ESCRS 2018 Hospital da Luz

RAYONE TRIFOCAL VS FINEVISION

Tiago B Ferreira|ESCRS 2018 Hospital da Luz

Purpose

To compare the clinical outcomes of two diffractive trifocal IOLs

✓ RayOne trifocal (Rayner)

✓ FineVision POD F (PhysIOL)


Hospital da Luz

Methods

✓ Prospective comparative randomized interventional study

✓ Patients submitted to cataract surgery (corneal astigmatism <0.75 D)

✓ 2 groups (1:1 randomization)

30 eyes (15 patients) – RayOne Trifocal

30 eyes (15 patients) – FineVision POD F

Mean Age 67.0 ± 6.9, Median age 68 (55-79)

✓ 3 months follow-up

Tiago B Ferreira|ESCRS 2018


Hospital da Luz

Methods

✓ Comprehensive preoperative ophthalmologic examination

✓ Optical biometry (Lenstar LS900; Haag-Streit AG)

Hill-RBF formula for IOL power calculation

Refractive target – first negative value

✓ Surgery – phacoemulsification with clear cornea temporal incision (2.2 mm)



Hospital da Luz

Methods

Main outcome measures

Monocular and binocular visual acuities – ETDRS charts under photopic conditions (85 candelas/m2)

✓ Uncorrected (UDVA) and corrected (CDVA) distance visual acuities

✓ Uncorrected (UIVA) and distance corrected (DCIVA) intermediate visual acuities at 70 cm

✓ Uncorrected (UNVA) and distance corrected (DCNVA) near visual acuities at 40 cm



Hospital da Luz

Main outcome measures

✓ Manifest refraction

✓ Defocus curves

✓ Contrast sensitivity

✓ Presence of photic phenomena



Methods

Hospital da Luz

Results



Post-Op Refractive results

36.7

46.7

16.7

± 0.50 D: 100%

± 1.00 D: 100%

16.7

53.3

20.0

10.0

± 0.50 D: 83.3%

± 1.00 D: 100%

0

10

20

30

40

50

< - 0

.51

-0.5

0 to

-0.1

4

-0.1

3 to

0.1

3

0.14

to 0

.50

> 0.

51

< - 0

.51

-0.5

0 to

-0.1

4

-0.1

3 to

0.1

3

0.14

to 0

.50

> 0.

51

Rayone Trifocal Finevision%

of e

yes

Diopter(D)

Spherical Equivalent Refraction Accuracy

% o

f e

ye

s

-.02

0

.02

.04

.06

.08

.1

.12

.14

UIV

A M

ono

cula

r

Rayone Trifocal Finevision

Mean and 95% Confidence Intervals

t-test: t=-1.2775, p=0.2067

UIVA Monocular

-.1

-.06

-.02

.02

.06

.1

DC

NV

A M

on

ocu

lar



t-test: t=-0.3558, p=0.7233

DCNVA Monocular

Hospital da Luz

Results



Monocular visual acuities

-.1

-.06

-.02

.02

.06

.1

UD

VA

Mo

no

cula

r



t-test: t=-0.5202, p=0.6049

UDVA Monocular

-.1

-.06

-.02

.02

.06

.1

CD

VA

Mo

no

cula

r



t-test: t=0.0164, p=0.9870

CDVA Monocular

0

.02

.04

.06

.08

.1

DC

IVA

Mon

ocu

lar



t-test: t=0.0124, p=0.9902

DCIVA Monocular

0

.02

.04

.06

.08

.1

UN

VA

Mo

no

cula

r



t-test: t=-0.1772, p=0.8599

UNVA Monocular

Hospital da Luz

Results



Monocular photopic (85.0 cd/m2) defocus curves

-.2

0

.2

.4

.6

Vis

ual A

cu

ity / log

MA

R

10.50-0.5-1-1.5-2-2.5-3-3.5-4DeFocus

Rayone Trifocal

Finevision

Defocus Curves

-.2

0

.2

.4

.6

Vis

ual A

cu

ity / log

MA

R

10.50-0.5-1-1.5-2-2.5-3-3.5-4

DeFocus

Rayone Trifocal

Finevision

Group effect F(1,318)=1.81, p=0.1793

Defocus Curves

Hospital da Luz

Results



0,00

20,00

40,00

60,00

1,5 3 6 12 18

Co

ntr

ast

Sen

siti

vity

Spatial Frequency (cycles per degree)

CSF (Photopic Conditions)

FineVision (n=30) RayOne Trifocal (n=30)

Photopic contrast sensitivity function (CSF) without glare – (Optec 6500, Stereo Optical, Inc.)

luminance level: 85.0 cd/m2

Hospital da Luz

Results



0,00

5,00

10,00

15,00

20,00

25,00

30,00

35,00

40,00

45,00

1,5 3 6 12 18

Co

ntr

ast

Sen

siti

vity

Spatial Frequency (cycles per degree)

CSF (Mesopic Conditions with Glare)


Mesopic CSF with glare – (Optec 6500, Stereo Optical, Inc.)

luminance level: 85.0 cd/m2

Hospital da Luz

Results



McAlinden QoV Questionnaire

0,00

5,00

10,00

15,00

20,00

25,00

30,00

35,00

40,00

Frequency Severity Bothersome

Qo

V S

core

[0

-10

0]

Score Category

RayOne Trifocal (n=30) FineVision (n=30)

Invest. Ophthalmol. Vis. Sci. 2010;51(11):5537-5545

Global Scores

Statistically significant difference between the 2 groups in Depth

Perception (p=0.042)

Photic phenomena – subjective evaluation

Hospital da LuzTiago B Ferreira|ESCRS 2018


Light-distortion analyzer

(HLMP-CW47-RU000, Agilent Technologies)

0,0

5,0

10,0

15,0

20,0

25,0

30,0

35,0

40,0

Ligh

t D

isto

rtio

n In

de

x (%

)

IOL Type


Results

Photic phenomena – objective evaluation

J. Biomed. Opt. 20(7) 075002 (6 July 2015)

Light distortion index (LDI)

percentage of the total tested area not visible

due to photic phenomena

Hospital da Luz

Conclusions



✓ Both IOLs offer excellent visual and refractive results

✓ Similar contrast sensitivity

✓ Less photic phenomena with the RayOne Trifocal

Hospital da Luz

Thank you


PROSPECTIVE COMPARATIVE STUDY OF BILATERALLY IMPLANTED

RAYONE TRIFOCAL VS FINEVISION POD F IN 60 EYES

Documents

Tiago Bravo Ferreira, Tos Berendschot, Tiago Bravo ... · Hospital da Luz Methods Main outcome measures Monocular and binocular visual acuities –ETDRS charts under photopic conditions